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Htr6 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Htr6
Entrez Gene ID 15565
Full Name 5-hydroxytryptamine (serotonin) receptor 6
Synonyms 5-HT6
General protein information
Preferred Names

5-hydroxytryptamine (serotonin) receptor 6

Names

5-hydroxytryptamine receptor 6
5-HT-6
serotonin receptor 6
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

4

4 D3|4 70.57 cM

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_011250196.1 XP_011248498.1 5-hydroxytryptamine receptor 6 isoform X1
NM_001377096.1 NP_001364025.1 5-hydroxytryptamine receptor 6
XM_011250196.2 XP_011248498.1 5-hydroxytryptamine receptor 6 isoform X1
NM_021358.2 NP_067333.1 5-hydroxytryptamine receptor 6

Pathways from BioSystems


Homologies


Mus musculus (house mouse) Htr6 NP_067333.1
Rattus norvegicus (Norway rat) Htr6 NP_077341.1
Danio rerio (zebrafish) LOC568269 XP_696681.5
Bos taurus (cattle) HTR6 NP_001192646.1
Homo sapiens (human) HTR6 NP_000862.1
Pan troglodytes (chimpanzee) HTR6 NP_001029264.1
LOC716776 XP_001107724.2
Gallus gallus (chicken) HTR6 NP_001166911.1
Xenopus tropicalis (tropical clawed frog) htr6 XP_002942005.2
Canis lupus familiaris (dog) HTR6 XP_544528.4

Gene Ontology


Bibliography

Related articles in PubMed

Serotonin 5-HT6 receptors affect cognition in a mouse model of Alzheimer's disease by regulating cilia function.
Hu L, Wang B, Zhang Y
Alzheimer's research & therapy9(1)76(2017 Sep)

5-HT
Brodsky M, Lesiak AJ, Croicu A, Cohenca N, Sullivan JM, Neumaier JF
Brain research166010-19(2017 04)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results implicate a role of 5-HT6 receptor signaling in primary cilia morphology, suggest that 5-HT6 receptor research should consider relative levels of receptor expression when evaluating their impact on primary cilia function.
Title: 5-HT

5-HT6/7 receptor antagonist ADN-1184 displays anxiolytic-like activity in animal models of anxiety which employed punished stimuli.
Title: ADN-1184, a monoaminergic ligand with 5-HT6/7 receptor antagonist action, exhibits activity in animal models of anxiety.

SNX14 is a dual endogenous negative regulator in 5-HT6R-mediated signaling pathway.
Title: SNX14 is a bifunctional negative regulator for neuronal 5-HT6 receptor signaling.

Constitutive expression of 5-HT6R controls pyramidal neuron migration through an agonist-independent mechanism that requires Cdk5 activity.
Title: The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism.

Knockdown of MAO-A expression in embryos induces high serotonin levels and abnormal brain development, which can be rescued by inactivation of serotonin receptor-6.
Title: Serotonin receptor 6 mediates defective brain development in monoamine oxidase A-deficient mouse embryos.

The following Htr6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Htr6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu12234 NM_021358.2
Latest version!		 Mus musculus 5-hydroxytryptamine (serotonin) receptor 6 (Htr6), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $223.30
$319.00
OMu12234 NM_001377096.1
Latest version!		 Mus musculus 5-hydroxytryptamine (serotonin) receptor 6 (Htr6), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $223.30
$319.00
OMu12234 XM_011250196.2
Latest version!		 Mus musculus 5-hydroxytryptamine (serotonin) receptor 6 (Htr6), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $223.30
$319.00
View Old Accession Versions >>
OMu12234 XM_011250196.1 Mus musculus 5-hydroxytryptamine (serotonin) receptor 6 (Htr6), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $223.30
$319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu12234
Clone ID Related Accession (Same CDS sequence) XM_011250196.1 , NM_001377096.1 , XM_011250196.2 , NM_021358.2
Accession Version NM_001377096.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1323bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-12
Organism Mus musculus(house mouse)
Product 5-hydroxytryptamine receptor 6
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL805923.6. On Dec 13, 2019 this sequence version replaced XM_011250196.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7974084.501.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849378, SAMN00849379 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length. 

