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Srsf10 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Srsf10
Entrez Gene ID 14105
Full Name serine/arginine-rich splicing factor 10
Synonyms FUSIP2,Fusip1,NSSR1,NSSR2,Nssr,SRrp40,Sfrs13a,Srsf13a,TASR,TASR1,TASR2
General protein information
Preferred Names

serine/arginine-rich splicing factor 10

Names

serine/arginine-rich splicing factor 10
FUS-interacting serine-arginine-rich protein 1
Fus-associated protein with serine-arginine repeats
TLS-associated SR protein
TLS-associated protein with SR repeats
TLS-associated protein with Ser-Arg repeats
TLS-associated serine-arginine protein
neural-salient serine/arginine-rich protein
neural-specific SR protein
serine/arginine-rich splicing factor 13A
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

4

4|4 D3

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_011250188.1 XP_011248490.1 serine/arginine-rich splicing factor 10 isoform X1
XM_011250188.2 XP_011248490.1 serine/arginine-rich splicing factor 10 isoform X1
NM_001284195.1 NP_001271124.1 serine/arginine-rich splicing factor 10 isoform 3
NM_001080387.2 NP_001073856.1 serine/arginine-rich splicing factor 10 isoform 2
NM_001284196.1 NP_001271125.1 serine/arginine-rich splicing factor 10 isoform 4
NM_010178.3 NP_034308.1 serine/arginine-rich splicing factor 10 isoform 1

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) SFRS13A XP_003307925.1
Mus musculus (house mouse) Srsf10 NP_001073856.1
Xenopus tropicalis (tropical clawed frog) srsf10 NP_001011096.1
Homo sapiens (human) SRSF10 NP_473357.1
Canis lupus familiaris (dog) SRSF10 XP_003638945.1
Gallus gallus (chicken) SRSF10 NP_001026077.1

Gene Ontology


Bibliography

Related articles in PubMed

SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing.
Wei N, Cheng Y, Wang Z, Liu Y, Luo C, Liu L, Chen L, Xie Z, Lu Y, Feng Y
Cell reports13(8)1647-57(2015 Nov)

Splicing factor NSSR1 reduces neuronal injury after mouse transient global cerebral ischemia.
Qi Y, Li Y, Cui SC, Zhao JJ, Liu XY, Ji CX, Sun FY, Xu P, Chen XH
Glia63(5)826-45(2015 May)

SRSF10 regulates alternative splicing and is required for adipocyte differentiation.
Li H, Cheng Y, Wu W, Liu Y, Wei N, Feng X, Xie Z, Feng Y
Molecular and cellular biology34(12)2198-207(2014 Jun)

Dephosphorylation of NSSR1 regulates alternative splicing of the GluR-B minigene.
Zhang W, Li LL, Chen XH, Peng ZY
Genetics and molecular research : GMR13(1)1753-63(2014 Mar)

The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.
Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H
PloS one8(10)e75754(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SRSF10 represses inclusion of PGC1alpha exon 7a.
Title: SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing.

The results of this study suggested for the first time that NSSR1 may provide a novel mechanism for reducing neuronal injury after ischemia, probably through regulation on alternative splicing of NCAM-L1 and CREB in astrocytes.
Title: Splicing factor NSSR1 reduces neuronal injury after mouse transient global cerebral ischemia.

These results identify SRSF10 as an essential regulator for adipocyte differentiation.
Title: SRSF10 regulates alternative splicing and is required for adipocyte differentiation.

We further show that an SRSRSK sequence in the RS3 domain may play an important role in the function of NSSR1 in pre-mRNA splicing.
Title: Dephosphorylation of NSSR1 regulates alternative splicing of the GluR-B minigene.

NSSR1 mRNA was expressed in mouse cerebrum, cerebellum, heart, liver, intestine, kidney and lung tissue, but NSSR1 protein was only expressed in neural tissues.
Title: [Expression of neural salient serine-/arginine-rich protein 1 (NSSR1) in colorectal cancer].

