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Irs1 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Irs1
Entrez Gene ID 16367
Full Name insulin receptor substrate 1
Synonyms G972R,IRS-1
General protein information
Preferred Names

insulin receptor substrate 1

Names

insulin receptor substrate 1
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

1

1 C5|1 42.0 cM

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_010570.4 NP_034700.2 insulin receptor substrate 1

Pathways from BioSystems


Homologies


Rattus norvegicus (Norway rat) Irs1 NP_037101.1
Gallus gallus (chicken) IRS1 XP_004951158.1
Homo sapiens (human) IRS1 NP_005535.1
Pan troglodytes (chimpanzee) IRS1 XP_001134895.1
Xenopus tropicalis (tropical clawed frog) LOC100495320 XP_004914519.1
Canis lupus familiaris (dog) IRS1 XP_543274.3
Danio rerio (zebrafish) irs1 XP_005157831.1
Bos taurus (cattle) IRS1 XP_003585821.1
Mus musculus (house mouse) Irs1 NP_034700.2

Gene Ontology

The following Irs1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Irs1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu21935 NM_010570.4
Latest version!		 Mus musculus insulin receptor substrate 1 (Irs1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 $643.30
$919.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu21935
Clone ID Related Accession (Same CDS sequence) NM_010570.4
Accession Version NM_010570.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 3696bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-26
Organism Mus musculus(house mouse)
Product insulin receptor substrate 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC137845.9 and AC123690.19. On Nov 27, 2007 this sequence version replaced NM_010570.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK045317.1, X69722.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN01164141 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
ATGGCGAGCC CTCCGGATAC CGATGGCTTC TCAGACGTGC GCAAGGTGGG CTACCTGCGC 
AAGCCCAAGA GTATGCATAA GCGCTTTTTC GTGCTGCGGG CGGCCAGCGA GGCCGGGGGC 
