Gene Symbol | Fzd8 |
Entrez Gene ID | 14370 |
Full Name | frizzled class receptor 8 |
Synonyms | Fz8 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Fzd8 cDNA ORF clone
Gene Symbol | Fzd8 |
Entrez Gene ID | 14370 |
Full Name | frizzled class receptor 8 |
Synonyms | Fz8 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_008058.2 | NP_032084.2 | frizzled-8 precursor |
Homo sapiens (human) | FZD8 | NP_114072.1 |
Mus musculus (house mouse) | Fzd8 | NP_032084.2 |
Rattus norvegicus (Norway rat) | Fzd8 | NP_001037716.1 |
Rattus norvegicus (Norway rat) | LOC100909849 | XP_003751769.1 |
Xenopus tropicalis (tropical clawed frog) | fzd8 | NP_001090860.2 |
Canis lupus familiaris (dog) | FZD8 | XP_005617125.1 |
Caenorhabditis elegans (roundworm) | cfz-2 | NP_503965.2 |
Pan troglodytes (chimpanzee) | FZD8 | XP_001142144.2 |
Danio rerio (zebrafish) | fzd8a | NP_570993.2 |
FZD8 | XP_001096837.1 | |
Bos taurus (cattle) | FZD8 | XP_005214377.1 |
Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.
Sigal M, Logan CY, Kapalczynska M, Mollenkopf HJ, Berger H, Wiedenmann B, Nusse R, Amieva MR, Meyer TF
Nature548(7668)451-455(2017 08)
Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.
Sandberg M, Flandin P, Silberberg S, Su-Feher L, Price JD, Hu JS, Kim C, Visel A, Nord AS, Rubenstein JLR
Neuron91(6)1260-1275(2016 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Increasing amounts of soluble Frizzled8-cysteine-rich-domain protein modulated Wnt3a signaling in a biphasic manner.
Title: Molecular dissection of Wnt3a-Frizzled8 interaction reveals essential and modulatory determinants of Wnt signaling activity.
Fzd8 and beta-catenin negatively regulate osteoclast differentiation independent of osteoblasts.
Title: Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerin.
Study shows Flamingo (Fmi) and Frizzled (Fz) 8, members of noncanonical Wnt signaling, both express in and functionally maintain quiescent long-term hematopoietic stem cells.
Title: Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche.
study presents the structure of Xenopus Wnt8 (XWnt8) in complex with the mouse Fz8-cysteine-rich domain to a resolution of 3.25 A
Title: Structural basis of Wnt recognition by Frizzled.
studies suggest a dose-dependent regulation of signaling by Fz5 and Fz8 in optic fissure/disc formation and progenitor expansion
Title: Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma.
The following Fzd8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fzd8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu22805 | |
Clone ID Related Accession (Same CDS sequence) | NM_008058.2 | |
Accession Version | NM_008058.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2058bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | frizzled-8 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC132543.1 and AC108777.7. On Jun 30, 2009 this sequence version replaced NM_008058.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end. |
1 | ATGGAGTGGG GTTACCTGTT GGAAGTGACC TCGCTCCTAG CCGCCTTGGC GGTGCTACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_032084.2 |
CDS | 65..2122 |
Translation |
Target ORF information:
Target ORF information:
|
NM_008058.2 |
1 | ATGGAGTGGG GTTACCTGTT GGAAGTGACC TCGCTCCTAG CCGCCTTGGC GGTGCTACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis. |
Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons. |