The following Srsf10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Srsf10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu05677 NM_010178.3
Latest version!		 Mus musculus serine and arginine-rich splicing factor 10 (Srsf10), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OMu16981 NM_001284195.1
Latest version!		 Mus musculus serine and arginine-rich splicing factor 10 (Srsf10), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OMu17191 NM_001284196.1
Latest version!		 Mus musculus serine and arginine-rich splicing factor 10 (Srsf10), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OMu01394 NM_001080387.2
Latest version!		 Mus musculus serine and arginine-rich splicing factor 10 (Srsf10), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $139.30
$199.00
OMu67721 XM_011250188.2
Latest version!		 Mus musculus serine/arginine-rich splicing factor 10 (Srsf10), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $139.30
$199.00
View Old Accession Versions >>
OMu67721 XM_011250188.1 Mus musculus serine/arginine-rich splicing factor 10 (Srsf10), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu05677
Clone ID Related Accession (Same CDS sequence) NM_010178.3
Accession Version NM_010178.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 552bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-10-14
Organism Mus musculus(house mouse)
Product serine/arginine-rich splicing factor 10 isoform 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY244789.1, BY717856.1, AK168558.1, AK168571.1, AK030968.1 and AF042383.1. On Sep 26, 2013 this sequence version replaced NM_010178.2. Transcript Variant: This variant (1) contains an alternate 3' terminal exon compared to variant 2. It encodes isoform 1, which is shorter and has a distinct C-terminus, compared to isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
ATGTCCCGAT ACCTGCGCCC CCCTAACACG TCTCTGTTCG TCAGGAACGT GGCGGACGAC 
ACCAGGTCTG AAGATTTACG TCGGGAATTT GGTCGTTATG GTCCAATAGT AGATGTTTAT 
GTCCCACTTG ATTTCTACAC TCGGCGTCCA AGAGGATTTG CATATGTTCA ATTTGAGGAT 
GTTCGTGATG CTGAAGACGC TTTACATAAT TTGGACAGAA AATGGATTTG TGGGCGTCAG 
ATTGAAATCC AGTTCGCACA GGGGGATCGG AAGACACCAA ATCAAATGAA AGCCAAGGAA 
GGGAGGAATG TATACAGCTC TTCACGATAT GACGATTATG ACCGATATAG ACGCTCTCGA 
AGCCGGAGTT ATGAAAGGAG AAGATCGAGG AGTCGCTCCT TTGATTATAA CTATAGGAGA 
TCTTACAGTC CTAGAAACAG TAGACCGACT GGAAGACCAC GGCGTAGCCG AAGCCATTCC 
GACAATGATA GACCAAACTG CAGCTGGAAT ACCCAGTACA GTTCTGCTTA CTACACTTCA 
AGAAAGATCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_034308.1
CDS157..708
Translation

Target ORF information:

RefSeq Version NM_010178.3
Organism Mus musculus(house mouse)
Definition Mus musculus serine and arginine-rich splicing factor 10 (Srsf10), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_010178.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGTCCCGAT ACCTGCGCCC CCCTAACACG TCTCTGTTCG TCAGGAACGT GGCGGACGAC 
ACCAGGTCTG AAGATTTACG TCGGGAATTT GGTCGTTATG GTCCAATAGT AGATGTTTAT 
GTCCCACTTG ATTTCTACAC TCGGCGTCCA AGAGGATTTG CATATGTTCA ATTTGAGGAT 
GTTCGTGATG CTGAAGACGC TTTACATAAT TTGGACAGAA AATGGATTTG TGGGCGTCAG 
ATTGAAATCC AGTTCGCACA GGGGGATCGG AAGACACCAA ATCAAATGAA AGCCAAGGAA 
GGGAGGAATG TATACAGCTC TTCACGATAT GACGATTATG ACCGATATAG ACGCTCTCGA 
AGCCGGAGTT ATGAAAGGAG AAGATCGAGG AGTCGCTCCT TTGATTATAA CTATAGGAGA 
TCTTACAGTC CTAGAAACAG TAGACCGACT GGAAGACCAC GGCGTAGCCG AAGCCATTCC 
GACAATGATA GACCAAACTG CAGCTGGAAT ACCCAGTACA GTTCTGCTTA CTACACTTCA 
AGAAAGATCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu16981
Clone ID Related Accession (Same CDS sequence) NM_001284195.1
Accession Version NM_001284195.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 786bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-10-14
Organism Mus musculus(house mouse)
Product serine/arginine-rich splicing factor 10 isoform 3
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY244789.1, BY717856.1, CF914989.1, CN528501.1, AK168524.1 and BC043060.1. Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 3' coding region, compared to variant 2. It encodes isoform 3, which is shorter than isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTCCCGAT ACCTGCGCCC CCCTAACACG TCTCTGTTCG TCAGGAACGT GGCGGACGAC 
ACCAGGTCTG AAGATTTACG TCGGGAATTT GGTCGTTATG GTCCAATAGT AGATGTTTAT 
GTCCCACTTG ATTTCTACAC TCGGCGTCCA AGAGGATTTG CATATGTTCA ATTTGAGGAT 
GTTCGTGATG CTGAAGACGC TTTACATAAT TTGGACAGAA AATGGATTTG TGGGCGTCAG 
ATTGAAATCC AGTTCGCACA GGGGGATCGG AAGACACCAA ATCAAATGAA AGCCAAGGAA 
GGGAGGAATG TATACAGCTC TTCACGATAT GACGATTATG ACCGATATAG ACGCTCTCGA 
AGCCGGAGTT ATGAAAGGAG AAGATCGAGG AGTCGCTCCT TTGATTATAA CTATAGGAGA 
TCTTACAGTC CTAGAAATAG ACCGACTGGA AGACCACGGC GTAGCCGAAG CCATTCCGAC 
AATGATAGAT TCAAACACCG AAATCGATCT TTTTCAAGAT CTAAATCCAA TTCAAGATCA 
CGGTCCAAGT CCCAGCCCAA GAAAGAAATG AAGGCTAAAT CACGTTCTAG GTCTGCATCT 
CACACCAAAA CTAGAGGCAC CTCTAAAACA GATTCCAAAA CACATTATAA GTCTGGCTCA 
AGATATGAAA AGGAATCAAG GAAAAAAGAA CCACCTAGAT CCAAATCTCA GTCAAGATCA 
CAGTCTAGGT CTAGGTCAAA ATCTAGGTCA AGGTCTTGGA CTAGTCCCAA GTCCAGTGGC 
CACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001271124.1
CDS157..942
Translation

Target ORF information:

RefSeq Version NM_001284195.1
Organism Mus musculus(house mouse)
Definition Mus musculus serine and arginine-rich splicing factor 10 (Srsf10), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001284195.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTCCCGAT ACCTGCGCCC CCCTAACACG TCTCTGTTCG TCAGGAACGT GGCGGACGAC 
ACCAGGTCTG AAGATTTACG TCGGGAATTT GGTCGTTATG GTCCAATAGT AGATGTTTAT 
GTCCCACTTG ATTTCTACAC TCGGCGTCCA AGAGGATTTG CATATGTTCA ATTTGAGGAT 
GTTCGTGATG CTGAAGACGC TTTACATAAT TTGGACAGAA AATGGATTTG TGGGCGTCAG 
ATTGAAATCC AGTTCGCACA GGGGGATCGG AAGACACCAA ATCAAATGAA AGCCAAGGAA 
GGGAGGAATG TATACAGCTC TTCACGATAT GACGATTATG ACCGATATAG ACGCTCTCGA 
AGCCGGAGTT ATGAAAGGAG AAGATCGAGG AGTCGCTCCT TTGATTATAA CTATAGGAGA 
TCTTACAGTC CTAGAAATAG ACCGACTGGA AGACCACGGC GTAGCCGAAG CCATTCCGAC 
AATGATAGAT TCAAACACCG AAATCGATCT TTTTCAAGAT CTAAATCCAA TTCAAGATCA 
CGGTCCAAGT CCCAGCCCAA GAAAGAAATG AAGGCTAAAT CACGTTCTAG GTCTGCATCT 
CACACCAAAA CTAGAGGCAC CTCTAAAACA GATTCCAAAA CACATTATAA GTCTGGCTCA 
AGATATGAAA AGGAATCAAG GAAAAAAGAA CCACCTAGAT CCAAATCTCA GTCAAGATCA 
CAGTCTAGGT CTAGGTCAAA ATCTAGGTCA AGGTCTTGGA CTAGTCCCAA GTCCAGTGGC 
CACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu17191
Clone ID Related Accession (Same CDS sequence) NM_001284196.1
Accession Version NM_001284196.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 549bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-10-14
Organism Mus musculus(house mouse)
Product serine/arginine-rich splicing factor 10 isoform 4
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY244789.1, BY717856.1, AK169071.1, AK030968.1, AK168571.1 and AF042383.1. Transcript Variant: This variant (4) uses an alternate in-frame splice site in the 3' coding region and contains an alternate 3' terminal exon, compared to variant 2. It encodes isoform 4, which is shorter and has a distinct C-terminus, compared to isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
ATGTCCCGAT ACCTGCGCCC CCCTAACACG TCTCTGTTCG TCAGGAACGT GGCGGACGAC 
ACCAGGTCTG AAGATTTACG TCGGGAATTT GGTCGTTATG GTCCAATAGT AGATGTTTAT 
GTCCCACTTG ATTTCTACAC TCGGCGTCCA AGAGGATTTG CATATGTTCA ATTTGAGGAT 
GTTCGTGATG CTGAAGACGC TTTACATAAT TTGGACAGAA AATGGATTTG TGGGCGTCAG 
ATTGAAATCC AGTTCGCACA GGGGGATCGG AAGACACCAA ATCAAATGAA AGCCAAGGAA 
GGGAGGAATG TATACAGCTC TTCACGATAT GACGATTATG ACCGATATAG ACGCTCTCGA 
AGCCGGAGTT ATGAAAGGAG AAGATCGAGG AGTCGCTCCT TTGATTATAA CTATAGGAGA 
TCTTACAGTC CTAGAAATAG ACCGACTGGA AGACCACGGC GTAGCCGAAG CCATTCCGAC 
AATGATAGAC CAAACTGCAG CTGGAATACC CAGTACAGTT CTGCTTACTA CACTTCAAGA 
AAGATCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001271125.1
CDS157..705
Translation

Target ORF information:

RefSeq Version NM_001284196.1
Organism Mus musculus(house mouse)
Definition Mus musculus serine and arginine-rich splicing factor 10 (Srsf10), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001284196.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGTCCCGAT ACCTGCGCCC CCCTAACACG TCTCTGTTCG TCAGGAACGT GGCGGACGAC 
ACCAGGTCTG AAGATTTACG TCGGGAATTT GGTCGTTATG GTCCAATAGT AGATGTTTAT 
GTCCCACTTG ATTTCTACAC TCGGCGTCCA AGAGGATTTG CATATGTTCA ATTTGAGGAT 
GTTCGTGATG CTGAAGACGC TTTACATAAT TTGGACAGAA AATGGATTTG TGGGCGTCAG 
ATTGAAATCC AGTTCGCACA GGGGGATCGG AAGACACCAA ATCAAATGAA AGCCAAGGAA 
GGGAGGAATG TATACAGCTC TTCACGATAT GACGATTATG ACCGATATAG ACGCTCTCGA 
AGCCGGAGTT ATGAAAGGAG AAGATCGAGG AGTCGCTCCT TTGATTATAA CTATAGGAGA 
TCTTACAGTC CTAGAAATAG ACCGACTGGA AGACCACGGC GTAGCCGAAG CCATTCCGAC 
AATGATAGAC CAAACTGCAG CTGGAATACC CAGTACAGTT CTGCTTACTA CACTTCAAGA 
AAGATCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu67721
Clone ID Related Accession (Same CDS sequence) XM_011250188.1 , XM_011250188.2
Accession Version XM_011250188.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 654bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product serine/arginine-rich splicing factor 10 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
ATGTCCCGAT ACCTGCGCCC CCCTAACACG TCTCTGTTCG TCAGGAACGT GGCGGACGAC 
ACCAGGTCTG AAGATTTACG TCGGGAATTT GGTCGTTATG GTCCAATAGT AGATGTTTAT 
GTCCCACTTG ATTTCTACAC TCGGCGTCCA AGAGGATTTG CATATGTTCA ATTTGAGGAT 
GTTCGTGATG CTGAAGACGC TTTACATAAT TTGGACAGAA AATGGATTTG TGGGCGTCAG 
ATTGAAATCC AGTTCGCACA GGGGGATCGG AAGACACCAA ATCAAATGAA AGCCAAGGAA 
GGGAGGAATG TATACAGCTC TTCACGATAT GACGATTATG ACCGATATAG ACGCTCTCGA 
AGCCGGAGTT ATGAAAGGAG AAGATCGAGG AGTCGCTCCT TTGATTATAA CTATAGGAGA 
TCTTACAGTC CTAGAAACAG TAGACCGACT GGAAGACCAC GGCGTAGCCG AAGCCATTCC 
GACAATGATA GATTCAAACA CCGAAATCGA TCTTTTTCAA GATCTAAATC CAATTCAAGA 
TCACGGTCCA AGTCCCAGCC CAAGAAAGAA ATGAAGGCTA AATCACGTTC TAGACCAAAC 
TGCAGCTGGA ATACCCAGTA CAGTTCTGCT TACTACACTT CAAGAAAGAT CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011248490.1
CDS500..1153
Translation