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ATGGTTCCAG AGCCCGGCCC TGTCAACAGT AGCACCCCAG CCTGGGGCCC CGGGCCACCG 
CCAGCCCCAG GGGGCAGCGG CTGGGTGGCC GCTGCGCTGT GCGTGGTCAT CGTGCTGACG 
GCAGCCGCCA ATTCGCTGCT GATCGCGCTC ATCTGCACGC AGCCCGCGCT GCGCAACACG 
TCTAACTTCT TCCTGGTGTC GCTCTTCACG TCGGACCTGA TGGTGGGATT GGTGGTGATG 
CCCCCAGCCA TGCTGAACGC GCTGTATGGG CGCTGGGTGC TAGCTCGCGG CCTCTGTCTG 
CTTTGGACCG CCTTCGACGT GATGTGCTGC AGCGCCTCCA TTCTCAACCT CTGCCTCATC 
AGCCTGGACC GCTACCTGCT CATCCTCTCG CCGCTGCGCT ACAAGCTGCG CATGACAGCC 
CCGCGTGCCC TGGCGCTCAT CCTGGGTGCC TGGAGCCTCG CCGCGCTGGC CTCCTTCCTG 
CCCCTCTTGC TGGGCTGGCA TGAACTGGGC AAAGCTCGAA CATCTGCCCC GGGCCAGTGC 
CGCCTATTGG CCAGCCTGCC TTATGTCCTC GTGGCGTCCG GCGTCACCTT TTTCCTGCCT 
TCGGGTGCCA TCTGCTTCAC CTACTGCAGG ATCTTGCTGG CTGCCCGCAA GCAGGCGGTG 
CAAGTGGCCT CGCTCACCAC GGGCACGGCT ACGGCTGGCC AGGCCTTGGA AACCTTGCAG 
GTGCCCAGGA CACCACGCCC AGGGATGGAG TCTGCTGACA GTAGGCGTCT GACCACCAAG 
CATAGCAGGA AGGCCTTGAA GGCCAGCCTG ACCCTCGGCA TCCTGCTGAG CATGTTCTTT 
GTCACCTGGC TGCCCTTCTT TGTGGCCAGC ATAGCTCAGG CCGTATGTGA CTGCATCTCT 
CCAGGTCTCT TCGATGTCCT CACATGGCTG GGATACTGTA ATAGCACCAT GAACCCTATC 
ATCTATCCCC TCTTCATGCG GGACTTCAAG AGGGCCCTGG GCAGGTTCGT GCCGTGTGTC 
CACTGTCCCC CGGAGCACCG GGCCAGCCCC GCCTCCCCCT CCATGTGGAC CTCTCACAGT 
GGTGCCAGGC CAGGCCTCAG CCTGCAGCAG GTGCTGCCCC TGCCTCTGCC ACCCAACTCA 
GATTCAGACT CAGCTTCAGG GGGCACCTCG GGCCTGCAGC TCACAGCCCA GCTTTTGCTG 
CCTGGAGAGG CGACCCGGGA CCCCCCGCCA CCCACCAGGG CCCCTACTGT GGTCAACTTC 
TTCGTCACAG ACTCTGTGGA GCCTGAGATA CGGCAGCATC CACTTGGTTC CCCCATGAAC 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001364025.1
CDS707..2029
Translation

Target ORF information:

RefSeq Version NM_001377096.1
Organism Mus musculus(house mouse)
Definition Mus musculus 5-hydroxytryptamine (serotonin) receptor 6 (Htr6), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001377096.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGTTCCAG AGCCCGGCCC TGTCAACAGT AGCACCCCAG CCTGGGGCCC CGGGCCACCG 
CCAGCCCCAG GGGGCAGCGG CTGGGTGGCC GCTGCGCTGT GCGTGGTCAT CGTGCTGACG 
GCAGCCGCCA ATTCGCTGCT GATCGCGCTC ATCTGCACGC AGCCCGCGCT GCGCAACACG 
TCTAACTTCT TCCTGGTGTC GCTCTTCACG TCGGACCTGA TGGTGGGATT GGTGGTGATG 
CCCCCAGCCA TGCTGAACGC GCTGTATGGG CGCTGGGTGC TAGCTCGCGG CCTCTGTCTG 
CTTTGGACCG CCTTCGACGT GATGTGCTGC AGCGCCTCCA TTCTCAACCT CTGCCTCATC 
AGCCTGGACC GCTACCTGCT CATCCTCTCG CCGCTGCGCT ACAAGCTGCG CATGACAGCC 
CCGCGTGCCC TGGCGCTCAT CCTGGGTGCC TGGAGCCTCG CCGCGCTGGC CTCCTTCCTG 
CCCCTCTTGC TGGGCTGGCA TGAACTGGGC AAAGCTCGAA CATCTGCCCC GGGCCAGTGC 
CGCCTATTGG CCAGCCTGCC TTATGTCCTC GTGGCGTCCG GCGTCACCTT TTTCCTGCCT 
TCGGGTGCCA TCTGCTTCAC CTACTGCAGG ATCTTGCTGG CTGCCCGCAA GCAGGCGGTG 
CAAGTGGCCT CGCTCACCAC GGGCACGGCT ACGGCTGGCC AGGCCTTGGA AACCTTGCAG 
GTGCCCAGGA CACCACGCCC AGGGATGGAG TCTGCTGACA GTAGGCGTCT GACCACCAAG 
CATAGCAGGA AGGCCTTGAA GGCCAGCCTG ACCCTCGGCA TCCTGCTGAG CATGTTCTTT 
GTCACCTGGC TGCCCTTCTT TGTGGCCAGC ATAGCTCAGG CCGTATGTGA CTGCATCTCT 
CCAGGTCTCT TCGATGTCCT CACATGGCTG GGATACTGTA ATAGCACCAT GAACCCTATC 
ATCTATCCCC TCTTCATGCG GGACTTCAAG AGGGCCCTGG GCAGGTTCGT GCCGTGTGTC 
CACTGTCCCC CGGAGCACCG GGCCAGCCCC GCCTCCCCCT CCATGTGGAC CTCTCACAGT 
GGTGCCAGGC CAGGCCTCAG CCTGCAGCAG GTGCTGCCCC TGCCTCTGCC ACCCAACTCA 
GATTCAGACT CAGCTTCAGG GGGCACCTCG GGCCTGCAGC TCACAGCCCA GCTTTTGCTG 
CCTGGAGAGG CGACCCGGGA CCCCCCGCCA CCCACCAGGG CCCCTACTGT GGTCAACTTC 
TTCGTCACAG ACTCTGTGGA GCCTGAGATA CGGCAGCATC CACTTGGTTC CCCCATGAAC 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu12234
Clone ID Related Accession (Same CDS sequence) XM_011250196.1 , NM_001377096.1 , XM_011250196.2 , NM_021358.2
Accession Version NM_021358.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1323bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-27