CCAGCGCGCC TGGAGTATTA TGAGAACGAG AAGAAGTGGC GGCACAAGTC GAGCGCCCCC 
AAACGCTCGA TCCCCCTCGA GAGCTGTTTC AACATCAACA AGCGGGCTGA CTCCAAGAAC 
AAGCACCTGG TGGCTCTCTA CACCCGAGAC GAACACTTTG CCATTGCCGC GGATAGCGAG 
GCTGAGCAAG ACAGCTGGTA CCAGGCTCTT CTGCAGCTGC ATAATCGGGC AAAGGCCCAC 
CATGACGGGG CTGGAGGAGG CTGCGGCGGT AGCTGCAGCG GCAGCTCTGG CGTTGGAGAG 
GCAGGGGAGG ACTTGAGCTA TGACACGGGT CCAGGACCCG CGTTCAAGGA GGTCTGGCAG 
GTTATCCTGA AACCCAAGGG CCTGGGTCAG ACAAAGAACC TGATTGGCAT CTACCGCCTC 
TGCCTGACCA GCAAGACCAT CAGCTTTGTG AAGCTGAACT CCGAGGCAGC CGCTGTGGTG 
CTGCAGCTGA TGAATATCAG ACGCTGTGGC CACTCAGAGA ACTTCTTCTT CATCGAGGTG 
GGGCGTTCCG CTGTGACAGG GCCTGGCGAG TTCTGGATGC AAGTGGATGA CTCCGTGGTG 
GCCCAGAACA TGCATGAGAC CATTCTAGAG GCAATGAGGG CCATGAGCGA TGAGTTTCGC 
CCTCGCAGCA AAAGCCAGTC TTCATCCAGT TGCTCCAACC CCATCAGCGT TCCCCTGCGC 
AGGCACCATC TCAACAACCC TCCACCCAGC CAGGTGGGAC TGACTCGGAG ATCTCGAACT 
GAGAGCATCA CTGCCACCTC CCCTGCCAGT ATGGTGGGTG GGAAACCAGG TTCCTTCCGG 
GTGCGTGCCT CCAGCGATGG CGAAGGCACC ATGTCCCGTC CAGCATCAGT GGATGGCAGT 
CCTGTGAGCC CTAGCACCAA CAGGACCCAC GCCCATCGGC ATCGAGGCAG CTCCAGGCTG 
CACCCCCCAC TCAACCACAG CCGCTCCATC CCCATGCCTT CTTCTAGATG CTCACCTTCA 
GCCACCAGCC CAGTGAGTCT GTCATCTAGT AGTACCAGTG GCCATGGCTC CACTTCAGAC 
TGTCTCTTCC CGAGGCGCTC TAGTGCTTCC GTGTCCGGTT CGCCTAGCGA TGGCGGTTTC 
ATCTCTTCTG ATGAGTATGG TTCTAGTCCC TGCGATTTCC GAAGTTCCTT CCGCAGTGTC 
ACCCCAGATT CCCTGGGGCA CACCCCACCA GCCAGGGGTG AGGAGGAGCT GAGCAATTAT 
ATCTGCATGG GTGGCAAGGG AGCCTCCACC TTGGCTGCTC CCAATGGCCA CTACATTTTG 
TCTAGGGGTG GCAACGGCCA TCGCTACATC CCAGGTGCTA ACTTGGGGAC AAGCCCAGCG 
CTGCCTGGAG ATGAAGCCGC GGGTGCAGCA GATCTGGATA ACCGGTTTCG AAAGAGAACT 
CACTCCGCAG GCACATCTCC TACCATTTCC CATCAGAAGA CCCCCTCACA GTCTTCAGTG 
GCTTCTATTG AGGAATATAC AGAGATGATG CCCGCTGCCT ACCCACCAGG AGGTGGCAGT 
GGAGGCCGAC TGCCCGGCTA CCGGCATTCC GCCTTCGTGC CCACCCACTC CTATCCCGAA 
GAGGGTCTAG AGATGCACCA CTTGGAACGT CGTGGAGGCC ACCACCGTCC AGACACCTCC 
AACCTCCACA CTGATGATGG CTATATGCCC ATGTCTCCTG GGGTGGCTCC AGTGCCCAGC 
AACCGCAAAG GAAATGGGGA CTATATGCCC ATGAGCCCCA AGAGTGTATC TGCCCCACAG 
