Fbp2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fbp2
Entrez Gene ID	14120
Full Name	fructose bisphosphatase 2
Synonyms	Fbp-1,Fbp1,Rae-30
General protein information	Preferred Names fructose bisphosphatase 2 Names fructose-1,6-bisphosphatase isozyme 2 D-fructose-1,6-bisphosphate 1-phosphohydrolase 2 FBPase 2 FBPase muscle muscle FBPase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 B3

mRNA and Protein(s)

mRNA	Protein	Name
NM_007994.3	NP_032020.2	fructose-1,6-bisphosphatase isozyme 2
NM_007994.4	NP_032020.2	fructose-1,6-bisphosphatase isozyme 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	FBP2	XP_533504.2
Mus musculus (house mouse)	Fbp2	NP_032020.2
Drosophila melanogaster (fruit fly)	fbp	NP_724223.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009173	XP_319937.4
Arabidopsis thaliana (thale cress)	AT1G43670	NP_175032.1
Pan troglodytes (chimpanzee)	FBP2	XP_520718.2
Danio rerio (zebrafish)	fbp2	NP_001004008.1
Bos taurus (cattle)	FBP2	NP_001039629.1
Homo sapiens (human)	FBP2	NP_003828.2
Rattus norvegicus (Norway rat)	Fbp2	NP_446168.1
	FBP2	XP_002800246.1
Gallus gallus (chicken)	FBP2	XP_425039.1
Caenorhabditis elegans (roundworm)	fbp-1	NP_491004.1
Oryza sativa (rice)	Os01g0866400	NP_001044906.1
Xenopus tropicalis (tropical clawed frog)	fbp2	NP_001027516.1

Gene Ontology
Bibliography

Related articles in PubMed

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J, Stein F, Schultz C, Sauer U, Aulehla A
Developmental cell40(4)331-341.e4(2017 02)

Nur77 deletion impairs muscle growth during developmental myogenesis and muscle regeneration in mice.
Cortez-Toledo O, Schnair C, Sangngern P, Metzger D, Chao LC
PloS one12(2)e0171268(2017)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Bowman CE, Zhao L, Hartung T, Wolfgang MJ
Molecular and cellular biology36(15)2089-104(2016 Aug)

An Ideal PPAR Response Element Bound to and Activated by PPAR?.
Tzeng J, Byun J, Park JY, Yamamoto T, Schesing K, Tian B, Sadoshima J, Oka S
PloS one10(8)e0134996(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that binding and activation of glucokinase by PFK-2/FBPase-2 in beta-cells is promoted by glucose, resulting in an enhancement of insulin secretion at stimulatory glucose concentrations, without affecting basal insulin secretion.
Title: Endogenous activation of glucokinase by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase is glucose dependent.

The following Fbp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fbp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu01195	NM_007994.4 Latest version!	Mus musculus fructose bisphosphatase 2 (Fbp2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
View Old Accession Versions >>
OMu01195	NM_007994.3	Mus musculus fructose bisphosphatase 2 (Fbp2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fbp2 ( NM_007994.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032020.2 Mus musculus fructose bisphosphatase 2 (Fbp2), mRNA.

Price & Availability↑

CloneID	OMu01195
Clone ID Related Accession (Same CDS sequence)	NM_007994.3 , NM_007994.4
Accession Version	NM_007994.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1020bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-09
Organism	Mus musculus(house mouse)
Product	fructose-1,6-bisphosphatase isozyme 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK166898.1. On Apr 6, 2007 this sequence version replaced NM_007994.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK166898.1, AK146946.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN01164134 [ECO:0000348] ##Evidence-Data-END##