Organism Mus musculus(house mouse)
Product 5-hydroxytryptamine receptor 6
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL805923.6. On Nov 17, 2006 this sequence version replaced NM_021358.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC116653.1, AF134158.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849378, SAMN00849379 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGTTCCAG AGCCCGGCCC TGTCAACAGT AGCACCCCAG CCTGGGGCCC CGGGCCACCG 
CCAGCCCCAG GGGGCAGCGG CTGGGTGGCC GCTGCGCTGT GCGTGGTCAT CGTGCTGACG 
GCAGCCGCCA ATTCGCTGCT GATCGCGCTC ATCTGCACGC AGCCCGCGCT GCGCAACACG 
TCTAACTTCT TCCTGGTGTC GCTCTTCACG TCGGACCTGA TGGTGGGATT GGTGGTGATG 
CCCCCAGCCA TGCTGAACGC GCTGTATGGG CGCTGGGTGC TAGCTCGCGG CCTCTGTCTG 
CTTTGGACCG CCTTCGACGT GATGTGCTGC AGCGCCTCCA TTCTCAACCT CTGCCTCATC 
AGCCTGGACC GCTACCTGCT CATCCTCTCG CCGCTGCGCT ACAAGCTGCG CATGACAGCC 
CCGCGTGCCC TGGCGCTCAT CCTGGGTGCC TGGAGCCTCG CCGCGCTGGC CTCCTTCCTG 
CCCCTCTTGC TGGGCTGGCA TGAACTGGGC AAAGCTCGAA CATCTGCCCC GGGCCAGTGC 
CGCCTATTGG CCAGCCTGCC TTATGTCCTC GTGGCGTCCG GCGTCACCTT TTTCCTGCCT 
TCGGGTGCCA TCTGCTTCAC CTACTGCAGG ATCTTGCTGG CTGCCCGCAA GCAGGCGGTG 
CAAGTGGCCT CGCTCACCAC GGGCACGGCT ACGGCTGGCC AGGCCTTGGA AACCTTGCAG 
GTGCCCAGGA CACCACGCCC AGGGATGGAG TCTGCTGACA GTAGGCGTCT GACCACCAAG 
CATAGCAGGA AGGCCTTGAA GGCCAGCCTG ACCCTCGGCA TCCTGCTGAG CATGTTCTTT 
GTCACCTGGC TGCCCTTCTT TGTGGCCAGC ATAGCTCAGG CCGTATGTGA CTGCATCTCT 
CCAGGTCTCT TCGATGTCCT CACATGGCTG GGATACTGTA ATAGCACCAT GAACCCTATC 
ATCTATCCCC TCTTCATGCG GGACTTCAAG AGGGCCCTGG GCAGGTTCGT GCCGTGTGTC 
CACTGTCCCC CGGAGCACCG GGCCAGCCCC GCCTCCCCCT CCATGTGGAC CTCTCACAGT 
GGTGCCAGGC CAGGCCTCAG CCTGCAGCAG GTGCTGCCCC TGCCTCTGCC ACCCAACTCA 
GATTCAGACT CAGCTTCAGG GGGCACCTCG GGCCTGCAGC TCACAGCCCA GCTTTTGCTG 
CCTGGAGAGG CGACCCGGGA CCCCCCGCCA CCCACCAGGG CCCCTACTGT GGTCAACTTC 
TTCGTCACAG ACTCTGTGGA GCCTGAGATA CGGCAGCATC CACTTGGTTC CCCCATGAAC 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_067333.1
CDS29..1351
Translation

