Igfbp5 cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Igfbp5 |
| Entrez Gene ID | 16011 |
| Full Name | insulin-like growth factor binding protein 5 |
| Synonyms | AI256729,AW208790,IGFBP-5,IGFBP-5P |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_010518.2 | NP_034648.2 | insulin-like growth factor-binding protein 5 precursor |
| Bos taurus (cattle) | IGFBP5 | NP_001098797.1 |
| Mus musculus (house mouse) | Igfbp5 | NP_034648.2 |
| Xenopus tropicalis (tropical clawed frog) | igfbp5 | NP_001016042.1 |
| Canis lupus familiaris (dog) | IGFBP5 | XP_852885.1 |
| Gallus gallus (chicken) | IGFBP5 | XP_422069.3 |
| IGFBP5 | XP_001087664.1 | |
| Danio rerio (zebrafish) | igfbp5b | NP_001092224.1 |
| Homo sapiens (human) | IGFBP5 | NP_000590.1 |
| Pan troglodytes (chimpanzee) | IGFBP5 | XP_003309513.1 |
| Rattus norvegicus (Norway rat) | Igfbp5 | NP_036949.1 |
| Danio rerio (zebrafish) | igfbp5a | NP_001119935.1 |
Related articles in PubMed
ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice.
Ho L, van Dijk M, Chye STJ, Messerschmidt DM, Chng SC, Ong S, Yi LK, Boussata S, Goh GH, Afink GB, Lim CY, Dunn NR, Solter D, Knowles BB, Reversade B
Science (New York, N.Y.)357(6352)707-713(2017 08)
The Wilms tumor protein WT1 stimulates transcription of the gene encoding insulin-like growth factor binding protein 5 (IGFBP5).
M?ller M, Persson AB, Krueger K, Kirschner KM, Scholz H
Gene61921-29(2017 Jul)
A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.
Bibollet-Bahena O, Okafuji T, Hokamp K, Tear G, Mitchell KJ
PloS one12(5)e0177977(2017)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data demonstrate that dysregulation of miR-143-3p:Igfbp5 interactions in satellite cells with age may be responsible for age-related changes in satellite cell function.
Title: Age-related changes in miR-143-3p:Igfbp5 interactions affect muscle regeneration.
proliferation of IGFBP5-mutated cancer cells is selectively blocked by IGF-1R inhibitors
Title: Secreted IGFBP5 mediates mTORC1-dependent feedback inhibition of IGF-1 signalling.
Results from mouse models suggest that inhibiting the up-regulation of IGFBP5 expression in peripheral nerves might prevent or slow down diabetic neuropathy disease progression
Title: Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathy.
IGFBP-5 induces its pro-fibrotic effects, at least in part, via DOK5. IGFBP-5 and DOK5 are both increased in systemic sclerosis fibroblasts and tissues and may thus be acting in concert to promote fibrosis.
Title: The membrane-associated adaptor protein DOK5 is upregulated in systemic sclerosis and associated with IGFBP-5-induced fibrosis.
Igfbp2-5 are expressed in distinct and complementary patterns during cochlear development.
Title: Expression of insulin-like growth factor binding proteins during mouse cochlear development.
The following Igfbp5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Igfbp5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu17958 | |
| Clone ID Related Accession (Same CDS sequence) | NM_010518.2 | |
| Accession Version | NM_010518.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-25 | |
| Organism | Mus musculus(house mouse) | |
| Product | insulin-like growth factor-binding protein 5 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC057447.1, BC029321.1 and BC018579.1. On Jul 16, 2005 this sequence version replaced NM_010518.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC057447.1, L12447.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849385, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGTGATCA GCGTGGTCCT CCTGCTGCTG GCCGCCTATG CCGTACCGGC TCAAGGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_034648.2 |
| CDS | 727..1542 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_010518.2 |
ORF Insert Sequence:
1 | ATGGTGATCA GCGTGGTCCT CCTGCTGCTG GCCGCCTATG CCGTACCGGC TCAAGGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice. |
|
The Wilms tumor protein WT1 stimulates transcription of the gene encoding insulin-like growth factor binding protein 5 (IGFBP5). |
|
A dual-strategy expression screen for candidate connectivity labels in the developing thalamus. |