Gene Symbol | Hgs |
Entrez Gene ID | 15239 |
Full Name | HGF-regulated tyrosine kinase substrate |
Synonyms | Hgr,Hrs,ZFYVE8,tn |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Hgs cDNA ORF clone
gRNAs
Gene Symbol | Hgs |
Entrez Gene ID | 15239 |
Full Name | HGF-regulated tyrosine kinase substrate |
Synonyms | Hgr,Hrs,ZFYVE8,tn |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006532270.2 | XP_006532333.2 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 |
XM_006532274.2 | XP_006532337.2 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X5 |
XM_006532272.3 | XP_006532335.2 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X3 |
XM_006532273.3 | XP_006532336.2 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X4 |
XM_030245591.1 | XP_030101451.1 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X8 |
NM_008244.3 | NP_032270.3 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform 2 |
XM_006532270.3 | XP_006532333.2 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 |
XM_030245590.1 | XP_030101450.1 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X7 |
XM_006532272.2 | XP_006532335.2 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X3 |
XM_017314293.1 | XP_017169782.1 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X6 |
XM_017314293.2 | XP_017169782.1 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X6 |
NM_001159328.1 | NP_001152800.1 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform 1 |
XM_006532271.3 | XP_006532334.2 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X2 |
XM_006532271.2 | XP_006532334.2 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X2 |
XM_006532273.2 | XP_006532336.2 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X4 |
XM_006532274.3 | XP_006532337.2 | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X5 |
HGS | XP_001111673.1 | |
Bos taurus (cattle) | HGS | NP_001039554.1 |
Danio rerio (zebrafish) | hgs | NP_956162.1 |
Caenorhabditis elegans (roundworm) | hgrs-1 | NP_501375.2 |
Canis lupus familiaris (dog) | HGS | XP_005624060.1 |
Mus musculus (house mouse) | Hgs | NP_001152800.1 |
Gallus gallus (chicken) | HGS | XP_426233.3 |
Drosophila melanogaster (fruit fly) | Hrs | NP_525099.3 |
Pan troglodytes (chimpanzee) | HGS | XP_511742.4 |
Rattus norvegicus (Norway rat) | Hgs | NP_062260.2 |
Xenopus tropicalis (tropical clawed frog) | hgs | NP_001016513.1 |
Homo sapiens (human) | HGS | NP_004703.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008887 | XP_319634.4 |
ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways.
Oshima R, Hasegawa T, Tamai K, Sugeno N, Yoshida S, Kobayashi J, Kikuchi A, Baba T, Futatsugi A, Sato I, Satoh K, Takeda A, Aoki M, Tanaka N
Scientific reports624997(2016 04)
Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS.
Watson JA, Bhattacharyya BJ, Vaden JH, Wilson JA, Icyuz M, Howard AD, Phillips E, DeSilva TM, Siegal GP, Bean AJ, King GD, Phillips SE, Miller RJ, Wilson SM
PLoS genetics11(6)e1005290(2015 Jun)
Smooth Muscle Hgs Deficiency Leads to Impaired Esophageal Motility.
Chen J, Hou N, Zhang C, Teng Y, Cheng X, Li Z, Ren J, Zeng J, Li R, Wang W, Yang X, Lan Y
International journal of biological sciences11(7)794-802(2015)
ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation.
Kojima K, Amano Y, Yoshino K, Tanaka N, Sugamura K, Takeshita T
The Journal of biological chemistry289(48)33296-310(2014 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
HGS expression in the nervous system is developmentally regulated.HGS is required for motor neuron function.
Title: Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS.
Smooth Muscle Hgs Deficiency Leads to Impaired Esophageal Motility.
Title: Smooth Muscle Hgs Deficiency Leads to Impaired Esophageal Motility.
ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation.
Title: ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation.
These results indicate that Hrs plays important roles during peripheral development and physiological functions of B lymphocytes.
Title: Hepatocyte growth factor regulated tyrosine kinase substrate in the peripheral development and function of B-cells.
A new mechanism to modify BMP signaling by Hgs during early mouse development.
Title: Hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs) is involved in BMP signaling through phosphorylation of SMADS and TAK1 in early mouse embryo.