CAGATCATTA ACCCCATCAG ACGCCACCCA CAGAGAGTGG ACCCCAATGG CTACATGATG 
ATGTCACCCA GTGGTAGTTG CTCCCCTGAC ATTGGAGGTG GGTCCAGCAG CAGTAGCAGC 
ATCAGCGCAG CCCCTTCTGG GAGCAGCTAT GGGAAGCCAT GGACAAATGG AGTAGGGGGG 
CACCATACTC ATGCCCTTCC TCATGCCAAA CCTCCTGTTG AGAGTGGTGG CGGTAAGCTC 
TTGCCTTGCA CAGGTGACTA CATGAACATG TCCCCAGTGG GAGATTCCAA CACCAGCAGC 
CCCTCAGAAT GCTACTATGG CCCAGAAGAT CCCCAGCACA AGCCGGTCCT CTCTTACTAC 
TCATTGCCAA GGTCCTTTAA GCACACCCAG CGCCCTGGAG AGCCAGAGGA GGGTGCCAGG 
CACCAGCATC TTCGTCTCTC TTCTAGCTCT GGACGCCTTC GCTATACCGC AACTGCCGAA 
GATTCCTCCT CTTCTACCAG CAGCGACAGT CTGGGTGGGG GTTACTGTGG GGCTAGGCCA 
GAGTCAAGCC TCACACATCC CCACCACCAT GTCTTGCAGC CCCACCTGCC TCGAAAGGTA 
GACACAGCTG CACAGACCAA CAGCCGCCTG GCTCGACCCA CAAGGCTGTC CTTGGGGGAT 
CCCAAGGCAA GCACCTTACC CCGGGTTCGA GAGCAGCAAC AGCAGCAGCA GTCTTCCCTG 
CACCCTCCCG AGCCCAAAAG CCCAGGAGAA TATGTGAATA TTGAATTCGG GAGCGGCCAG 
CCTGGCTATT TAGCTGGCCC TGCAACTTCC CGTAGCTCTC CTTCAGTTCG ATGTCCACCC 
CAGCTCCACC CAGCTCCTAG AGAAGAGACT GGCTCGGAAG AGTACATGAA CATGGACTTG 
GGGCCAGGCC GGAGGGCAAC CTGGCAGGAG AGTGGTGGAG TTGAGTTGGG CAGAATAGGC 
CCTGCACCTC CGGGGTCTGC TACGGTTTGC AGGCCAACCC GTTCGGTGCC AAATAGCCGT 
GGTGACTACA TGACCATGCA GATAGGTTGT CCTCGTCAAA GCTATGTGGA TACCTCACCA 
GTGGCCCCAG TCAGCTATGC TGACATGCGG ACAGGCATTG CTGCAGAGAA GGCGAGCCTG 
CCTAGACCCA CAGGAGCTGC TCCTCCTCCA TCCTCCACAG CCTCTTCTTC TGTTACACCT 
CAAGGAGCCA CCGCTGAGCA AGCTACTCAC TCTTCCTTGC TGGGAGGCCC TCAGGGACCT 
GGGGGCATGA GTGCATTCAC CAGGGTGAAC CTCAGTCCCA ACCATAACCA GAGTGCCAAA 
GTGATTCGCG CAGACACTCA AGGGTGCCGG AGGAGGCATA GCTCTGAGAC CTTCTCAGCA 
CCTACTCGGG CTGGCAATAC GGTGCCCTTT GGAGCAGGGG CTGCAGTAGG GGGCAGCGGC 
GGTGGTGGTG GTGGCGGCAG TGAGGATGTA AAACGCCACA GCTCTGCATC CTTTGAGAAT 
GTGTGGCTGA GACCTGGGGA TCTAGGGGGA GTCTCCAAGG AGTCGGCTCC AGTGTGTGGG 
GCTGCTGGGG GTTTGGAGAA GAGTCTTAAC TACATAGACC TGGATTTGGC CAAGGAGCGC 
TCTCAGGACT GCCCCTCTCA ACAGCAGTCC CTACCACCCC CTCCCCCTCA CCAGCCCTTA 
GGCAGCAATG AGGGCAACTC CCCAAGACGC TCCAGTGAGG ATTTAAGCAA CTATGCCAGC 
ATCAGCTTCC AGAAGCAGCC AGAGGATCGT CAATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_034700.2
CDS947..4642
Translation

