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Lilr4b cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Lilr4b
Entrez Gene ID 14727
Full Name leukocyte immunoglobulin-like receptor, subfamily B, member 4B
Synonyms Gp49a,gp49
General protein information
Preferred Names

leukocyte immunoglobulin-like receptor, subfamily B, member 4B

Names

mast cell surface glycoprotein Gp49A
glycoprotein 49 A
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

10

10|10 B3

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_008147.2 NP_032173.1 mast cell surface glycoprotein Gp49A isoform 1 precursor
NM_001291892.1 NP_001278821.1 mast cell surface glycoprotein Gp49A isoform 2
NM_001291893.1 NP_001278822.1 mast cell surface glycoprotein Gp49A isoform 3 precursor

Pathways from BioSystems


Homologies


LILRB4 NP_001035766.1
Mus musculus (house mouse) Lilrb4 NP_038560.1
Homo sapiens (human) LILRB4 NP_001265355.1
Pan troglodytes (chimpanzee) LILRB4 NP_001009045.1
Mus musculus (house mouse) Gp49a NP_032173.1
Rattus norvegicus (Norway rat) Lilrb4 NP_001013916.1

Gene Ontology


Bibliography

Related articles in PubMed

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice.
Sferruzzi-Perri AN, Macpherson AM, Roberts CT, Robertson SA
Biology of reproduction81(1)207-21(2009 Jul)

The gp49A gene has extensive sequence conservation with the gp49B gene and provides gp49A protein, a unique member of a large family of activating and inhibitory receptors of the immunoglobulin superfamily.
McCormick MJ, Castells MC, Austen KF, Katz HR
Immunogenetics50(5-6)286-94(1999 Dec)

Association of tyrosine phosphatases SHP-1 and SHP-2, inositol 5-phosphatase SHIP with gp49B1, and chromosomal assignment of the gene.
Kuroiwa A, Yamashita Y, Inui M, Yuasa T, Ono M, Nagabukuro A, Matsuda Y, Takai T
The Journal of biological chemistry273(2)1070-4(1998 Jan)

Cloning of the gp49B gene of the immunoglobulin superfamily and demonstration that one of its two products is an early-expressed mast cell surface protein originally described as gp49.
Castells MC, Wu X, Arm JP, Austen KF, Katz HR
The Journal of biological chemistry269(11)8393-401(1994 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lilr4b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lilr4b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu19933 NM_001291893.1
Latest version!		 Mus musculus leukocyte immunoglobulin-like receptor, subfamily B, member 4B (Lilr4b), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
OMu19939 NM_001291892.1
Latest version!		 Mus musculus leukocyte immunoglobulin-like receptor, subfamily B, member 4B (Lilr4b), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
OMu19958 NM_008147.2
Latest version!		 Mus musculus leukocyte immunoglobulin-like receptor, subfamily B, member 4B (Lilr4b), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu19933
Clone ID Related Accession (Same CDS sequence) NM_001291893.1
Accession Version NM_001291893.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 627bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-10-24
Organism Mus musculus(house mouse)
Product mast cell surface glycoprotein Gp49A isoform 3 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY198371.1, BC065784.1 and BY543077.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC065784.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
ATGATCGCCA TGCTCACAGT GCTGCTATAC CTTGCTCTTA TTCTGGAACC CAGGACTGCA 
GTACAGGCAG GAGCATATGA AAATCCCAGC CTGTCAGTCT ATCCCAGCTC TAATGTGACC 
TCTGGAGTTT CCATATCCTT TAAGTGCAGC TCATCCACAC TATTTGGCAG ATTCATTCTG 
ATACAGGAAG GAAAGCATGG CCTCTCGTGG ACCCTGGACT CACAGCATCA GGCCAATCAG 
CCAACCCATG CTACTTTTGT TCTGGATGCT GTTGCTCCCA ACCACAATGG AACATTCAGA 
TGCTATGGCT TCTTTAGAAA TGAACCACAG GTGTGGTCAA AACCAAGTAA CTCCCTAGAC 
CTCATGATCT CAGAAACCAA GGAACAGTCC TGTACACCCA CTGAAGATGG ACTGGAAACA 
TACCAGAAGA TTTTGATTGG AGTCCTGGTG TCATTCCTCC TGCTTTTCTT CCTCCTGCTT 
TTTCTCATCC TCATCGGATA CCAGTGTCGT CACAAAAATA AGGCTAATGC TTCTGTGAAG 
AACACACAAT CTGAGGACAA TGCAGAGCTG AACAGTTGGA ACCCACAAAA TGAAGACCCC 
CCCAGGGAAT TGTGTACGCC CAGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278822.1
CDS109..735
Translation

