Chil3 cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Chil3 |
| Entrez Gene ID | 12655 |
| Full Name | chitinase-like 3 |
| Synonyms | AI505981,Chi3l3,ECF-L,Ym1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome | |
| Summary | The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is thought to function as a lectin and may be involved in inflammation and allergy. [provided by RefSeq, Sep 2015]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_009892.3 | NP_034022.2 | chitinase-like protein 3 precursor |
| Mus musculus (house mouse) | Chil3 | NP_034022.2 |
| Rattus norvegicus (Norway rat) | Chi3l3 | NP_001178641.1 |
| Mus musculus (house mouse) | Chil4 | NP_660108.2 |
Related articles in PubMed
First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment.
Saluzzo S, Gorki AD, Rana BMJ, Martins R, Scanlon S, Starkl P, Lakovits K, Hladik A, Korosec A, Sharif O, Warszawska JM, Jolin H, Mesteri I, McKenzie ANJ, Knapp S
Cell reports18(8)1893-1905(2017 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The soluble antigen from A. cantonensis could promote the Chil3 expression in macrophage and microglial cell lines induced by interleukin-13.
Title: Soluble antigen derived from IV larva of Angiostrongylus cantonensis promotes chitinase-like protein 3 (Chil3) expression induced by interleukin-13.
A significant increase of CHI3L3 mRNA expression was observed in the spinal cord of experimental autoimmune encephalitis mice compared to controls during the inflammatory phase.
Title: Breast regression protein-39 is not required for experimental autoimmune encephalomyelitis induction.
neutrophil-derived Ym1 protein uptake distinguishes wound macrophages in the absence of interleukin-4 signaling in murine wound healing
Title: Uptake of neutrophil-derived Ym1 protein distinguishes wound macrophages in the absence of interleukin-4 signaling in murine wound healing.
These results indicate that catalytically inactive BRP-39 and Ym1 are constitutive genes in normal mouse lung.
Title: Establishment of a quantitative PCR system for discriminating chitinase-like proteins: catalytically inactive breast regression protein-39 and Ym1 are constitutive genes in mouse lung.
These data indicate that helminth-induced immunomodulation occurs independently of changes in the microbiota but is dependent on Ym1.
Title: Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.
The following Chil3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Chil3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu14724 | |
| Clone ID Related Accession (Same CDS sequence) | NM_009892.3 | |
| Accession Version | NM_009892.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1197bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-30 | |
| Organism | Mus musculus(house mouse) | |
| Product | chitinase-like protein 3 precursor | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC125461.4 and AK137503.1. On Sep 15, 2015 this sequence version replaced NM_009892.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC061154.1, AK137503.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383, SAMN00849387 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCCAAGC TCATTCTTGT CACAGGTCTG GCAATTCTTC TGAACGTACA GCTGGGATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_034022.2 |
| CDS | 44..1240 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_009892.3 |
ORF Insert Sequence:
1 | ATGGCCAAGC TCATTCTTGT CACAGGTCTG GCAATTCTTC TGAACGTACA GCTGGGATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment. |