Target ORF information:

RefSeq Version NM_010570.4
Organism Mus musculus(house mouse)
Definition Mus musculus insulin receptor substrate 1 (Irs1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_010570.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
ATGGCGAGCC CTCCGGATAC CGATGGCTTC TCAGACGTGC GCAAGGTGGG CTACCTGCGC 
AAGCCCAAGA GTATGCATAA GCGCTTTTTC GTGCTGCGGG CGGCCAGCGA GGCCGGGGGC 
CCAGCGCGCC TGGAGTATTA TGAGAACGAG AAGAAGTGGC GGCACAAGTC GAGCGCCCCC 
AAACGCTCGA TCCCCCTCGA GAGCTGTTTC AACATCAACA AGCGGGCTGA CTCCAAGAAC 
AAGCACCTGG TGGCTCTCTA CACCCGAGAC GAACACTTTG CCATTGCCGC GGATAGCGAG 
GCTGAGCAAG ACAGCTGGTA CCAGGCTCTT CTGCAGCTGC ATAATCGGGC AAAGGCCCAC 
CATGACGGGG CTGGAGGAGG CTGCGGCGGT AGCTGCAGCG GCAGCTCTGG CGTTGGAGAG 
GCAGGGGAGG ACTTGAGCTA TGACACGGGT CCAGGACCCG CGTTCAAGGA GGTCTGGCAG 
GTTATCCTGA AACCCAAGGG CCTGGGTCAG ACAAAGAACC TGATTGGCAT CTACCGCCTC 
TGCCTGACCA GCAAGACCAT CAGCTTTGTG AAGCTGAACT CCGAGGCAGC CGCTGTGGTG 
CTGCAGCTGA TGAATATCAG ACGCTGTGGC CACTCAGAGA ACTTCTTCTT CATCGAGGTG 
GGGCGTTCCG CTGTGACAGG GCCTGGCGAG TTCTGGATGC AAGTGGATGA CTCCGTGGTG 
GCCCAGAACA TGCATGAGAC CATTCTAGAG GCAATGAGGG CCATGAGCGA TGAGTTTCGC 
CCTCGCAGCA AAAGCCAGTC TTCATCCAGT TGCTCCAACC CCATCAGCGT TCCCCTGCGC 
AGGCACCATC TCAACAACCC TCCACCCAGC CAGGTGGGAC TGACTCGGAG ATCTCGAACT 
GAGAGCATCA CTGCCACCTC CCCTGCCAGT ATGGTGGGTG GGAAACCAGG TTCCTTCCGG 
GTGCGTGCCT CCAGCGATGG CGAAGGCACC ATGTCCCGTC CAGCATCAGT GGATGGCAGT 
CCTGTGAGCC CTAGCACCAA CAGGACCCAC GCCCATCGGC ATCGAGGCAG CTCCAGGCTG 
CACCCCCCAC TCAACCACAG CCGCTCCATC CCCATGCCTT CTTCTAGATG CTCACCTTCA 
GCCACCAGCC CAGTGAGTCT GTCATCTAGT AGTACCAGTG GCCATGGCTC CACTTCAGAC 
TGTCTCTTCC CGAGGCGCTC TAGTGCTTCC GTGTCCGGTT CGCCTAGCGA TGGCGGTTTC 
ATCTCTTCTG ATGAGTATGG TTCTAGTCCC TGCGATTTCC GAAGTTCCTT CCGCAGTGTC 
ACCCCAGATT CCCTGGGGCA CACCCCACCA GCCAGGGGTG AGGAGGAGCT GAGCAATTAT 
ATCTGCATGG GTGGCAAGGG AGCCTCCACC TTGGCTGCTC CCAATGGCCA CTACATTTTG 
TCTAGGGGTG GCAACGGCCA TCGCTACATC CCAGGTGCTA ACTTGGGGAC AAGCCCAGCG 
CTGCCTGGAG ATGAAGCCGC GGGTGCAGCA GATCTGGATA ACCGGTTTCG AAAGAGAACT 
CACTCCGCAG GCACATCTCC TACCATTTCC CATCAGAAGA CCCCCTCACA GTCTTCAGTG 
GCTTCTATTG AGGAATATAC AGAGATGATG CCCGCTGCCT ACCCACCAGG AGGTGGCAGT 
GGAGGCCGAC TGCCCGGCTA CCGGCATTCC GCCTTCGTGC CCACCCACTC CTATCCCGAA 