Target ORF information:

RefSeq Version XM_011250188.1
Organism Mus musculus(house mouse)
Definition Mus musculus serine/arginine-rich splicing factor 10 (Srsf10), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011250188.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGTCCCGAT ACCTGCGCCC CCCTAACACG TCTCTGTTCG TCAGGAACGT GGCGGACGAC 
ACCAGGTCTG AAGATTTACG TCGGGAATTT GGTCGTTATG GTCCAATAGT AGATGTTTAT 
GTCCCACTTG ATTTCTACAC TCGGCGTCCA AGAGGATTTG CATATGTTCA ATTTGAGGAT 
GTTCGTGATG CTGAAGACGC TTTACATAAT TTGGACAGAA AATGGATTTG TGGGCGTCAG 
ATTGAAATCC AGTTCGCACA GGGGGATCGG AAGACACCAA ATCAAATGAA AGCCAAGGAA 
GGGAGGAATG TATACAGCTC TTCACGATAT GACGATTATG ACCGATATAG ACGCTCTCGA 
AGCCGGAGTT ATGAAAGGAG AAGATCGAGG AGTCGCTCCT TTGATTATAA CTATAGGAGA 
TCTTACAGTC CTAGAAACAG TAGACCGACT GGAAGACCAC GGCGTAGCCG AAGCCATTCC 
GACAATGATA GATTCAAACA CCGAAATCGA TCTTTTTCAA GATCTAAATC CAATTCAAGA 
TCACGGTCCA AGTCCCAGCC CAAGAAAGAA ATGAAGGCTA AATCACGTTC TAGACCAAAC 
TGCAGCTGGA ATACCCAGTA CAGTTCTGCT TACTACACTT CAAGAAAGAT CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu01394
Clone ID Related Accession (Same CDS sequence) NM_001080387.2
Accession Version NM_001080387.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 789bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-10-14
Organism Mus musculus(house mouse)
Product serine/arginine-rich splicing factor 10 isoform 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY244789.1, BY717856.1, AK168558.1 and BC043060.1. On Sep 26, 2013 this sequence version replaced NM_001080387.1. Transcript Variant: This variant (2) encodes the longest isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTCCCGAT ACCTGCGCCC CCCTAACACG TCTCTGTTCG TCAGGAACGT GGCGGACGAC 
ACCAGGTCTG AAGATTTACG TCGGGAATTT GGTCGTTATG GTCCAATAGT AGATGTTTAT 
GTCCCACTTG ATTTCTACAC TCGGCGTCCA AGAGGATTTG CATATGTTCA ATTTGAGGAT 
GTTCGTGATG CTGAAGACGC TTTACATAAT TTGGACAGAA AATGGATTTG TGGGCGTCAG 
ATTGAAATCC AGTTCGCACA GGGGGATCGG AAGACACCAA ATCAAATGAA AGCCAAGGAA 
GGGAGGAATG TATACAGCTC TTCACGATAT GACGATTATG ACCGATATAG ACGCTCTCGA 
AGCCGGAGTT ATGAAAGGAG AAGATCGAGG AGTCGCTCCT TTGATTATAA CTATAGGAGA 
TCTTACAGTC CTAGAAACAG TAGACCGACT GGAAGACCAC GGCGTAGCCG AAGCCATTCC 
GACAATGATA GATTCAAACA CCGAAATCGA TCTTTTTCAA GATCTAAATC CAATTCAAGA 
TCACGGTCCA AGTCCCAGCC CAAGAAAGAA ATGAAGGCTA AATCACGTTC TAGGTCTGCA 
TCTCACACCA AAACTAGAGG CACCTCTAAA ACAGATTCCA AAACACATTA TAAGTCTGGC 
TCAAGATATG AAAAGGAATC AAGGAAAAAA GAACCACCTA GATCCAAATC TCAGTCAAGA 
TCACAGTCTA GGTCTAGGTC AAAATCTAGG TCAAGGTCTT GGACTAGTCC CAAGTCCAGT 
GGCCACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001073856.1
CDS157..945
Translation

