Gene Symbol | Dhcr7 |
Entrez Gene ID | 13360 |
Full Name | 7-dehydrocholesterol reductase |
Synonyms | AA409147 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Dhcr7 cDNA ORF clone
Gene Symbol | Dhcr7 |
Entrez Gene ID | 13360 |
Full Name | 7-dehydrocholesterol reductase |
Synonyms | AA409147 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006508479.4 | XP_006508542.1 | 7-dehydrocholesterol reductase isoform X3 |
XM_006508476.3 | XP_006508539.2 | 7-dehydrocholesterol reductase isoform X1 |
XM_006508480.2 | XP_006508543.1 | 7-dehydrocholesterol reductase isoform X2 |
XM_006508481.2 | XP_006508544.1 | 7-dehydrocholesterol reductase isoform X2 |
XM_030242076.1 | XP_030097936.1 | 7-dehydrocholesterol reductase isoform X4 |
XM_006508479.3 | XP_006508542.1 | 7-dehydrocholesterol reductase isoform X2 |
XM_030242075.1 | XP_030097935.1 | 7-dehydrocholesterol reductase isoform X2 |
XM_006508481.3 | XP_006508544.1 | 7-dehydrocholesterol reductase isoform X3 |
XM_011241979.2 | XP_011240281.1 | 7-dehydrocholesterol reductase isoform X4 |
XM_011241979.1 | XP_011240281.1 | 7-dehydrocholesterol reductase isoform X3 |
XM_006508476.4 | XP_006508539.2 | 7-dehydrocholesterol reductase isoform X1 |
XM_006508478.1 | XP_006508541.1 | 7-dehydrocholesterol reductase isoform X3 |
XM_006508480.3 | XP_006508543.1 | 7-dehydrocholesterol reductase isoform X3 |
NM_007856.2 | NP_031882.1 | 7-dehydrocholesterol reductase |
Mus musculus (house mouse) | Dhcr7 | NP_031882.1 |
Arabidopsis thaliana (thale cress) | DWF5 | NP_175460.1 |
Bos taurus (cattle) | DHCR7 | NP_001014927.1 |
Rattus norvegicus (Norway rat) | Dhcr7 | NP_071784.1 |
Gallus gallus (chicken) | DHCR7 | NP_001186419.1 |
Danio rerio (zebrafish) | dhcr7 | NP_958487.1 |
Xenopus tropicalis (tropical clawed frog) | dhcr7 | NP_989235.1 |
Homo sapiens (human) | DHCR7 | NP_001157289.1 |
Canis lupus familiaris (dog) | DHCR7 | XP_005631421.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_03765 | XP_003720123.1 |
Oryza sativa (rice) | Os02g0465400 | NP_001046809.1 |
Pan troglodytes (chimpanzee) | DHCR7 | XP_001174206.1 |
Oxidative stress, serotonergic changes and decreased ultrasonic vocalizations in a mouse model of Smith-Lemli-Opitz syndrome.
Sharif NF, Korade Z, Porter NA, Harrison FE
Genes, brain, and behavior16(6)619-626(2017 Jul)
7-dehydrocholesterol efficiently supports Ret signaling in a mouse model of Smith-Opitz-Lemli syndrome.
Gou-F?bregas M, Maci? A, Anerillas C, Vaquero M, Jov? M, Jain S, Ribera J, Encinas M
Scientific reports628534(2016 Jun)
Reduced cholesterol levels impair Smoothened activation in Smith-Lemli-Opitz syndrome.
Blassberg R, Macrae JI, Briscoe J, Jacob J
Human molecular genetics25(4)693-705(2016 Feb)
Dhcr7 Regulates Palatal Shelf Fusion through Regulation of Shh and Bmp2 Expression.
Xiao WL, Zhang DZ, Xu H, Zhuang CZ
BioMed research international20167532714(2016)
A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo.
?i?ecio?lu M, Budak H, Geffers L, ?ankaya M, ?iftci M, Thaller C, Eichele G, K?frevio?lu ??, ?zdemir H
Journal of lipid research56(8)1551-9(2015 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Dhcr7 heterozygous mice made fewer ultrasonic vocalizations. Increases of 7-DHC and expression of the serotonin transporter were observed in the compound mutant mice.