ATGACGGACA GAAGCCCCTT TGAGACAGAC ATGCTGACCC TGACCCGTTA CGTTATGGAA 
AAGGGGCGAC AGGCCAAAGG GACCGGAGAA CTCACCCAGC TGCTCAACTC GATGCTGACT 
GCCATCAAAG CCATCTCTTC CGCAGTGCGC AAGGCCGGCC TGGCCAACCT GTATGGGATT 
TCGGGGAGCG TGAATGTGAC AGGAGATGAG GTGAAGAAAC TGGACGTGCT GTCCAACTCC 
CTGGTCATCA ACATGCTTCA GTCCTCCTAC AGCACCTGTG TGCTCGTCTC CGAAGAGAAT 
AAAGAGGCGG TGATCACAGC CCAGGAGAGG AGGGGGAAAT ATGTGGTTTG CTTTGACCCT 
CTGGATGGAT CTTCAAACAT TGACTGCCTG GCCTCCATCG GAACTATATT TGCTATTTAC 
AGAAAGACCA CGGAGGATGA GCCTTCTGAG AAGGATGCCT TGCAGCCTGG CCGCAACATC 
GTGGCTGCGG GTTATGCACT GTATGGTAGT GCAACCCTGG TCGCTCTTTC CACAGGACAA 
GGAGTAGATC TCTTCATGCT GGACCCGGCT CTTGGAGAAT TCGTGCTAGT GGAAAAAGAT 
GTCCGGATTA AGAAGAAAGG GAAAATTTTT AGCCTCAACG AGGGCTATGC CAAGTATTTT 
GATGCTGCTA CTGCTGAGTA TGTACAGAAA AAGAAATTCC CCGAGGATGG CAGTGAGCCT 
TATGGAGCCA GGTACGTGGG TTCCATGGTG GCTGATGTGC ATCGCACCTT GGTCTATGGA 
GGAATCTTCA TGTACCCAGC CAACCAGAAG AGTCCTAATG GCAAGCTCCG GCTCCTGTAT 
GAATGCAATC CTGTGGCCTA TATCATCGAG CAAGCAGGAG GTATGGCAAC CACAGGCACC 
CAGCCAGTAC TGGATGTGAA ACCTGAGAGT ATTCACCAGC GAGTCCCCCT CATTCTGGGG 
TCCCCTGAGG ATGTGCAAGA GTATCTCAGC TGTGTGCAGA GAAACCAGGC AGGCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032020.2
CDS	74..1093
Translation	MTDRSPFETDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLANLYGISGSVNVTGDEVKKLDVLSNSLVINMLQSSYSTCVLVSEENKEAVITAQERRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTTEDEPSEKDALQPGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVRIKKKGKIFSLNEGYAKYFDAATAEYVQKKKFPEDGSEPYGARYVGSMVADVHRTLVYGGIFMYPANQKSPNGKLRLLYECNPVAYIIEQAGGMATTGTQPVLDVKPESIHQRVPLILGSPEDVQEYLSCVQRNQAGR

Target ORF information:

RefSeq Version	NM_007994.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus fructose bisphosphatase 2 (Fbp2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007994.3

ORF Insert Sequence:

ATGACGGACA GAAGCCCCTT TGAGACAGAC ATGCTGACCC TGACCCGTTA CGTTATGGAA 
AAGGGGCGAC AGGCCAAAGG GACCGGAGAA CTCACCCAGC TGCTCAACTC GATGCTGACT 
GCCATCAAAG CCATCTCTTC CGCAGTGCGC AAGGCCGGCC TGGCCAACCT GTATGGGATT 
TCGGGGAGCG TGAATGTGAC AGGAGATGAG GTGAAGAAAC TGGACGTGCT GTCCAACTCC 
CTGGTCATCA ACATGCTTCA GTCCTCCTAC AGCACCTGTG TGCTCGTCTC CGAAGAGAAT 
AAAGAGGCGG TGATCACAGC CCAGGAGAGG AGGGGGAAAT ATGTGGTTTG CTTTGACCCT 
CTGGATGGAT CTTCAAACAT TGACTGCCTG GCCTCCATCG GAACTATATT TGCTATTTAC 
AGAAAGACCA CGGAGGATGA GCCTTCTGAG AAGGATGCCT TGCAGCCTGG CCGCAACATC 
GTGGCTGCGG GTTATGCACT GTATGGTAGT GCAACCCTGG TCGCTCTTTC CACAGGACAA 
GGAGTAGATC TCTTCATGCT GGACCCGGCT CTTGGAGAAT TCGTGCTAGT GGAAAAAGAT 
GTCCGGATTA AGAAGAAAGG GAAAATTTTT AGCCTCAACG AGGGCTATGC CAAGTATTTT 
GATGCTGCTA CTGCTGAGTA TGTACAGAAA AAGAAATTCC CCGAGGATGG CAGTGAGCCT 
TATGGAGCCA GGTACGTGGG TTCCATGGTG GCTGATGTGC ATCGCACCTT GGTCTATGGA 
GGAATCTTCA TGTACCCAGC CAACCAGAAG AGTCCTAATG GCAAGCTCCG GCTCCTGTAT 
GAATGCAATC CTGTGGCCTA TATCATCGAG CAAGCAGGAG GTATGGCAAC CACAGGCACC 
CAGCCAGTAC TGGATGTGAA ACCTGAGAGT ATTCACCAGC GAGTCCCCCT CATTCTGGGG 
TCCCCTGAGG ATGTGCAAGA GTATCTCAGC TGTGTGCAGA GAAACCAGGC AGGCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fbp2 ( NM_007994.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032020.2 Mus musculus fructose bisphosphatase 2 (Fbp2), mRNA.

