Gene Symbol | Rhoc |
Entrez Gene ID | 11853 |
Full Name | ras homolog family member C |
Synonyms | AI324259,Arh9,Arhc |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Rhoc cDNA ORF clone
Gene Symbol | Rhoc |
Entrez Gene ID | 11853 |
Full Name | ras homolog family member C |
Synonyms | AI324259,Arh9,Arhc |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_007484.2 | NP_031510.2 | rho-related GTP-binding protein RhoC precursor |
NM_001291859.1 | NP_001278788.1 | rho-related GTP-binding protein RhoC precursor |
Canis lupus familiaris (dog) | RHOC | XP_540336.2 |
Danio rerio (zebrafish) | rhoad | NP_001002445.1 |
Danio rerio (zebrafish) | rhoac | NP_998515.1 |
Danio rerio (zebrafish) | rhoae | NP_957444.1 |
Bos taurus (cattle) | RHOC | NP_001039603.1 |
Xenopus tropicalis (tropical clawed frog) | rhoc | NP_001016569.1 |
Homo sapiens (human) | RHOC | NP_001036143.1 |
Pan troglodytes (chimpanzee) | RHOC | XP_003339043.1 |
Mus musculus (house mouse) | Rhoc | NP_031510.2 |
Rattus norvegicus (Norway rat) | Rhoc | NP_001099931.1 |
Gallus gallus (chicken) | RHOC | NP_001025020.1 |
Danio rerio (zebrafish) | rhoaa | NP_998302.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005160 | XP_001688510.1 |
Caenorhabditis elegans (roundworm) | rho-1 | NP_502959.1 |
Eremothecium gossypii | AGOS_ABR182W | NP_983130.1 |
Drosophila melanogaster (fruit fly) | Rho1 | NP_995851.1 |
RhoC regulates the actin remodeling required for phagosome formation during Fc?R-mediated phagocytosis.
Egami Y, Kawai K, Araki N
Journal of cell science130(24)4168-4179(2017 Dec)
Kctd13 deletion reduces synaptic transmission via increased RhoA.
Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, L?pez-Garc?a IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM
Nature551(7679)227-231(2017 Nov)
Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.
Zhao B, Wu Z, M?ller U
eLife5(2016 06)
The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
Ray JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J
Immunity43(4)690-702(2015 Oct)
Loss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice.
Zandvakili I, Davis AK, Hu G, Zheng Y
PloS one10(6)e0127923(2015)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
RhoC co-localizes with Fam65b in stereocilia and regulates Fam65b oligomerization what is critical for hair cell function.
Title: Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.
Inhibition of ovarian epithelial carcinoma tumorigenesis and progression by miR106b proceeds through the RhoC pathway.
Title: Inhibition of Ovarian Epithelial Carcinoma Tumorigenesis and Progression by microRNA 106b Mediated through the RhoC Pathway.
RHOC and RAB38 are dispensable for osteoclast function.
Title: The collection of NFATc1-dependent transcripts in the osteoclast includes numerous genes non-essential to physiologic bone resorption.
A p27(kip1)-binding protein, p27RF-Rho, promotes cancer metastasis via activation of RhoA and RhoC.
Title: A p27(kip1)-binding protein, p27RF-Rho, promotes cancer metastasis via activation of RhoA and RhoC.
We found that both RhoA and RhoC, but not RhoB, were required for initiation of centrosome duplication, and overactivation of RhoA, as well as RhoC, but not RhoB, promoted centrosome duplication and centrosome amplification.
Title: RhoA and RhoC are both required for the ROCK II-dependent promotion of centrosome duplication.
The following Rhoc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rhoc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu19093 | |
Clone ID Related Accession (Same CDS sequence) | NM_007484.2 , NM_001291859.1 | |
Accession Version | NM_007484.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | rho-related GTP-binding protein RhoC precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY147599.1, AK160650.1 and AI324259.1. On Nov 16, 2007 this sequence version replaced NM_007484.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK011599.1, AK152802.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTGCGA TCCGAAAGAA GCTGGTGATT GTGGGTGACG GTGCCTGTGG GAAGACCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_031510.2 |
CDS | 59..640 |
Translation |
Target ORF information:
Target ORF information:
|
NM_007484.2 |
1 | ATGGCTGCGA TCCGAAAGAA GCTGGTGATT GTGGGTGACG GTGCCTGTGG GAAGACCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu19093 | |
Clone ID Related Accession (Same CDS sequence) | NM_007484.2 , NM_001291859.1 | |
Accession Version | NM_001291859.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-24 | |
Organism | Mus musculus(house mouse) | |
Product | rho-related GTP-binding protein RhoC precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY315470.1, CX223083.1 and CO044736.1. On May 3, 2014 this sequence version replaced XM_006500929.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU510772.1, CB945668.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCTGCGA TCCGAAAGAA GCTGGTGATT GTGGGTGACG GTGCCTGTGG GAAGACCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001278788.1 |
CDS | 77..658 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001291859.1 |
1 | ATGGCTGCGA TCCGAAAGAA GCTGGTGATT GTGGGTGACG GTGCCTGTGG GAAGACCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RhoC regulates the actin remodeling required for phagosome formation during Fc?R-mediated phagocytosis. |
Kctd13 deletion reduces synaptic transmission via increased RhoA. |
Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function. |
The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. |
Loss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice. |