Title: Oxidative stress, serotonergic changes and decreased ultrasonic vocalizations in a mouse model of Smith-Lemli-Opitz syndrome.
Studied the effect of 7-dehydrocholesterol reductase (Dhcr7) and identified signal pathways involved in regulation of embryonic palatogenesis. Expression changes of Dhcr7, Sonic Hedgehog (Shh), and bone morphogenetic protein-2 (Bmp2) were measured by RT-PCR and WB after Dhcr7 gene silencing and the addition of exogenous cholesterol.
Title: Dhcr7 Regulates Palatal Shelf Fusion through Regulation of Shh and Bmp2 Expression.
significant increases in Col1a1, serine/threonine-protein kinase 1, Ctnnb1, CSRNP1, Ddit4, Cyp2e1, and Krit1 expressions and great decreases inreceptor D2, Neu1, and Dhcr7 expressions following long-term exposure to TiO2 NPs
Title: Neurotoxicity and gene-expressed profile in brain-injured mice caused by exposure to titanium dioxide nanoparticles.
data indicate an underlying dysfunction of the 5-HT2A receptors in Dhcr7-HET mice that warrants further investigation to establish how this may relate to behavioral disturbances in human patients carrying Dhcr7 mutations
Title: Behavioral and serotonergic response changes in the Dhcr7-HET mouse model of Smith-Lemli-Opitz syndrome.
conclude that cytochrome P450 reductase is not involved in 7-dehydrocholesterol reductase activity
Title: 7-Dehydrocholesterol reductase activity is independent of cytochrome P450 reductase.
The following Dhcr7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dhcr7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu21697 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508479.4 , XM_006508480.2 , XM_006508481.2 , XM_006508479.3 , XM_006508481.3 , XM_006508478.1 , XM_006508480.3 , NM_007856.2 | |
Accession Version | NM_007856.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-03 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC133502.4 and AF057368.1. On or before Dec 7, 2005 this sequence version replaced XM_918231.1, XM_925568.1, NM_007856.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AF057368.1, BC006854.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_031882.1 |
CDS | 508..1923 |
Translation |
Target ORF information:
Target ORF information:
|
NM_007856.2 |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21697 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508479.4 , XM_006508480.2 , XM_006508481.2 , XM_006508479.3 , XM_006508481.3 , XM_006508478.1 , XM_006508480.3 , NM_007856.2 | |
Accession Version | XM_006508480.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006508480.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006508543.1 |
CDS | 32..1447 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006508480.2 |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21697 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508479.4 , XM_006508480.2 , XM_006508481.2 , XM_006508479.3 , XM_006508481.3 , XM_006508478.1 , XM_006508480.3 , NM_007856.2 | |
Accession Version | XM_006508481.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006508481.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006508544.1 |
CDS | 32..1447 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006508481.2 |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21697 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508479.4 , XM_006508480.2 , XM_006508481.2 , XM_006508479.3 , XM_006508481.3 , XM_006508478.1 , XM_006508480.3 , NM_007856.2 | |
Accession Version | XM_006508479.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006508479.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006508542.1 |
CDS | 69..1484 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006508479.3 |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21697 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508479.4 , XM_006508480.2 , XM_006508481.2 , XM_006508479.3 , XM_006508481.3 , XM_006508478.1 , XM_006508480.3 , NM_007856.2 | |
Accession Version | XM_006508478.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006508541.1 |
CDS | 243..1658 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006508478.1 |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67528 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508476.3 , XM_006508476.4 | |
Accession Version | XM_006508476.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1425bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006508476.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCCTGA TGGCTTCGAA ATCCCAGCAC AACGCTCCCA AAGTCAAGAG TCCCAACGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006508539.2 |
CDS | 99..1523 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006508476.3 |
1 | ATGGGCCTGA TGGCTTCGAA ATCCCAGCAC AACGCTCCCA AAGTCAAGAG TCCCAACGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67529 | |