Price & Availability↑

CloneID	OMu01195
Clone ID Related Accession (Same CDS sequence)	NM_007994.3 , NM_007994.4
Accession Version	NM_007994.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1020bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Mus musculus(house mouse)
Product	fructose-1,6-bisphosphatase isozyme 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK146946.1. On Feb 4, 2019 this sequence version replaced NM_007994.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK168374.1, AK146946.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN01164134 [ECO:0000348] ##Evidence-Data-END##

ATGACGGACA GAAGCCCCTT TGAGACAGAC ATGCTGACCC TGACCCGTTA CGTTATGGAA 
AAGGGGCGAC AGGCCAAAGG GACCGGAGAA CTCACCCAGC TGCTCAACTC GATGCTGACT 
GCCATCAAAG CCATCTCTTC CGCAGTGCGC AAGGCCGGCC TGGCCAACCT GTATGGGATT 
TCGGGGAGCG TGAATGTGAC AGGAGATGAG GTGAAGAAAC TGGACGTGCT GTCCAACTCC 
CTGGTCATCA ACATGCTTCA GTCCTCCTAC AGCACCTGTG TGCTCGTCTC CGAAGAGAAT 
AAAGAGGCGG TGATCACAGC CCAGGAGAGG AGGGGGAAAT ATGTGGTTTG CTTTGACCCT 
CTGGATGGAT CTTCAAACAT TGACTGCCTG GCCTCCATCG GAACTATATT TGCTATTTAC 
AGAAAGACCA CGGAGGATGA GCCTTCTGAG AAGGATGCCT TGCAGCCTGG CCGCAACATC 
GTGGCTGCGG GTTATGCACT GTATGGTAGT GCAACCCTGG TCGCTCTTTC CACAGGACAA 
GGAGTAGATC TCTTCATGCT GGACCCGGCT CTTGGAGAAT TCGTGCTAGT GGAAAAAGAT 
GTCCGGATTA AGAAGAAAGG GAAAATTTTT AGCCTCAACG AGGGCTATGC CAAGTATTTT 
GATGCTGCTA CTGCTGAGTA TGTACAGAAA AAGAAATTCC CCGAGGATGG CAGTGAGCCT 
TATGGAGCCA GGTACGTGGG TTCCATGGTG GCTGATGTGC ATCGCACCTT GGTCTATGGA 
GGAATCTTCA TGTACCCAGC CAACCAGAAG AGTCCTAATG GCAAGCTCCG GCTCCTGTAT 
GAATGCAATC CTGTGGCCTA TATCATCGAG CAAGCAGGAG GTATGGCAAC CACAGGCACC 
CAGCCAGTAC TGGATGTGAA ACCTGAGAGT ATTCACCAGC GAGTCCCCCT CATTCTGGGG 
TCCCCTGAGG ATGTGCAAGA GTATCTCAGC TGTGTGCAGA GAAACCAGGC AGGCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032020.2
CDS	104..1123
Translation	MTDRSPFETDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLANLYGISGSVNVTGDEVKKLDVLSNSLVINMLQSSYSTCVLVSEENKEAVITAQERRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTTEDEPSEKDALQPGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVRIKKKGKIFSLNEGYAKYFDAATAEYVQKKKFPEDGSEPYGARYVGSMVADVHRTLVYGGIFMYPANQKSPNGKLRLLYECNPVAYIIEQAGGMATTGTQPVLDVKPESIHQRVPLILGSPEDVQEYLSCVQRNQAGR