Target ORF information:

RefSeq Version NM_021358.2
Organism Mus musculus(house mouse)
Definition Mus musculus 5-hydroxytryptamine (serotonin) receptor 6 (Htr6), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_021358.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGTTCCAG AGCCCGGCCC TGTCAACAGT AGCACCCCAG CCTGGGGCCC CGGGCCACCG 
CCAGCCCCAG GGGGCAGCGG CTGGGTGGCC GCTGCGCTGT GCGTGGTCAT CGTGCTGACG 
GCAGCCGCCA ATTCGCTGCT GATCGCGCTC ATCTGCACGC AGCCCGCGCT GCGCAACACG 
TCTAACTTCT TCCTGGTGTC GCTCTTCACG TCGGACCTGA TGGTGGGATT GGTGGTGATG 
CCCCCAGCCA TGCTGAACGC GCTGTATGGG CGCTGGGTGC TAGCTCGCGG CCTCTGTCTG 
CTTTGGACCG CCTTCGACGT GATGTGCTGC AGCGCCTCCA TTCTCAACCT CTGCCTCATC 
AGCCTGGACC GCTACCTGCT CATCCTCTCG CCGCTGCGCT ACAAGCTGCG CATGACAGCC 
CCGCGTGCCC TGGCGCTCAT CCTGGGTGCC TGGAGCCTCG CCGCGCTGGC CTCCTTCCTG 
CCCCTCTTGC TGGGCTGGCA TGAACTGGGC AAAGCTCGAA CATCTGCCCC GGGCCAGTGC 
CGCCTATTGG CCAGCCTGCC TTATGTCCTC GTGGCGTCCG GCGTCACCTT TTTCCTGCCT 
TCGGGTGCCA TCTGCTTCAC CTACTGCAGG ATCTTGCTGG CTGCCCGCAA GCAGGCGGTG 
CAAGTGGCCT CGCTCACCAC GGGCACGGCT ACGGCTGGCC AGGCCTTGGA AACCTTGCAG 
GTGCCCAGGA CACCACGCCC AGGGATGGAG TCTGCTGACA GTAGGCGTCT GACCACCAAG 
CATAGCAGGA AGGCCTTGAA GGCCAGCCTG ACCCTCGGCA TCCTGCTGAG CATGTTCTTT 
GTCACCTGGC TGCCCTTCTT TGTGGCCAGC ATAGCTCAGG CCGTATGTGA CTGCATCTCT 
CCAGGTCTCT TCGATGTCCT CACATGGCTG GGATACTGTA ATAGCACCAT GAACCCTATC 
ATCTATCCCC TCTTCATGCG GGACTTCAAG AGGGCCCTGG GCAGGTTCGT GCCGTGTGTC 
CACTGTCCCC CGGAGCACCG GGCCAGCCCC GCCTCCCCCT CCATGTGGAC CTCTCACAGT 
GGTGCCAGGC CAGGCCTCAG CCTGCAGCAG GTGCTGCCCC TGCCTCTGCC ACCCAACTCA 
GATTCAGACT CAGCTTCAGG GGGCACCTCG GGCCTGCAGC TCACAGCCCA GCTTTTGCTG 
CCTGGAGAGG CGACCCGGGA CCCCCCGCCA CCCACCAGGG CCCCTACTGT GGTCAACTTC 
TTCGTCACAG ACTCTGTGGA GCCTGAGATA CGGCAGCATC CACTTGGTTC CCCCATGAAC 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu12234
Clone ID Related Accession (Same CDS sequence) XM_011250196.1 , NM_001377096.1 , XM_011250196.2 , NM_021358.2