Clone ID Related Accession (Same CDS sequence) | XM_030242076.1 , XM_011241979.2 , XM_011241979.1 | |
Accession Version | XM_011241979.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCCGT GCCTGGTGCT GCTTTATTCC TGGCTTCCTG ACTTCTGCCA CAGATTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011240281.1 |
CDS | 574..1695 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011241979.1 |
1 | ATGGGGCCGT GCCTGGTGCT GCTTTATTCC TGGCTTCCTG ACTTCTGCCA CAGATTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21697 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508479.4 , XM_006508480.2 , XM_006508481.2 , XM_006508479.3 , XM_006508481.3 , XM_006508478.1 , XM_006508480.3 , NM_007856.2 | |
Accession Version | XM_006508479.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006508479.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006508542.1 |
CDS | 164..1579 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006508479.4 |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21697 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508479.4 , XM_006508480.2 , XM_006508481.2 , XM_006508479.3 , XM_006508481.3 , XM_006508478.1 , XM_006508480.3 , NM_007856.2 | |
Accession Version | XM_006508481.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006508481.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006508544.1 |
CDS | 130..1545 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006508481.3 |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21697 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508479.4 , XM_006508480.2 , XM_006508481.2 , XM_006508479.3 , XM_006508481.3 , XM_006508478.1 , XM_006508480.3 , NM_007856.2 | |
Accession Version | XM_006508480.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006508480.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006508543.1 |
CDS | 32..1447 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006508480.3 |
1 | ATGGCTTCGA AATCCCAGCA CAACGCTCCC AAAGTCAAGA GTCCCAACGG CAAGGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67528 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508476.3 , XM_006508476.4 | |
Accession Version | XM_006508476.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1425bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006508476.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCCTGA TGGCTTCGAA ATCCCAGCAC AACGCTCCCA AAGTCAAGAG TCCCAACGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006508539.2 |
CDS | 96..1520 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006508476.4 |
1 | ATGGGCCTGA TGGCTTCGAA ATCCCAGCAC AACGCTCCCA AAGTCAAGAG TCCCAACGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67529 | |
Clone ID Related Accession (Same CDS sequence) | XM_030242076.1 , XM_011241979.2 , XM_011241979.1 | |
Accession Version | XM_030242076.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCCGT GCCTGGTGCT GCTTTATTCC TGGCTTCCTG ACTTCTGCCA CAGATTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030097936.1 |
CDS | 246..1367 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030242076.1 |
1 | ATGGGGCCGT GCCTGGTGCT GCTTTATTCC TGGCTTCCTG ACTTCTGCCA CAGATTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67529 | |
Clone ID Related Accession (Same CDS sequence) | XM_030242076.1 , XM_011241979.2 , XM_011241979.1 | |
Accession Version | XM_011241979.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011241979.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCCGT GCCTGGTGCT GCTTTATTCC TGGCTTCCTG ACTTCTGCCA CAGATTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011240281.1 |
CDS | 574..1695 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011241979.2 |
1 | ATGGGGCCGT GCCTGGTGCT GCTTTATTCC TGGCTTCCTG ACTTCTGCCA CAGATTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu89343 | |
Clone ID Related Accession (Same CDS sequence) | XM_030242075.1 | |
Accession Version | XM_030242075.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1563bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | 7-dehydrocholesterol reductase isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTCTCCT TCAGGACGCA GCTCGCGAAA TCCACTTCCG ATTGGTCGTC TGTGACCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030097935.1 |
CDS | 207..1769 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030242075.1 |
1 | ATGCTCTCCT TCAGGACGCA GCTCGCGAAA TCCACTTCCG ATTGGTCGTC TGTGACCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Oxidative stress, serotonergic changes and decreased ultrasonic vocalizations in a mouse model of Smith-Lemli-Opitz syndrome. |
7-dehydrocholesterol efficiently supports Ret signaling in a mouse model of Smith-Opitz-Lemli syndrome. |
Reduced cholesterol levels impair Smoothened activation in Smith-Lemli-Opitz syndrome. |
Dhcr7 Regulates Palatal Shelf Fusion through Regulation of Shh and Bmp2 Expression. |
A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo. |