The following Hgs gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hgs cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu15386 | |
Clone ID Related Accession (Same CDS sequence) | NM_008244.3 | |
Accession Version | NM_008244.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2328bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY315543.1, AK046299.1, AK145031.1 and CJ294093.1. On Apr 16, 2009 this sequence version replaced NM_008244.2. Transcript Variant: This variant (2) uses an alternate in-frame splice site, compared to variant 1. This difference results in a protein (isoform 2) that is one amino acid shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC003239.1, AK046299.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_032270.3 |
CDS | 93..2420 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15419 | |
Clone ID Related Accession (Same CDS sequence) | NM_001159328.1 | |
Accession Version | NM_001159328.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2331bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY315543.1, AK046299.1, AK145031.1 and CJ294093.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660821.71039.1, AK145031.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001152800.1 |
CDS | 93..2423 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67943 | |
Clone ID Related Accession (Same CDS sequence) | XM_006532270.2 , XM_006532270.3 | |
Accession Version | XM_006532270.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2418bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006532270.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006532333.2 |
CDS | 88..2505 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67944 | |
Clone ID Related Accession (Same CDS sequence) | XM_006532271.3 , XM_006532271.2 | |
Accession Version | XM_006532271.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2415bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006532271.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006532334.2 |
CDS | 88..2502 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67945 | |
Clone ID Related Accession (Same CDS sequence) | XM_006532272.3 , XM_006532272.2 | |
Accession Version | XM_006532272.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2397bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006532272.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006532335.2 |
CDS | 88..2484 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67946 | |
Clone ID Related Accession (Same CDS sequence) | XM_006532273.3 , XM_006532273.2 | |
Accession Version | XM_006532273.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2394bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006532273.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006532336.2 |
CDS | 88..2481 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67947 | |
Clone ID Related Accession (Same CDS sequence) | XM_006532274.2 , XM_006532274.3 | |
Accession Version | XM_006532274.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2352bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006532274.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006532337.2 |
CDS | 88..2439 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67943 | |
Clone ID Related Accession (Same CDS sequence) | XM_006532270.2 , XM_006532270.3 | |
Accession Version | XM_006532270.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2418bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006532270.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006532333.2 |
CDS | 123..2540 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67944 | |
Clone ID Related Accession (Same CDS sequence) | XM_006532271.3 , XM_006532271.2 | |
Accession Version | XM_006532271.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2415bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006532271.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006532334.2 |
CDS | 123..2537 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67945 | |
Clone ID Related Accession (Same CDS sequence) | XM_006532272.3 , XM_006532272.2 | |
Accession Version | XM_006532272.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2397bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006532272.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006532335.2 |
CDS | 123..2519 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67946 | |
Clone ID Related Accession (Same CDS sequence) | XM_006532273.3 , XM_006532273.2 | |
Accession Version | XM_006532273.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2394bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006532273.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006532336.2 |
CDS | 123..2516 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu67947 | |
Clone ID Related Accession (Same CDS sequence) | XM_006532274.2 , XM_006532274.3 | |
Accession Version | XM_006532274.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2352bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006532274.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006532337.2 |
CDS | 123..2474 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu77747 | |
Clone ID Related Accession (Same CDS sequence) | XM_017314293.1 , XM_017314293.2 | |
Accession Version | XM_017314293.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2349bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X6 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017169782.1 |
CDS | 88..2436 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu77747 | |
Clone ID Related Accession (Same CDS sequence) | XM_017314293.1 , XM_017314293.2 | |
Accession Version | XM_017314293.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2349bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X6 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017314293.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017169782.1 |
CDS | 123..2471 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AAGCCACCAG CCAGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85635 | |
Clone ID Related Accession (Same CDS sequence) | XM_030245590.1 | |
Accession Version | XM_030245590.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2424bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X7 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTTACCT TAGTCTCATA TCCTGGGAGG TTCAGCACGT CAGACAAAGC CACCAGCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030101450.1 |
CDS | 586..3009 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTTTACCT TAGTCTCATA TCCTGGGAGG TTCAGCACGT CAGACAAAGC CACCAGCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85636 | |
Clone ID Related Accession (Same CDS sequence) | XM_030245591.1 | |
Accession Version | XM_030245591.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2334bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | hepatocyte growth factor-regulated tyrosine kinase substrate isoform X8 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTTACCT TAGTCTCATA TCCTGGGAGG TTCAGCACGT CAGACAAAGC CACCAGCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030101451.1 |
CDS | 586..2919 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTTTACCT TAGTCTCATA TCCTGGGAGG TTCAGCACGT CAGACAAAGC CACCAGCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways. |
Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS. |
Smooth Muscle Hgs Deficiency Leads to Impaired Esophageal Motility. |
ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation. |