Gene Symbol | Ccr10 |
Entrez Gene ID | 12777 |
Full Name | chemokine (C-C motif) receptor 10 |
Synonyms | Cmkbr9,Gpr2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Ccr10 cDNA ORF clone
Gene Symbol | Ccr10 |
Entrez Gene ID | 12777 |
Full Name | chemokine (C-C motif) receptor 10 |
Synonyms | Cmkbr9,Gpr2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_011248710.1 | XP_011247012.1 | C-C chemokine receptor type 10 isoform X1 |
NM_007721.4 | NP_031747.2 | C-C chemokine receptor type 10 |
Pan troglodytes (chimpanzee) | CCR10 | XP_001162702.1 |
Canis lupus familiaris (dog) | CCR10 | XP_849321.1 |
CCR10 | XP_001111554.1 | |
Bos taurus (cattle) | CCR10 | NP_001181893.1 |
Mus musculus (house mouse) | Ccr10 | NP_031747.2 |
Homo sapiens (human) | CCR10 | NP_057686.2 |
Rattus norvegicus (Norway rat) | Ccr10 | NP_001102306.1 |
Gallus gallus (chicken) | CCR10 | XP_004948677.1 |
Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation.
Zaid A, Hor JL, Christo SN, Groom JR, Heath WR, Mackay LK, Mueller SN
Journal of immunology (Baltimore, Md. : 1950)199(7)2451-2459(2017 Oct)
Axonal domain disorganization in Caspr1 and Caspr2 mutant myelinated axons affects neuromuscular junction integrity, leading to muscle atrophy.
Saifetiarova J, Liu X, Taylor AM, Li J, Bhat MA
Journal of neuroscience research95(7)1373-1390(2017 Jul)
Losartan and Dexamethasone may inhibit chemotaxis to reduce the infiltration of Th22 cells in IgA nephropathy.
Xiao C, Zhou Q, Li X, Li H, Zhong Y, Meng T, Zhu M, Sun H, Liu S, Tang R, Pu J, Xu Y, Xiao P
International immunopharmacology42203-208(2017 Jan)
Differential developmental requirement and peripheral regulation for dermal V?4 and V?6T17 cells in health and inflammation.
Cai Y, Xue F, Fleming C, Yang J, Ding C, Ma Y, Liu M, Zhang HG, Zheng J, Xiong N, Yan J
Nature communications53986(2014 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
this study shows that losartan and dexamethasone may suppress inflammatory responses in IgA nephropathy by inhibiting CCR10 expression in Th22 cells
Title: Losartan and Dexamethasone may inhibit chemotaxis to reduce the infiltration of Th22 cells in IgA nephropathy.
controls innate and memory immune responses in the skin
Title: CCR10 regulates balanced maintenance and function of resident regulatory and effector T cells to promote immune homeostasis in the skin.
Our in vivo analysis demonstrated that uniform expression of Ccr10 on MSCs and alteration of Ccl27 level in the skin enhance extravasation of stem cells from circulation and facilitate their migration within cutaneous tissue
Title: Analysis of chemotactic molecules in bone marrow-derived mesenchymal stem cells and the skin: Ccl27-Ccr10 axis as a basis for targeting to cutaneous tissues.
These findings provide definite evidence that CCR10 is important in skin intraepithelial Vgamma3(+) T lymphocyte development
Title: CCR10 is important for the development of skin-specific gammadeltaT cells by regulating their migration and location.
CCR10 is critical for efficient localization and accumulation of immunoglobulin A antibody-secreting cells to the lactating mammary gland.
Title: An indispensable role for the chemokine receptor CCR10 in IgA antibody-secreting cell accumulation.
The following Ccr10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ccr10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu00679 | |
Clone ID Related Accession (Same CDS sequence) | XM_011248710.1 , NM_007721.4 | |
Accession Version | NM_007721.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-22 | |
Organism | Mus musculus(house mouse) | |
Product | C-C chemokine receptor type 10 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK090044.1. On or before Sep 2, 2006 this sequence version replaced XM_894898.2, XM_905316.2, XM_983479.1, NM_007721.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK090044.1, AF215983.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGGACCA AGCCCACAGA GCAGGTCTCC TGGGGACTTT ACTCCGGGTA CGATGAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_031747.2 |
CDS | 21..1109 |
Translation |
Target ORF information:
Target ORF information:
|
NM_007721.4 |
1 | ATGGGGACCA AGCCCACAGA GCAGGTCTCC TGGGGACTTT ACTCCGGGTA CGATGAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00679 | |
Clone ID Related Accession (Same CDS sequence) | XM_011248710.1 , NM_007721.4 | |
Accession Version | XM_011248710.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-08 | |
Organism | Mus musculus(House mouse) | |
Product | C-C chemokine receptor type 10 isoform X1 | |
Comment |
1 | ATGGGGACCA AGCCCACAGA GCAGGTCTCC TGGGGACTTT ACTCCGGGTA CGATGAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011247012.1 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011248710.1 |
1 | ATGGGGACCA AGCCCACAGA GCAGGTCTCC TGGGGACTTT ACTCCGGGTA CGATGAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation. |
Axonal domain disorganization in Caspr1 and Caspr2 mutant myelinated axons affects neuromuscular junction integrity, leading to muscle atrophy. |
Losartan and Dexamethasone may inhibit chemotaxis to reduce the infiltration of Th22 cells in IgA nephropathy. |
Differential developmental requirement and peripheral regulation for dermal V?4 and V?6T17 cells in health and inflammation. |