Gene Symbol | Ddb1 |
Entrez Gene ID | 13194 |
Full Name | damage specific DNA binding protein 1 |
Synonyms | 127kDa,AA408517,p127-Ddb1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Ddb1 cDNA ORF clone
Gene Symbol | Ddb1 |
Entrez Gene ID | 13194 |
Full Name | damage specific DNA binding protein 1 |
Synonyms | 127kDa,AA408517,p127-Ddb1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006526639.3 | XP_006526702.1 | DNA damage-binding protein 1 isoform X1 |
XM_006526639.2 | XP_006526702.1 | DNA damage-binding protein 1 isoform X1 |
NM_015735.2 | NP_056550.1 | DNA damage-binding protein 1 |
NM_015735.1 | NP_056550.1 | DNA damage-binding protein 1 |
Mus musculus (house mouse) | Ddb1 | NP_056550.1 |
Rattus norvegicus (Norway rat) | Ddb1 | NP_741992.2 |
Danio rerio (zebrafish) | ddb1 | NP_956920.1 |
Xenopus tropicalis (tropical clawed frog) | ddb1 | XP_002937687.2 |
DDB1 | XP_001082958.2 | |
Canis lupus familiaris (dog) | DDB1 | XP_533275.2 |
Drosophila melanogaster (fruit fly) | pic | NP_650257.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002472 | XP_312466.2 |
Oryza sativa (rice) | Os05g0592400 | NP_001056495.1 |
Homo sapiens (human) | DDB1 | NP_001914.3 |
Pan troglodytes (chimpanzee) | DDB1 | XP_508472.4 |
Bos taurus (cattle) | DDB1 | NP_001073731.1 |
Gallus gallus (chicken) | DDB1 | NP_989547.1 |
Arabidopsis thaliana (thale cress) | DDB1A | NP_192451.1 |
Arabidopsis thaliana (thale cress) | DDB1B | NP_193842.1 |
DDB1-Mediated CRY1 Degradation Promotes FOXO1-Driven Gluconeogenesis in Liver.
Tong X, Zhang D, Charney N, Jin E, VanDommelen K, Stamper K, Gupta N, Saldate J, Yin L
Diabetes66(10)2571-2582(2017 10)
Sirtuin 7-dependent deacetylation of DDB1 regulates the expression of nuclear receptor TR4.
Karim MF, Yoshizawa T, Sobuz SU, Sato Y, Yamagata K
Biochemical and biophysical research communications490(2)423-428(2017 08)
CRL4
Li G, Ji T, Chen J, Fu Y, Hou L, Feng Y, Zhang T, Song T, Zhao J, Endo Y, Lin H, Cai X, Cang Y
Cell reports18(6)1499-1511(2017 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
SIRT7 inhibits TR4 degradation by deacetylation of DDB1.
Title: Sirtuin 7-dependent deacetylation of DDB1 regulates the expression of nuclear receptor TR4.
These studies identify CUL4-DDB1 complex as a novel post-translational regulator of stem and progenitor maintenance and differentiation.
Title: The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis.
uncovered a novel biological role for CUL4A-DDB1-CDT2 E3 ligase that regulates molecular circadian behaviors via promoting ubiquitination-dependent degradation of CRY1
Title: CUL4-DDB1-CDT2 E3 Ligase Regulates the Molecular Clock Activity by Promoting Ubiquitination-Dependent Degradation of the Mammalian CRY1.
UCH-L1 disrupts a complex between the DDB1-CUL4 ubiquitin ligase complex.
Title: Ubiquitin hydrolase UCH-L1 destabilizes mTOR complex 1 by antagonizing DDB1-CUL4-mediated ubiquitination of raptor.
In a constructive process, pM27 recruits DDB1 to exploit ubiquitin ligase complexes catalyzing the obstruction of the STAT2-dependent antiviral state of cells to permit viral replication.
Title: Identification of DNA-damage DNA-binding protein 1 as a conditional essential factor for cytomegalovirus replication in interferon-?-stimulated cells.
The following Ddb1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ddb1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu21775 | |
Clone ID Related Accession (Same CDS sequence) | NM_015735.2 , NM_015735.1 | |
Accession Version | NM_015735.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3423bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-23 | |
Organism | Mus musculus(house mouse) | |
Product | DNA damage-binding protein 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC125093.4, AB026432.1 and AC132247.3. On Jul 21, 2018 this sequence version replaced NM_015735.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7974084.27621.1, AK155020.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCGTACA ACTACGTCGT AACGGCGCAG AAGCCTACTG CAGTGAACGG CTGTGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_056550.1 |
CDS | 110..3532 |
Translation |
Target ORF information:
Target ORF information:
|
NM_015735.2 |
1 | ATGTCGTACA ACTACGTCGT AACGGCGCAG AAGCCTACTG CAGTGAACGG CTGTGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21775 | |
Clone ID Related Accession (Same CDS sequence) | NM_015735.2 , NM_015735.1 | |
Accession Version | NM_015735.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3423bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-12-16 | |
Organism | Mus musculus(house mouse) | |
Product | DNA damage-binding protein 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB026432.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB026432.1, AK154303.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCGTACA ACTACGTCGT AACGGCGCAG AAGCCTACTG CAGTGAACGG CTGTGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_056550.1 |
CDS | 82..3504 |
Translation |
Target ORF information:
Target ORF information:
|
NM_015735.1 |
1 | ATGTCGTACA ACTACGTCGT AACGGCGCAG AAGCCTACTG CAGTGAACGG CTGTGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu55227 | |
Clone ID Related Accession (Same CDS sequence) | XM_006526639.3 , XM_006526639.2 | |
Accession Version | XM_006526639.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3459bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | DNA damage-binding protein 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006526639.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCGTACA ACTACGTCGT AACGGCGCAG AAGCCTACTG CAGTGAACGG CTGTGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006526702.1 |
CDS | 139..3597 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006526639.3 |
1 | ATGTCGTACA ACTACGTCGT AACGGCGCAG AAGCCTACTG CAGTGAACGG CTGTGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu55227 | |
Clone ID Related Accession (Same CDS sequence) | XM_006526639.3 , XM_006526639.2 | |
Accession Version | XM_006526639.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3459bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | DNA damage-binding protein 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006526639.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCGTACA ACTACGTCGT AACGGCGCAG AAGCCTACTG CAGTGAACGG CTGTGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006526702.1 |
CDS | 215..3673 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006526639.2 |
1 | ATGTCGTACA ACTACGTCGT AACGGCGCAG AAGCCTACTG CAGTGAACGG CTGTGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
DDB1-Mediated CRY1 Degradation Promotes FOXO1-Driven Gluconeogenesis in Liver. |
Sirtuin 7-dependent deacetylation of DDB1 regulates the expression of nuclear receptor TR4. |
CRL4 |