Target ORF information:

RefSeq Version NM_001291893.1
Organism Mus musculus(house mouse)
Definition Mus musculus leukocyte immunoglobulin-like receptor, subfamily B, member 4B (Lilr4b), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001291893.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGATCGCCA TGCTCACAGT GCTGCTATAC CTTGCTCTTA TTCTGGAACC CAGGACTGCA 
GTACAGGCAG GAGCATATGA AAATCCCAGC CTGTCAGTCT ATCCCAGCTC TAATGTGACC 
TCTGGAGTTT CCATATCCTT TAAGTGCAGC TCATCCACAC TATTTGGCAG ATTCATTCTG 
ATACAGGAAG GAAAGCATGG CCTCTCGTGG ACCCTGGACT CACAGCATCA GGCCAATCAG 
CCAACCCATG CTACTTTTGT TCTGGATGCT GTTGCTCCCA ACCACAATGG AACATTCAGA 
TGCTATGGCT TCTTTAGAAA TGAACCACAG GTGTGGTCAA AACCAAGTAA CTCCCTAGAC 
CTCATGATCT CAGAAACCAA GGAACAGTCC TGTACACCCA CTGAAGATGG ACTGGAAACA 
TACCAGAAGA TTTTGATTGG AGTCCTGGTG TCATTCCTCC TGCTTTTCTT CCTCCTGCTT 
TTTCTCATCC TCATCGGATA CCAGTGTCGT CACAAAAATA AGGCTAATGC TTCTGTGAAG 
AACACACAAT CTGAGGACAA TGCAGAGCTG AACAGTTGGA ACCCACAAAA TGAAGACCCC 
CCCAGGGAAT TGTGTACGCC CAGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu19939
Clone ID Related Accession (Same CDS sequence) NM_001291892.1
Accession Version NM_001291892.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 651bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-10-21
Organism Mus musculus(house mouse)
Product mast cell surface glycoprotein Gp49A isoform 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY198371.1, AK171573.1, AC153530.9, BC065784.1 and BY543077.1. Transcript Variant: This variant (2) uses an alternate splice junction at the 3' end of the first exon and initiates translation at an alternate start codon compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK167751.1, AK171573.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
ATGACAGCCT CATATGCAGG CATATATAAC TGTTACTATA AGAGTGCTGC TGGCTTCTCA 
GAGCACAGTG ATGCCATGGA GCTGGTGATG ACAGGAGCAT ATGAAAATCC CAGCCTGTCA 
GTCTATCCCA GCTCTAATGT GACCTCTGGA GTTTCCATAT CCTTTAAGTG CAGCTCATCC 
ACACTATTTG GCAGATTCAT TCTGATACAG GAAGGAAAGC ATGGCCTCTC GTGGACCCTG 
GACTCACAGC ATCAGGCCAA TCAGCCAACC CATGCTACTT TTGTTCTGGA TGCTGTTGCT 
CCCAACCACA ATGGAACATT CAGATGCTAT GGCTTCTTTA GAAATGAACC ACAGGTGTGG 
TCAAAACCAA GTAACTCCCT AGACCTCATG ATCTCAGAAA CCAAGGAACA GTCCTGTACA 
CCCACTGAAG ATGGACTGGA AACATACCAG AAGATTTTGA TTGGAGTCCT GGTGTCATTC 
CTCCTGCTTT TCTTCCTCCT GCTTTTTCTC ATCCTCATCG GATACCAGTG TCGTCACAAA 
AATAAGGCTA ATGCTTCTGT GAAGAACACA CAATCTGAGG ACAATGCAGA GCTGAACAGT 
TGGAACCCAC AAAATGAAGA CCCCCCCAGG GAATTGTGTA CGCCCAGGTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278821.1
CDS375..1025
Translation

Target ORF information:

RefSeq Version NM_001291892.1
Organism Mus musculus(house mouse)
Definition Mus musculus leukocyte immunoglobulin-like receptor, subfamily B, member 4B (Lilr4b), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001291892.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGACAGCCT CATATGCAGG CATATATAAC TGTTACTATA AGAGTGCTGC TGGCTTCTCA 
GAGCACAGTG ATGCCATGGA GCTGGTGATG ACAGGAGCAT ATGAAAATCC CAGCCTGTCA 
GTCTATCCCA GCTCTAATGT GACCTCTGGA GTTTCCATAT CCTTTAAGTG CAGCTCATCC 
ACACTATTTG GCAGATTCAT TCTGATACAG GAAGGAAAGC ATGGCCTCTC GTGGACCCTG 
GACTCACAGC ATCAGGCCAA TCAGCCAACC CATGCTACTT TTGTTCTGGA TGCTGTTGCT 
CCCAACCACA ATGGAACATT CAGATGCTAT GGCTTCTTTA GAAATGAACC ACAGGTGTGG 
TCAAAACCAA GTAACTCCCT AGACCTCATG ATCTCAGAAA CCAAGGAACA GTCCTGTACA 
CCCACTGAAG ATGGACTGGA AACATACCAG AAGATTTTGA TTGGAGTCCT GGTGTCATTC 
CTCCTGCTTT TCTTCCTCCT GCTTTTTCTC ATCCTCATCG GATACCAGTG TCGTCACAAA 
AATAAGGCTA ATGCTTCTGT GAAGAACACA CAATCTGAGG ACAATGCAGA GCTGAACAGT 
TGGAACCCAC AAAATGAAGA CCCCCCCAGG GAATTGTGTA CGCCCAGGTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu19958
Clone ID Related Accession (Same CDS sequence) NM_008147.2
Accession Version NM_008147.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 912bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-27
Organism Mus musculus(house mouse)
Product mast cell surface glycoprotein Gp49A isoform 1 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY198371.1, BY204344.1, AC153530.9, BC065784.1 and BY543077.1. On May 7, 2014 this sequence version replaced NM_008147.1. Transcript Variant: This variant (1) encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: M65027.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGATCGCCA TGCTCACAGT GCTGCTATAC CTTGCTCTTA TTCTGGAACC CAGGACTGCA 
GTACAGGCAG GACACCTCCC AAAACCCATC ATCTGGGCTG AGCCAGGCTC TGTGATCGCT 
GCGTATACAT CTGTGATTAT CTGGTGTTGG GGTTCCTGGG AGGCCCAGTA TTATTATCTG 
GATAAAGAGA AAAGTGTAAA TCCTTGGGAC ACTGAAGTCC CTCTGGAAAA CAGGAATAAG 
ACCAAGTTCA AAATTCGATT TATGACAGCC TCATATGCAG GCATATATAA CTGTTACTAT 
AAGAGTGCTG CTGGCTTCTC AGAGCACAGT GATGCCATGG AGCTGGTGAT GACAGGAGCA 
TATGAAAATC CCAGCCTGTC AGTCTATCCC AGCTCTAATG TGACCTCTGG AGTTTCCATA 
TCCTTTAAGT GCAGCTCATC CACACTATTT GGCAGATTCA TTCTGATACA GGAAGGAAAG 
CATGGCCTCT CGTGGACCCT GGACTCACAG CATCAGGCCA ATCAGCCAAC CCATGCTACT 
TTTGTTCTGG ATGCTGTTGC TCCCAACCAC AATGGAACAT TCAGATGCTA TGGCTTCTTT 
AGAAATGAAC CACAGGTGTG GTCAAAACCA AGTAACTCCC TAGACCTCAT GATCTCAGAA 
ACCAAGGAAC AGTCCTGTAC ACCCACTGAA GATGGACTGG AAACATACCA GAAGATTTTG 
ATTGGAGTCC TGGTGTCATT CCTCCTGCTT TTCTTCCTCC TGCTTTTTCT CATCCTCATC 
GGATACCAGT GTCGTCACAA AAATAAGGCT AATGCTTCTG TGAAGAACAC ACAATCTGAG 
GACAATGCAG AGCTGAACAG TTGGAACCCA CAAAATGAAG ACCCCCCCAG GGAATTGTGT 
ACGCCCAGGT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_032173.1
CDS109..1020
Translation

Target ORF information:

RefSeq Version NM_008147.2
Organism Mus musculus(house mouse)
Definition Mus musculus leukocyte immunoglobulin-like receptor, subfamily B, member 4B (Lilr4b), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_008147.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGATCGCCA TGCTCACAGT GCTGCTATAC CTTGCTCTTA TTCTGGAACC CAGGACTGCA 
GTACAGGCAG GACACCTCCC AAAACCCATC ATCTGGGCTG AGCCAGGCTC TGTGATCGCT 
GCGTATACAT CTGTGATTAT CTGGTGTTGG GGTTCCTGGG AGGCCCAGTA TTATTATCTG 
GATAAAGAGA AAAGTGTAAA TCCTTGGGAC ACTGAAGTCC CTCTGGAAAA CAGGAATAAG 
ACCAAGTTCA AAATTCGATT TATGACAGCC TCATATGCAG GCATATATAA CTGTTACTAT 
AAGAGTGCTG CTGGCTTCTC AGAGCACAGT GATGCCATGG AGCTGGTGAT GACAGGAGCA 
TATGAAAATC CCAGCCTGTC AGTCTATCCC AGCTCTAATG TGACCTCTGG AGTTTCCATA 
TCCTTTAAGT GCAGCTCATC CACACTATTT GGCAGATTCA TTCTGATACA GGAAGGAAAG 
CATGGCCTCT CGTGGACCCT GGACTCACAG CATCAGGCCA ATCAGCCAAC CCATGCTACT 
TTTGTTCTGG ATGCTGTTGC TCCCAACCAC AATGGAACAT TCAGATGCTA TGGCTTCTTT 
AGAAATGAAC CACAGGTGTG GTCAAAACCA AGTAACTCCC TAGACCTCAT GATCTCAGAA 
ACCAAGGAAC AGTCCTGTAC ACCCACTGAA GATGGACTGG AAACATACCA GAAGATTTTG 
ATTGGAGTCC TGGTGTCATT CCTCCTGCTT TTCTTCCTCC TGCTTTTTCT CATCCTCATC 
GGATACCAGT GTCGTCACAA AAATAAGGCT AATGCTTCTG TGAAGAACAC ACAATCTGAG 
GACAATGCAG AGCTGAACAG TTGGAACCCA CAAAATGAAG ACCCCCCCAG GGAATTGTGT 
ACGCCCAGGT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W


book

Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice.
Biology of reproduction81(1)207-21(2009 Jul)
Sferruzzi-Perri AN,Macpherson AM,Roberts CT,Robertson SA


book

The gp49A gene has extensive sequence conservation with the gp49B gene and provides gp49A protein, a unique member of a large family of activating and inhibitory receptors of the immunoglobulin superfamily.
Immunogenetics50(5-6)286-94(1999 Dec)
McCormick MJ,Castells MC,Austen KF,Katz HR


book

Association of tyrosine phosphatases SHP-1 and SHP-2, inositol 5-phosphatase SHIP with gp49B1, and chromosomal assignment of the gene.
The Journal of biological chemistry273(2)1070-4(1998 Jan)
Kuroiwa A,Yamashita Y,Inui M,Yuasa T,Ono M,Nagabukuro A,Matsuda Y,Takai T


book

Cloning of the gp49B gene of the immunoglobulin superfamily and demonstration that one of its two products is an early-expressed mast cell surface protein originally described as gp49.
The Journal of biological chemistry269(11)8393-401(1994 Mar)
Castells MC,Wu X,Arm JP,Austen KF,Katz HR