Gene Symbol | Drd3 |
Entrez Gene ID | 13490 |
Full Name | dopamine receptor D3 |
Synonyms | D3R |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Drd3 cDNA ORF clone
gRNAs
Gene Symbol | Drd3 |
Entrez Gene ID | 13490 |
Full Name | dopamine receptor D3 |
Synonyms | D3R |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_007877.2 | NP_031903.1 | D(3) dopamine receptor |
XM_006521777.2 | XP_006521840.1 | D(3) dopamine receptor isoform X1 |
XM_006521777.3 | XP_006521840.1 | D(3) dopamine receptor isoform X1 |
Homo sapiens (human) | DRD3 | NP_000787.2 |
Bos taurus (cattle) | DRD3 | NP_001179824.1 |
Mus musculus (house mouse) | Drd3 | NP_031903.1 |
Gallus gallus (chicken) | DRD3 | XP_004938262.1 |
Danio rerio (zebrafish) | drd3 | NP_898890.1 |
Pan troglodytes (chimpanzee) | DRD3 | NP_001029084.1 |
Canis lupus familiaris (dog) | DRD3 | XP_545106.3 |
Rattus norvegicus (Norway rat) | Drd3 | NP_058836.1 |
Caenorhabditis elegans (roundworm) | dop-2 | NP_001256127.1 |
Drd3 Signaling in the Lateral Septum Mediates Early Life Stress-Induced Social Dysfunction.
Shin S, Pribiag H, Lilascharoen V, Knowland D, Wang XY, Lim BK
Neuron97(1)195-208.e6(2018 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The D3 dopamine receptor, a member of the Gi-coupled D2 family of dopamine receptors, are expressed throughout limbic circuits, including prefrontal cortex (PFC).
Title: D3 Receptors Regulate Excitability in a Unique Class of Prefrontal Pyramidal Cells.
Dopamine Receptor Signaling in MIN6 beta-Cells
Title: Dopamine Receptor Signaling in MIN6 ?-Cells Revealed by Fluorescence Fluctuation Spectroscopy.
this study shows that D3R regulates the effect of methamphetamine on LPS-induced mast cells activation
Title: The effects of D3R on TLR4 signaling involved in the regulation of METH-mediated mast cells activation.
this study shows that DRD3 signaling evokes suppressor of cytokine signaling 5 expression, a negative regulator of Th2 development, which indirectly favors acquisition of Th1 phenotype
Title: Dopamine Receptor D3 Signaling on CD4+ T Cells Favors Th1- and Th17-Mediated Immunity.
This study show the Genetic blockade of the dopamine D3 receptor enhances hippocampal expression of PACAP and receptors and alters their cortical distribution.
Title: Genetic blockade of the dopamine D3 receptor enhances hippocampal expression of PACAP and receptors and alters their cortical distribution.
The following Drd3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Drd3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu51860 | |
Clone ID Related Accession (Same CDS sequence) | XM_006521777.2 , XM_006521777.3 | |
Accession Version | XM_006521777.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1437bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | D(3) dopamine receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006521777.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTCAG GAACTGAGGC GCTAAACACC ACAGTCTCCA GGCACCAGAA GAAATTTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006521840.1 |
CDS | 194..1630 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCTTCAG GAACTGAGGC GCTAAACACC ACAGTCTCCA GGCACCAGAA GAAATTTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu76895 | |
Clone ID Related Accession (Same CDS sequence) | NM_007877.2 | |
Accession Version | NM_007877.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1341bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-09 | |
Organism | Mus musculus(house mouse) | |
Product | D(3) dopamine receptor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC137819.1. On Nov 21, 2015 this sequence version replaced NM_007877.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC119286.1, X67274.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCACCTC TGAGCCAGAT AAGCAGCCAC ATCAACTCCA CCTGTGGGGC AGAAAACTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_031903.1 |
CDS | 22..1362 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCACCTC TGAGCCAGAT AAGCAGCCAC ATCAACTCCA CCTGTGGGGC AGAAAACTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu51860 | |
Clone ID Related Accession (Same CDS sequence) | XM_006521777.2 , XM_006521777.3 | |
Accession Version | XM_006521777.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1437bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | D(3) dopamine receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006521777.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTCAG GAACTGAGGC GCTAAACACC ACAGTCTCCA GGCACCAGAA GAAATTTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006521840.1 |
CDS | 194..1630 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTTCAG GAACTGAGGC GCTAAACACC ACAGTCTCCA GGCACCAGAA GAAATTTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Drd3 Signaling in the Lateral Septum Mediates Early Life Stress-Induced Social Dysfunction. |