Target ORF information:

RefSeq Version NM_001080387.2
Organism Mus musculus(house mouse)
Definition Mus musculus serine and arginine-rich splicing factor 10 (Srsf10), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001080387.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTCCCGAT ACCTGCGCCC CCCTAACACG TCTCTGTTCG TCAGGAACGT GGCGGACGAC 
ACCAGGTCTG AAGATTTACG TCGGGAATTT GGTCGTTATG GTCCAATAGT AGATGTTTAT 
GTCCCACTTG ATTTCTACAC TCGGCGTCCA AGAGGATTTG CATATGTTCA ATTTGAGGAT 
GTTCGTGATG CTGAAGACGC TTTACATAAT TTGGACAGAA AATGGATTTG TGGGCGTCAG 
ATTGAAATCC AGTTCGCACA GGGGGATCGG AAGACACCAA ATCAAATGAA AGCCAAGGAA 
GGGAGGAATG TATACAGCTC TTCACGATAT GACGATTATG ACCGATATAG ACGCTCTCGA 
AGCCGGAGTT ATGAAAGGAG AAGATCGAGG AGTCGCTCCT TTGATTATAA CTATAGGAGA 
TCTTACAGTC CTAGAAACAG TAGACCGACT GGAAGACCAC GGCGTAGCCG AAGCCATTCC 
GACAATGATA GATTCAAACA CCGAAATCGA TCTTTTTCAA GATCTAAATC CAATTCAAGA 
TCACGGTCCA AGTCCCAGCC CAAGAAAGAA ATGAAGGCTA AATCACGTTC TAGGTCTGCA 
TCTCACACCA AAACTAGAGG CACCTCTAAA ACAGATTCCA AAACACATTA TAAGTCTGGC 
TCAAGATATG AAAAGGAATC AAGGAAAAAA GAACCACCTA GATCCAAATC TCAGTCAAGA 
TCACAGTCTA GGTCTAGGTC AAAATCTAGG TCAAGGTCTT GGACTAGTCC CAAGTCCAGT 
GGCCACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu67721
Clone ID Related Accession (Same CDS sequence) XM_011250188.1 , XM_011250188.2
Accession Version XM_011250188.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 654bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product serine/arginine-rich splicing factor 10 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011250188.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
ATGTCCCGAT ACCTGCGCCC CCCTAACACG TCTCTGTTCG TCAGGAACGT GGCGGACGAC 
ACCAGGTCTG AAGATTTACG TCGGGAATTT GGTCGTTATG GTCCAATAGT AGATGTTTAT 
GTCCCACTTG ATTTCTACAC TCGGCGTCCA AGAGGATTTG CATATGTTCA ATTTGAGGAT 
GTTCGTGATG CTGAAGACGC TTTACATAAT TTGGACAGAA AATGGATTTG TGGGCGTCAG 
ATTGAAATCC AGTTCGCACA GGGGGATCGG AAGACACCAA ATCAAATGAA AGCCAAGGAA 
GGGAGGAATG TATACAGCTC TTCACGATAT GACGATTATG ACCGATATAG ACGCTCTCGA 
AGCCGGAGTT ATGAAAGGAG AAGATCGAGG AGTCGCTCCT TTGATTATAA CTATAGGAGA 
TCTTACAGTC CTAGAAACAG TAGACCGACT GGAAGACCAC GGCGTAGCCG AAGCCATTCC 
GACAATGATA GATTCAAACA CCGAAATCGA TCTTTTTCAA GATCTAAATC CAATTCAAGA 
TCACGGTCCA AGTCCCAGCC CAAGAAAGAA ATGAAGGCTA AATCACGTTC TAGACCAAAC 
TGCAGCTGGA ATACCCAGTA CAGTTCTGCT TACTACACTT CAAGAAAGAT CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011248490.1
CDS476..1129
Translation