Accession Version XM_011250196.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1323bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-02-08
Organism Mus musculus(House mouse)
Product 5-hydroxytryptamine receptor 6 isoform X1
Comment 

1
61
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181
241
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ATGGTTCCAG AGCCCGGCCC TGTCAACAGT AGCACCCCAG CCTGGGGCCC CGGGCCACCG 
CCAGCCCCAG GGGGCAGCGG CTGGGTGGCC GCTGCGCTGT GCGTGGTCAT CGTGCTGACG 
GCAGCCGCCA ATTCGCTGCT GATCGCGCTC ATCTGCACGC AGCCCGCGCT GCGCAACACG 
TCTAACTTCT TCCTGGTGTC GCTCTTCACG TCGGACCTGA TGGTGGGATT GGTGGTGATG 
CCCCCAGCCA TGCTGAACGC GCTGTATGGG CGCTGGGTGC TAGCTCGCGG CCTCTGTCTG 
CTTTGGACCG CCTTCGACGT GATGTGCTGC AGCGCCTCCA TTCTCAACCT CTGCCTCATC 
AGCCTGGACC GCTACCTGCT CATCCTCTCG CCGCTGCGCT ACAAGCTGCG CATGACAGCC 
CCGCGTGCCC TGGCGCTCAT CCTGGGTGCC TGGAGCCTCG CCGCGCTGGC CTCCTTCCTG 
CCCCTCTTGC TGGGCTGGCA TGAACTGGGC AAAGCTCGAA CATCTGCCCC GGGCCAGTGC 
CGCCTATTGG CCAGCCTGCC TTATGTCCTC GTGGCGTCCG GCGTCACCTT TTTCCTGCCT 
TCGGGTGCCA TCTGCTTCAC CTACTGCAGG ATCTTGCTGG CTGCCCGCAA GCAGGCGGTG 
CAAGTGGCCT CGCTCACCAC GGGCACGGCT ACGGCTGGCC AGGCCTTGGA AACCTTGCAG 
GTGCCCAGGA CACCACGCCC AGGGATGGAG TCTGCTGACA GTAGGCGTCT GACCACCAAG 
CATAGCAGGA AGGCCTTGAA GGCCAGCCTG ACCCTCGGCA TCCTGCTGAG CATGTTCTTT 
GTCACCTGGC TGCCCTTCTT TGTGGCCAGC ATAGCTCAGG CCGTATGTGA CTGCATCTCT 
CCAGGTCTCT TCGATGTCCT CACATGGCTG GGATACTGTA ATAGCACCAT GAACCCTATC 
ATCTATCCCC TCTTCATGCG GGACTTCAAG AGGGCCCTGG GCAGGTTCGT GCCGTGTGTC 
CACTGTCCCC CGGAGCACCG GGCCAGCCCC GCCTCCCCCT CCATGTGGAC CTCTCACAGT 
GGTGCCAGGC CAGGCCTCAG CCTGCAGCAG GTGCTGCCCC TGCCTCTGCC ACCCAACTCA 
GATTCAGACT CAGCTTCAGG GGGCACCTCG GGCCTGCAGC TCACAGCCCA GCTTTTGCTG 
CCTGGAGAGG CGACCCGGGA CCCCCCGCCA CCCACCAGGG CCCCTACTGT GGTCAACTTC 
TTCGTCACAG ACTCTGTGGA GCCTGAGATA CGGCAGCATC CACTTGGTTC CCCCATGAAC 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011248498.1
Translation

