Gene Symbol | Fmo3 |
Entrez Gene ID | 14262 |
Full Name | flavin containing monooxygenase 3 |
Synonyms | AW111792 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Fmo3 cDNA ORF clone
gRNAs
Gene Symbol | Fmo3 |
Entrez Gene ID | 14262 |
Full Name | flavin containing monooxygenase 3 |
Synonyms | AW111792 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_008030.2 | NP_032056.1 | dimethylaniline monooxygenase [N-oxide-forming] 3 |
Homo sapiens (human) | FMO3 | NP_001002294.1 |
Xenopus tropicalis (tropical clawed frog) | fmo3 | NP_001015707.1 |
Canis lupus familiaris (dog) | FMO3 | NP_001003060.1 |
Mus musculus (house mouse) | Fmo3 | NP_032056.1 |
Rattus norvegicus (Norway rat) | Fmo3 | NP_445885.2 |
Pan troglodytes (chimpanzee) | FMO3 | NP_001009092.1 |
FMO3 | NP_001028065.1 | |
Bos taurus (cattle) | FMO3 | NP_776482.1 |
Hepatic Flavin-Containing Monooxygenase 3 Enzyme Suppressed by Type 1 Allergy-Produced Nitric Oxide.
Tanino T, Bando T, Komada A, Nojiri Y, Okada Y, Ueda Y, Sakurai E
Drug metabolism and disposition: the biological fate of chemicals45(11)1189-1196(2017 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
FMO3 can contribute to the regulation of glucose metabolism in the liver by reducing lipid-induced endoplasmic reticulum stress and the expression of PEPCK, independently of insulin signal transduction.
Title: Flavin-Containing Monooxygenase 3 Reduces Endoplasmic Reticulum Stress in Lipid-Treated Hepatocytes.
FMO3 is increased in obese/insulin resistant male mice and necessary for expression of FoxO1.
Title: Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis.
a major role for FMO3 in modulating glucose and lipid homeostasis
Title: Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis.
Report temporal changes in hepatic Fmo3 gene expression under different conditions all known to cause hepatic oxidative stress.
Title: Differential Fmo3 gene expression in various liver injury models involving hepatic oxidative stress in mice.
Fmo3 expression and function plays a role in protecting the liver from acetaminophen-induced toxicity.
Title: Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes.
The following Fmo3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fmo3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu01248 | |
Clone ID Related Accession (Same CDS sequence) | NM_008030.2 | |
Accession Version | NM_008030.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1605bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-01 | |
Organism | Mus musculus(house mouse) | |
Product | dimethylaniline monooxygenase [N-oxide-forming] 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK050123.1, AK149440.1 and D18023.1. On Aug 25, 2015 this sequence version replaced NM_008030.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK149440.1, U87147.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849386 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAAGAAGA AAGTGGCCAT CATTGGAGCT GGTGTCAGTG GCCTGGCTGC CATCAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_032056.1 |
CDS | 65..1669 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGAAGAAGA AAGTGGCCAT CATTGGAGCT GGTGTCAGTG GCCTGGCTGC CATCAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Hepatic Flavin-Containing Monooxygenase 3 Enzyme Suppressed by Type 1 Allergy-Produced Nitric Oxide. |