Target ORF information:

RefSeq Version XM_011250188.2
Organism Mus musculus(house mouse)
Definition Mus musculus serine/arginine-rich splicing factor 10 (Srsf10), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011250188.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGTCCCGAT ACCTGCGCCC CCCTAACACG TCTCTGTTCG TCAGGAACGT GGCGGACGAC 
ACCAGGTCTG AAGATTTACG TCGGGAATTT GGTCGTTATG GTCCAATAGT AGATGTTTAT 
GTCCCACTTG ATTTCTACAC TCGGCGTCCA AGAGGATTTG CATATGTTCA ATTTGAGGAT 
GTTCGTGATG CTGAAGACGC TTTACATAAT TTGGACAGAA AATGGATTTG TGGGCGTCAG 
ATTGAAATCC AGTTCGCACA GGGGGATCGG AAGACACCAA ATCAAATGAA AGCCAAGGAA 
GGGAGGAATG TATACAGCTC TTCACGATAT GACGATTATG ACCGATATAG ACGCTCTCGA 
AGCCGGAGTT ATGAAAGGAG AAGATCGAGG AGTCGCTCCT TTGATTATAA CTATAGGAGA 
TCTTACAGTC CTAGAAACAG TAGACCGACT GGAAGACCAC GGCGTAGCCG AAGCCATTCC 
GACAATGATA GATTCAAACA CCGAAATCGA TCTTTTTCAA GATCTAAATC CAATTCAAGA 
TCACGGTCCA AGTCCCAGCC CAAGAAAGAA ATGAAGGCTA AATCACGTTC TAGACCAAAC 
TGCAGCTGGA ATACCCAGTA CAGTTCTGCT TACTACACTT CAAGAAAGAT CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing.
Cell reports13(8)1647-57(2015 Nov)
Wei N,Cheng Y,Wang Z,Liu Y,Luo C,Liu L,Chen L,Xie Z,Lu Y,Feng Y


book

Splicing factor NSSR1 reduces neuronal injury after mouse transient global cerebral ischemia.
Glia63(5)826-45(2015 May)
Qi Y,Li Y,Cui SC,Zhao JJ,Liu XY,Ji CX,Sun FY,Xu P,Chen XH


book

SRSF10 regulates alternative splicing and is required for adipocyte differentiation.
Molecular and cellular biology34(12)2198-207(2014 Jun)
Li H,Cheng Y,Wu W,Liu Y,Wei N,Feng X,Xie Z,Feng Y


book

Dephosphorylation of NSSR1 regulates alternative splicing of the GluR-B minigene.
Genetics and molecular research : GMR13(1)1753-63(2014 Mar)
Zhang W,Li LL,Chen XH,Peng ZY


book

The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.
PloS one8(10)e75754(2013)
Shimizu H,Kubo A,Uchibe K,Hashimoto M,Yokoyama S,Takada S,Mitsuoka K,Asahara H