Target ORF information:

RefSeq Version	NM_007994.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus fructose bisphosphatase 2 (Fbp2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007994.4

ORF Insert Sequence:

ATGACGGACA GAAGCCCCTT TGAGACAGAC ATGCTGACCC TGACCCGTTA CGTTATGGAA 
AAGGGGCGAC AGGCCAAAGG GACCGGAGAA CTCACCCAGC TGCTCAACTC GATGCTGACT 
GCCATCAAAG CCATCTCTTC CGCAGTGCGC AAGGCCGGCC TGGCCAACCT GTATGGGATT 
TCGGGGAGCG TGAATGTGAC AGGAGATGAG GTGAAGAAAC TGGACGTGCT GTCCAACTCC 
CTGGTCATCA ACATGCTTCA GTCCTCCTAC AGCACCTGTG TGCTCGTCTC CGAAGAGAAT 
AAAGAGGCGG TGATCACAGC CCAGGAGAGG AGGGGGAAAT ATGTGGTTTG CTTTGACCCT 
CTGGATGGAT CTTCAAACAT TGACTGCCTG GCCTCCATCG GAACTATATT TGCTATTTAC 
AGAAAGACCA CGGAGGATGA GCCTTCTGAG AAGGATGCCT TGCAGCCTGG CCGCAACATC 
GTGGCTGCGG GTTATGCACT GTATGGTAGT GCAACCCTGG TCGCTCTTTC CACAGGACAA 
GGAGTAGATC TCTTCATGCT GGACCCGGCT CTTGGAGAAT TCGTGCTAGT GGAAAAAGAT 
GTCCGGATTA AGAAGAAAGG GAAAATTTTT AGCCTCAACG AGGGCTATGC CAAGTATTTT 
GATGCTGCTA CTGCTGAGTA TGTACAGAAA AAGAAATTCC CCGAGGATGG CAGTGAGCCT 
TATGGAGCCA GGTACGTGGG TTCCATGGTG GCTGATGTGC ATCGCACCTT GGTCTATGGA 
GGAATCTTCA TGTACCCAGC CAACCAGAAG AGTCCTAATG GCAAGCTCCG GCTCCTGTAT 
GAATGCAATC CTGTGGCCTA TATCATCGAG CAAGCAGGAG GTATGGCAAC CACAGGCACC 
CAGCCAGTAC TGGATGTGAA ACCTGAGAGT ATTCACCAGC GAGTCCCCCT CATTCTGGGG 
TCCCCTGAGG ATGTGCAAGA GTATCTCAGC TGTGTGCAGA GAAACCAGGC AGGCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Developmental cell40(4)331-341.e4(2017 02)
Bulusu V,Prior N,Snaebjornsson MT,Kuehne A,Sonnen KF,Kress J,Stein F,Schultz C,Sauer U,Aulehla A

Nur77 deletion impairs muscle growth during developmental myogenesis and muscle regeneration in mice.
PloS one12(2)e0171268(2017)
Cortez-Toledo O,Schnair C,Sangngern P,Metzger D,Chao LC

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Molecular and cellular biology36(15)2089-104(2016 Aug)
Bowman CE,Zhao L,Hartung T,Wolfgang MJ

An Ideal PPAR Response Element Bound to and Activated by PPAR?.
PloS one10(8)e0134996(2015)
Tzeng J,Byun J,Park JY,Yamamoto T,Schesing K,Tian B,Sadoshima J,Oka S

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Fbp2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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