Gene Symbol | Synpo2 |
Entrez Gene ID | 118449 |
Full Name | synaptopodin 2 |
Synonyms | 1110069I04Rik,2310068J10Rik,9530006G20Rik,AI848603,Myo |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Synpo2 cDNA ORF clone
gRNAs
Gene Symbol | Synpo2 |
Entrez Gene ID | 118449 |
Full Name | synaptopodin 2 |
Synonyms | 1110069I04Rik,2310068J10Rik,9530006G20Rik,AI848603,Myo |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006500925.2 | XP_006500988.1 | synaptopodin-2 isoform X1 |
XM_006500925.3 | XP_006500988.1 | synaptopodin-2 isoform X2 |
NM_080451.2 | NP_536699.2 | synaptopodin-2 |
XM_030252390.1 | XP_030108250.1 | synaptopodin-2 isoform X1 |
Pan troglodytes (chimpanzee) | SYNPO2 | XP_001148597.1 |
SYNPO2 | XP_001098526.1 | |
Rattus norvegicus (Norway rat) | Synpo2 | NP_001178892.1 |
Canis lupus familiaris (dog) | SYNPO2 | XP_853728.2 |
Homo sapiens (human) | SYNPO2 | NP_597734.2 |
Bos taurus (cattle) | SYNPO2 | NP_001077220.1 |
Mus musculus (house mouse) | Synpo2 | NP_536699.2 |
Gallus gallus (chicken) | SYNPO2 | XP_426324.3 |
Xenopus tropicalis (tropical clawed frog) | synpo2 | XP_004911507.1 |
High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)
Regulation of smooth muscle dystrophin and synaptopodin 2 expression by actin polymerization and vascular injury.
Turczy?ska KM, Sw?rd K, Hien TT, Wohlfahrt J, Mattisson IY, Ekman M, Nilsson J, Sj?gren J, Murugesan V, Hultg?rdh-Nilsson A, Cidad P, Hellstrand P, P?rez-Garc?a MT, Albinsson S
Arteriosclerosis, thrombosis, and vascular biology35(6)1489-97(2015 Jun)
Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.
Thiagarajan RD, Georgas KM, Rumballe BA, Lesieur E, Chiu HS, Taylor D, Tang DT, Grimmond SM, Little MH
PloS one6(2)e17286(2011 Feb)
Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes.
Faul C, Dhume A, Schecter AD, Mundel P
Molecular and cellular biology27(23)8215-27(2007 Dec)
Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3.
Faul C, H?ttelmaier S, Oh J, Hachet V, Singer RH, Mundel P
The Journal of cell biology169(3)415-24(2005 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The identification of myopodin as a direct target of PKA, CaMKII, and calcineurin defines a novel intracellular signaling pathway whereby changes in Z-disc dynamics may translate into compartmentalized signal transduction in the heart.
Title: Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes.
The following Synpo2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Synpo2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu31576 | |
Clone ID Related Accession (Same CDS sequence) | XM_006500925.2 , XM_006500925.3 | |
Accession Version | XM_006500925.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3237bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | synaptopodin-2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006500925.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCACCG GAGATTTCAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006500988.1 |
CDS | 162..3398 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCACCG GAGATTTCAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu88146 | |
Clone ID Related Accession (Same CDS sequence) | XM_030252390.1 | |
Accession Version | XM_030252390.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3558bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | synaptopodin-2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAAGGCA TAACGGACTC TCTGCACTTG CTTGTTAAAA GACCCTCTAG TGGAACAAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030108250.1 |
CDS | 195..3752 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGAAGGCA TAACGGACTC TCTGCACTTG CTTGTTAAAA GACCCTCTAG TGGAACAAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09663 | |
Clone ID Related Accession (Same CDS sequence) | NM_080451.2 | |
Accession Version | NM_080451.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-20 | |
Organism | Mus musculus(house mouse) | |
Product | synaptopodin-2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC121315.14 and AC121540.14. On or before Apr 19, 2009 this sequence version replaced XM_915986.2, XM_619958.3, NM_080451.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC158045.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164133 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCACCG GAGATTTCAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_536699.2 |
CDS | 143..3916 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCACCG GAGATTTCAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu31576 | |
Clone ID Related Accession (Same CDS sequence) | XM_006500925.2 , XM_006500925.3 | |
Accession Version | XM_006500925.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3237bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | synaptopodin-2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006500925.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCACCG GAGATTTCAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006500988.1 |
CDS | 163..3399 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCACCG GAGATTTCAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
High-throughput discovery of novel developmental phenotypes. |
Regulation of smooth muscle dystrophin and synaptopodin 2 expression by actin polymerization and vascular injury. |
Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. |
Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes. |
Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3. |