Gene Symbol | Cirbp |
Entrez Gene ID | 12696 |
Full Name | cold inducible RNA binding protein |
Synonyms | Cirp,R74941 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Cirbp cDNA ORF clone
Gene Symbol | Cirbp |
Entrez Gene ID | 12696 |
Full Name | cold inducible RNA binding protein |
Synonyms | Cirp,R74941 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006513164.2 | XP_006513227.1 | cold-inducible RNA-binding protein isoform X1 |
NM_007705.2 | NP_031731.1 | cold-inducible RNA-binding protein |
XM_030244855.1 | XP_030100715.1 | cold-inducible RNA-binding protein isoform X2 |
XM_006513164.1 | XP_006513227.1 | cold-inducible RNA-binding protein isoform X1 |
NM_007705.3 | NP_031731.1 | cold-inducible RNA-binding protein |
XM_006513165.1 | XP_006513228.1 | cold-inducible RNA-binding protein isoform X1 |
CIRBP | XP_002801048.1 | |
Rattus norvegicus (Norway rat) | Cirbp | NP_112409.2 |
Homo sapiens (human) | CIRBP | NP_001271.1 |
Gallus gallus (chicken) | CIRBP | NP_001026518.1 |
Danio rerio (zebrafish) | cirbpa | NP_001017797.1 |
Mus musculus (house mouse) | Cirbp | NP_031731.1 |
Pan troglodytes (chimpanzee) | CIRBP | XP_003953358.1 |
Canis lupus familiaris (dog) | CIRBP | XP_005633202.1 |
Bos taurus (cattle) | CIRBP | NP_001029450.1 |
Xenopus tropicalis (tropical clawed frog) | cirbp | NP_001017228.1 |
CIRP increases ICAM-1
Ode Y, Aziz M, Wang P
Journal of leukocyte biology(2018 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
this paper shows that cold air stimulation induced MUC5AC expression in wild-type mice but not in CIRP-/-) mice.
Title: Cold-inducible RNA-binding protein mediates cold air inducible airway mucin production through TLR4/NF-?B signaling pathway.
temperature-dependent accumulation of Cirbp mRNA is controlled primarily by the regulation of splicing efficiency, defined as the fraction of Cirbp pre-mRNA processed into mature mRNA
Title: Temperature regulates splicing efficiency of the cold-inducible RNA-binding protein gene Cirbp.
state. These data collectively suggest that a deficiency in CIRP accelerates the wound healing process
Title: A deficiency in cold-inducible RNA-binding protein accelerates the inflammation phase and improves wound healing.
These results can provide new insights into the molecular mechanisms of Cirp function.
Title: Analysis of gene expression profiles reveals the regulatory network of cold-inducible RNA-binding protein mediating the growth of BHK-21 cells.
Cirp appears to play a critical carcinogenic function and its expression might be a useful biomarker for hepatocellular carcinomas risk prediction.
Title: Cold-inducible RNA-binding protein promotes the development of liver cancer.
The following Cirbp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cirbp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu44167 | |
Clone ID Related Accession (Same CDS sequence) | XM_006513164.2 , XM_006513164.1 , XM_006513165.1 | |
Accession Version | XM_006513164.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | cold-inducible RNA-binding protein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCATCAG ATGAAGGCAA GCTTTTCGTG GGAGGACTCA GCTTCGACAC CAACGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006513227.1 |
CDS | 141..671 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006513164.1 |
1 | ATGGCATCAG ATGAAGGCAA GCTTTTCGTG GGAGGACTCA GCTTCGACAC CAACGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu44167 | |
Clone ID Related Accession (Same CDS sequence) | XM_006513164.2 , XM_006513164.1 , XM_006513165.1 | |
Accession Version | XM_006513165.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | cold-inducible RNA-binding protein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCATCAG ATGAAGGCAA GCTTTTCGTG GGAGGACTCA GCTTCGACAC CAACGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006513228.1 |
CDS | 94..624 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006513165.1 |
1 | ATGGCATCAG ATGAAGGCAA GCTTTTCGTG GGAGGACTCA GCTTCGACAC CAACGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu22744 | |
Clone ID Related Accession (Same CDS sequence) | NM_007705.2 , XM_030244855.1 , NM_007705.3 | |
Accession Version | NM_007705.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-04-14 | |
Organism | Mus musculus(House mouse) | |
Product | cold-inducible RNA-binding protein | |
Comment | PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC159999.6. On Mar 21, 2007 this sequence version replaced NM_007705.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D78135.1, AK014655.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCATCAG ATGAAGGCAA GCTTTTCGTG GGAGGACTCA GCTTCGACAC CAACGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_031731.1 |
CDS | 83..601 |
Translation |
Target ORF information:
Target ORF information:
|
NM_007705.2 |
1 | ATGGCATCAG ATGAAGGCAA GCTTTTCGTG GGAGGACTCA GCTTCGACAC CAACGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu22744 | |
Clone ID Related Accession (Same CDS sequence) | NM_007705.2 , XM_030244855.1 , NM_007705.3 | |
Accession Version | NM_007705.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Mus musculus(house mouse) | |
Product | cold-inducible RNA-binding protein | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK132584.1 and AI841072.1. On Dec 23, 2017 this sequence version replaced NM_007705.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC075699.1, AK014655.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCATCAG ATGAAGGCAA GCTTTTCGTG GGAGGACTCA GCTTCGACAC CAACGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_031731.1 |
CDS | 85..603 |
Translation |
Target ORF information:
Target ORF information:
|
NM_007705.3 |
1 | ATGGCATCAG ATGAAGGCAA GCTTTTCGTG GGAGGACTCA GCTTCGACAC CAACGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu22744 | |
Clone ID Related Accession (Same CDS sequence) | NM_007705.2 , XM_030244855.1 , NM_007705.3 | |
Accession Version | XM_030244855.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | cold-inducible RNA-binding protein isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCATCAG ATGAAGGCAA GCTTTTCGTG GGAGGACTCA GCTTCGACAC CAACGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030100715.1 |
CDS | 230..748 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030244855.1 |
1 | ATGGCATCAG ATGAAGGCAA GCTTTTCGTG GGAGGACTCA GCTTCGACAC CAACGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu44167 | |
Clone ID Related Accession (Same CDS sequence) | XM_006513164.2 , XM_006513164.1 , XM_006513165.1 | |
Accession Version | XM_006513164.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | cold-inducible RNA-binding protein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006513164.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCATCAG ATGAAGGCAA GCTTTTCGTG GGAGGACTCA GCTTCGACAC CAACGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006513227.1 |
CDS | 301..831 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006513164.2 |
1 | ATGGCATCAG ATGAAGGCAA GCTTTTCGTG GGAGGACTCA GCTTCGACAC CAACGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CIRP increases ICAM-1 |