GAGGGTCTAG AGATGCACCA CTTGGAACGT CGTGGAGGCC ACCACCGTCC AGACACCTCC 
AACCTCCACA CTGATGATGG CTATATGCCC ATGTCTCCTG GGGTGGCTCC AGTGCCCAGC 
AACCGCAAAG GAAATGGGGA CTATATGCCC ATGAGCCCCA AGAGTGTATC TGCCCCACAG 
CAGATCATTA ACCCCATCAG ACGCCACCCA CAGAGAGTGG ACCCCAATGG CTACATGATG 
ATGTCACCCA GTGGTAGTTG CTCCCCTGAC ATTGGAGGTG GGTCCAGCAG CAGTAGCAGC 
ATCAGCGCAG CCCCTTCTGG GAGCAGCTAT GGGAAGCCAT GGACAAATGG AGTAGGGGGG 
CACCATACTC ATGCCCTTCC TCATGCCAAA CCTCCTGTTG AGAGTGGTGG CGGTAAGCTC 
TTGCCTTGCA CAGGTGACTA CATGAACATG TCCCCAGTGG GAGATTCCAA CACCAGCAGC 
CCCTCAGAAT GCTACTATGG CCCAGAAGAT CCCCAGCACA AGCCGGTCCT CTCTTACTAC 
TCATTGCCAA GGTCCTTTAA GCACACCCAG CGCCCTGGAG AGCCAGAGGA GGGTGCCAGG 
CACCAGCATC TTCGTCTCTC TTCTAGCTCT GGACGCCTTC GCTATACCGC AACTGCCGAA 
GATTCCTCCT CTTCTACCAG CAGCGACAGT CTGGGTGGGG GTTACTGTGG GGCTAGGCCA 
GAGTCAAGCC TCACACATCC CCACCACCAT GTCTTGCAGC CCCACCTGCC TCGAAAGGTA 
GACACAGCTG CACAGACCAA CAGCCGCCTG GCTCGACCCA CAAGGCTGTC CTTGGGGGAT 
CCCAAGGCAA GCACCTTACC CCGGGTTCGA GAGCAGCAAC AGCAGCAGCA GTCTTCCCTG 
CACCCTCCCG AGCCCAAAAG CCCAGGAGAA TATGTGAATA TTGAATTCGG GAGCGGCCAG 
CCTGGCTATT TAGCTGGCCC TGCAACTTCC CGTAGCTCTC CTTCAGTTCG ATGTCCACCC 
CAGCTCCACC CAGCTCCTAG AGAAGAGACT GGCTCGGAAG AGTACATGAA CATGGACTTG 
GGGCCAGGCC GGAGGGCAAC CTGGCAGGAG AGTGGTGGAG TTGAGTTGGG CAGAATAGGC 
CCTGCACCTC CGGGGTCTGC TACGGTTTGC AGGCCAACCC GTTCGGTGCC AAATAGCCGT 
GGTGACTACA TGACCATGCA GATAGGTTGT CCTCGTCAAA GCTATGTGGA TACCTCACCA 
GTGGCCCCAG TCAGCTATGC TGACATGCGG ACAGGCATTG CTGCAGAGAA GGCGAGCCTG 
CCTAGACCCA CAGGAGCTGC TCCTCCTCCA TCCTCCACAG CCTCTTCTTC TGTTACACCT 
CAAGGAGCCA CCGCTGAGCA AGCTACTCAC TCTTCCTTGC TGGGAGGCCC TCAGGGACCT 
GGGGGCATGA GTGCATTCAC CAGGGTGAAC CTCAGTCCCA ACCATAACCA GAGTGCCAAA 
GTGATTCGCG CAGACACTCA AGGGTGCCGG AGGAGGCATA GCTCTGAGAC CTTCTCAGCA 
CCTACTCGGG CTGGCAATAC GGTGCCCTTT GGAGCAGGGG CTGCAGTAGG GGGCAGCGGC 
GGTGGTGGTG GTGGCGGCAG TGAGGATGTA AAACGCCACA GCTCTGCATC CTTTGAGAAT 
GTGTGGCTGA GACCTGGGGA TCTAGGGGGA GTCTCCAAGG AGTCGGCTCC AGTGTGTGGG 
GCTGCTGGGG GTTTGGAGAA GAGTCTTAAC TACATAGACC TGGATTTGGC CAAGGAGCGC 
TCTCAGGACT GCCCCTCTCA ACAGCAGTCC CTACCACCCC CTCCCCCTCA CCAGCCCTTA 
GGCAGCAATG AGGGCAACTC CCCAAGACGC TCCAGTGAGG ATTTAAGCAA CTATGCCAGC 
ATCAGCTTCC AGAAGCAGCC AGAGGATCGT CAATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed