Gene Symbol | Gpc4 |
Entrez Gene ID | 14735 |
Full Name | glypican 4 |
Synonyms | 9530073D23Rik,AF311610,AI385680,AI661372,K-glypican |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Gpc4 cDNA ORF clone
gRNAs
Gene Symbol | Gpc4 |
Entrez Gene ID | 14735 |
Full Name | glypican 4 |
Synonyms | 9530073D23Rik,AF311610,AI385680,AI661372,K-glypican |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_011250978.2 | XP_011249280.1 | glypican-4 isoform X1 |
NM_008150.2 | NP_032176.2 | glypican-4 precursor |
XM_011250978.3 | XP_011249280.1 | glypican-4 isoform X1 |
Rattus norvegicus (Norway rat) | Gpc4 | NP_001014130.1 |
Bos taurus (cattle) | GPC4 | NP_001192713.1 |
Mus musculus (house mouse) | Gpc4 | NP_032176.2 |
Gallus gallus (chicken) | GPC4 | XP_420222.3 |
Danio rerio (zebrafish) | gpc4 | NP_571935.2 |
Xenopus tropicalis (tropical clawed frog) | gpc4 | XP_002932634.1 |
Canis lupus familiaris (dog) | GPC4 | XP_549265.2 |
GPC4 | XP_001097252.1 | |
Drosophila melanogaster (fruit fly) | dlp | NP_996075.2 |
Caenorhabditis elegans (roundworm) | gpn-1 | NP_510582.1 |
Homo sapiens (human) | GPC4 | NP_001439.2 |
Pan troglodytes (chimpanzee) | GPC4 | XP_529161.3 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003559 | XP_313306.5 |
Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation.
Farhy-Tselnicker I, van Casteren ACM, Lee A, Chang VT, Aricescu AR, Allen NJ
Neuron96(2)428-445.e13(2017 Oct)
Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Naba A, Clauser KR, Mani DR, Carr SA, Hynes RO
Scientific reports740495(2017 Jan)
Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones.
Dierker T, Bachvarova V, Krause Y, Li JP, Kjell?n L, Seidler DG, Vortkamp A
Matrix biology : journal of the International Society for Matrix Biology4982-92(2016 Jan)
Systems genetic analysis of hippocampal neuroanatomy and spatial learning in mice.
Delprato A, Bonheur B, Alg?o MP, Rosay P, Lu L, Williams RW, Crusio WE
Genes, brain, and behavior14(8)591-606(2015 11)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Glypican 4 induces release of neuronal pentraxin 1 from presynaptic terminals.
Title: Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation.
Findings establish that Gpc4 acts at the interface of extrinsic and intrinsic signal regulation to fine tune stem cell fate.
Title: Modulating Glypican4 suppresses tumorigenicity of embryonic stem cells while preserving self-renewal and pluripotency.
data identify glypicans as a family of novel astrocyte-derived molecules that are necessary and sufficient to promote glutamate receptor clustering and receptivity and to induce the formation of postsynaptically functioning CNS synapses
Title: Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors.
complex pattern of glypican-4 mRNA localization at embryonic days 7-10.5, including sites in the anterior forebrain neuroepithelium, branchial arches, optic and otic vesicles, limb buds and somites
Title: Expression pattern of glypican-4 suggests multiple roles during mouse development.
The following Gpc4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gpc4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu21813 | |
Clone ID Related Accession (Same CDS sequence) | NM_008150.2 | |
Accession Version | NM_008150.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1674bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-06 | |
Organism | Mus musculus(house mouse) | |
Product | glypican-4 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL672019.7, CJ187434.1, BQ559580.1, CN710713.1, CF168390.1, AI892739.1 and BX088698.22. On May 29, 2009 this sequence version replaced NM_008150.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC006622.1, X83577.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164137 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCACGCT TAGGCTTGCT CGCGCTCCTC TGCACCCTGG CCGCGCTCAG CGCCTCGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_032176.2 |
CDS | 149..1822 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGCACGCT TAGGCTTGCT CGCGCTCCTC TGCACCCTGG CCGCGCTCAG CGCCTCGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67841 | |
Clone ID Related Accession (Same CDS sequence) | XM_011250978.2 , XM_011250978.3 | |
Accession Version | XM_011250978.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | glypican-4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011250978.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATCATT TAAAAGGTGA CCATTTGAAG ATCTGTCCCC AGGATTATAC ATGCTGTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011249280.1 |
CDS | 333..1862 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAATCATT TAAAAGGTGA CCATTTGAAG ATCTGTCCCC AGGATTATAC ATGCTGTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67841 | |
Clone ID Related Accession (Same CDS sequence) | XM_011250978.2 , XM_011250978.3 | |
Accession Version | XM_011250978.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | glypican-4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011250978.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATCATT TAAAAGGTGA CCATTTGAAG ATCTGTCCCC AGGATTATAC ATGCTGTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011249280.1 |
CDS | 1503..3032 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAATCATT TAAAAGGTGA CCATTTGAAG ATCTGTCCCC AGGATTATAC ATGCTGTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation. |
Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. |
Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones. |
Systems genetic analysis of hippocampal neuroanatomy and spatial learning in mice. |