Target ORF information:

RefSeq Version XM_011250196.1
Organism Mus musculus(House mouse)
Definition Mus musculus 5-hydroxytryptamine (serotonin) receptor 6 (Htr6), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011250196.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGTTCCAG AGCCCGGCCC TGTCAACAGT AGCACCCCAG CCTGGGGCCC CGGGCCACCG 
CCAGCCCCAG GGGGCAGCGG CTGGGTGGCC GCTGCGCTGT GCGTGGTCAT CGTGCTGACG 
GCAGCCGCCA ATTCGCTGCT GATCGCGCTC ATCTGCACGC AGCCCGCGCT GCGCAACACG 
TCTAACTTCT TCCTGGTGTC GCTCTTCACG TCGGACCTGA TGGTGGGATT GGTGGTGATG 
CCCCCAGCCA TGCTGAACGC GCTGTATGGG CGCTGGGTGC TAGCTCGCGG CCTCTGTCTG 
CTTTGGACCG CCTTCGACGT GATGTGCTGC AGCGCCTCCA TTCTCAACCT CTGCCTCATC 
AGCCTGGACC GCTACCTGCT CATCCTCTCG CCGCTGCGCT ACAAGCTGCG CATGACAGCC 
CCGCGTGCCC TGGCGCTCAT CCTGGGTGCC TGGAGCCTCG CCGCGCTGGC CTCCTTCCTG 
CCCCTCTTGC TGGGCTGGCA TGAACTGGGC AAAGCTCGAA CATCTGCCCC GGGCCAGTGC 
CGCCTATTGG CCAGCCTGCC TTATGTCCTC GTGGCGTCCG GCGTCACCTT TTTCCTGCCT 
TCGGGTGCCA TCTGCTTCAC CTACTGCAGG ATCTTGCTGG CTGCCCGCAA GCAGGCGGTG 
CAAGTGGCCT CGCTCACCAC GGGCACGGCT ACGGCTGGCC AGGCCTTGGA AACCTTGCAG 
GTGCCCAGGA CACCACGCCC AGGGATGGAG TCTGCTGACA GTAGGCGTCT GACCACCAAG 
CATAGCAGGA AGGCCTTGAA GGCCAGCCTG ACCCTCGGCA TCCTGCTGAG CATGTTCTTT 
GTCACCTGGC TGCCCTTCTT TGTGGCCAGC ATAGCTCAGG CCGTATGTGA CTGCATCTCT 
CCAGGTCTCT TCGATGTCCT CACATGGCTG GGATACTGTA ATAGCACCAT GAACCCTATC 
ATCTATCCCC TCTTCATGCG GGACTTCAAG AGGGCCCTGG GCAGGTTCGT GCCGTGTGTC 
CACTGTCCCC CGGAGCACCG GGCCAGCCCC GCCTCCCCCT CCATGTGGAC CTCTCACAGT 
GGTGCCAGGC CAGGCCTCAG CCTGCAGCAG GTGCTGCCCC TGCCTCTGCC ACCCAACTCA 
GATTCAGACT CAGCTTCAGG GGGCACCTCG GGCCTGCAGC TCACAGCCCA GCTTTTGCTG 
CCTGGAGAGG CGACCCGGGA CCCCCCGCCA CCCACCAGGG CCCCTACTGT GGTCAACTTC 
TTCGTCACAG ACTCTGTGGA GCCTGAGATA CGGCAGCATC CACTTGGTTC CCCCATGAAC 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu12234
Clone ID Related Accession (Same CDS sequence) XM_011250196.1 , NM_001377096.1 , XM_011250196.2 , NM_021358.2
Accession Version XM_011250196.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1323bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product 5-hydroxytryptamine receptor 6 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011250196.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGTTCCAG AGCCCGGCCC TGTCAACAGT AGCACCCCAG CCTGGGGCCC CGGGCCACCG 
CCAGCCCCAG GGGGCAGCGG CTGGGTGGCC GCTGCGCTGT GCGTGGTCAT CGTGCTGACG 
GCAGCCGCCA ATTCGCTGCT GATCGCGCTC ATCTGCACGC AGCCCGCGCT GCGCAACACG 
TCTAACTTCT TCCTGGTGTC GCTCTTCACG TCGGACCTGA TGGTGGGATT GGTGGTGATG 
CCCCCAGCCA TGCTGAACGC GCTGTATGGG CGCTGGGTGC TAGCTCGCGG CCTCTGTCTG 
CTTTGGACCG CCTTCGACGT GATGTGCTGC AGCGCCTCCA TTCTCAACCT CTGCCTCATC 
AGCCTGGACC GCTACCTGCT CATCCTCTCG CCGCTGCGCT ACAAGCTGCG CATGACAGCC 
CCGCGTGCCC TGGCGCTCAT CCTGGGTGCC TGGAGCCTCG CCGCGCTGGC CTCCTTCCTG 
CCCCTCTTGC TGGGCTGGCA TGAACTGGGC AAAGCTCGAA CATCTGCCCC GGGCCAGTGC 
CGCCTATTGG CCAGCCTGCC TTATGTCCTC GTGGCGTCCG GCGTCACCTT TTTCCTGCCT 
TCGGGTGCCA TCTGCTTCAC CTACTGCAGG ATCTTGCTGG CTGCCCGCAA GCAGGCGGTG 
CAAGTGGCCT CGCTCACCAC GGGCACGGCT ACGGCTGGCC AGGCCTTGGA AACCTTGCAG 
GTGCCCAGGA CACCACGCCC AGGGATGGAG TCTGCTGACA GTAGGCGTCT GACCACCAAG 
CATAGCAGGA AGGCCTTGAA GGCCAGCCTG ACCCTCGGCA TCCTGCTGAG CATGTTCTTT 
GTCACCTGGC TGCCCTTCTT TGTGGCCAGC ATAGCTCAGG CCGTATGTGA CTGCATCTCT 
CCAGGTCTCT TCGATGTCCT CACATGGCTG GGATACTGTA ATAGCACCAT GAACCCTATC 
ATCTATCCCC TCTTCATGCG GGACTTCAAG AGGGCCCTGG GCAGGTTCGT GCCGTGTGTC 
CACTGTCCCC CGGAGCACCG GGCCAGCCCC GCCTCCCCCT CCATGTGGAC CTCTCACAGT 
GGTGCCAGGC CAGGCCTCAG CCTGCAGCAG GTGCTGCCCC TGCCTCTGCC ACCCAACTCA 
GATTCAGACT CAGCTTCAGG GGGCACCTCG GGCCTGCAGC TCACAGCCCA GCTTTTGCTG 
CCTGGAGAGG CGACCCGGGA CCCCCCGCCA CCCACCAGGG CCCCTACTGT GGTCAACTTC 
TTCGTCACAG ACTCTGTGGA GCCTGAGATA CGGCAGCATC CACTTGGTTC CCCCATGAAC 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011248498.1
CDS658..1980
Translation

Target ORF information:

RefSeq Version XM_011250196.2
Organism Mus musculus(house mouse)
Definition Mus musculus 5-hydroxytryptamine (serotonin) receptor 6 (Htr6), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011250196.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGTTCCAG AGCCCGGCCC TGTCAACAGT AGCACCCCAG CCTGGGGCCC CGGGCCACCG 
CCAGCCCCAG GGGGCAGCGG CTGGGTGGCC GCTGCGCTGT GCGTGGTCAT CGTGCTGACG 
GCAGCCGCCA ATTCGCTGCT GATCGCGCTC ATCTGCACGC AGCCCGCGCT GCGCAACACG 
TCTAACTTCT TCCTGGTGTC GCTCTTCACG TCGGACCTGA TGGTGGGATT GGTGGTGATG 
CCCCCAGCCA TGCTGAACGC GCTGTATGGG CGCTGGGTGC TAGCTCGCGG CCTCTGTCTG 
CTTTGGACCG CCTTCGACGT GATGTGCTGC AGCGCCTCCA TTCTCAACCT CTGCCTCATC 
AGCCTGGACC GCTACCTGCT CATCCTCTCG CCGCTGCGCT ACAAGCTGCG CATGACAGCC 
CCGCGTGCCC TGGCGCTCAT CCTGGGTGCC TGGAGCCTCG CCGCGCTGGC CTCCTTCCTG 
CCCCTCTTGC TGGGCTGGCA TGAACTGGGC AAAGCTCGAA CATCTGCCCC GGGCCAGTGC 
CGCCTATTGG CCAGCCTGCC TTATGTCCTC GTGGCGTCCG GCGTCACCTT TTTCCTGCCT 
TCGGGTGCCA TCTGCTTCAC CTACTGCAGG ATCTTGCTGG CTGCCCGCAA GCAGGCGGTG 
CAAGTGGCCT CGCTCACCAC GGGCACGGCT ACGGCTGGCC AGGCCTTGGA AACCTTGCAG 
GTGCCCAGGA CACCACGCCC AGGGATGGAG TCTGCTGACA GTAGGCGTCT GACCACCAAG 
CATAGCAGGA AGGCCTTGAA GGCCAGCCTG ACCCTCGGCA TCCTGCTGAG CATGTTCTTT 
GTCACCTGGC TGCCCTTCTT TGTGGCCAGC ATAGCTCAGG CCGTATGTGA CTGCATCTCT 
CCAGGTCTCT TCGATGTCCT CACATGGCTG GGATACTGTA ATAGCACCAT GAACCCTATC 
ATCTATCCCC TCTTCATGCG GGACTTCAAG AGGGCCCTGG GCAGGTTCGT GCCGTGTGTC 
CACTGTCCCC CGGAGCACCG GGCCAGCCCC GCCTCCCCCT CCATGTGGAC CTCTCACAGT 
GGTGCCAGGC CAGGCCTCAG CCTGCAGCAG GTGCTGCCCC TGCCTCTGCC ACCCAACTCA 
GATTCAGACT CAGCTTCAGG GGGCACCTCG GGCCTGCAGC TCACAGCCCA GCTTTTGCTG 
CCTGGAGAGG CGACCCGGGA CCCCCCGCCA CCCACCAGGG CCCCTACTGT GGTCAACTTC 
TTCGTCACAG ACTCTGTGGA GCCTGAGATA CGGCAGCATC CACTTGGTTC CCCCATGAAC 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Serotonin 5-HT6 receptors affect cognition in a mouse model of Alzheimer's disease by regulating cilia function.
Alzheimer's research & therapy9(1)76(2017 Sep)
Hu L,Wang B,Zhang Y


book

5-HT
Brain research166010-19(2017 04)
Brodsky M,Lesiak AJ,Croicu A,Cohenca N,Sullivan JM,Neumaier JF