Krt27 cDNA ORF clone, Mus musculus(house mouse)
Gene Symbol | Krt27 |
Entrez Gene ID | 16675 |
Full Name | keratin 27 |
Synonyms | CK-27,Krt1-c29,mIRSa3.1,stpm |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome | |
Summary | This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The mouse type I keratin genes are clustered in a region of chromosome 11. The encoded protein is involved in the formation of intermediate filaments in the inner root sheath. [provided by RefSeq, Sep 2015]. |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
NM_010666.2 | NP_034796.1 | keratin, type I cytoskeletal 27 |

Homo sapiens (human) | KRT27 | NP_853515.2 |
Pan troglodytes (chimpanzee) | KRT27 | XP_523630.2 |
LOC100430195 | XP_002800554.1 | |
Canis lupus familiaris (dog) | KRT27 | XP_548127.1 |
Bos taurus (cattle) | KRT27 | NP_001069283.1 |
Rattus norvegicus (Norway rat) | Krt27 | NP_001008824.1 |
Xenopus tropicalis (tropical clawed frog) | krt16 | XP_004918756.1 |
Mus musculus (house mouse) | Krt27 | NP_034796.1 |

Related articles in PubMed
Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.
Fairfield H, Srivastava A, Ananda G, Liu R, Kircher M, Lakshminarayana A, Harris BS, Karst SY, Dionne LA, Kane CC, Curtain M, Berry ML, Ward-Bailey PF, Greenstein I, Byers C, Czechanski A, Sharp J, Palmer K, Gudis P, Martin W, Tadenev A, Bogdanik L, Pratt CH, Chang B, Schroeder DG, Cox GA, Cliften P, Milbrandt J, Murray S, Burgess R, Bergstrom DE, Donahue LR, Hamamy H, Masri A, Santoni FA, Makrythanasis P, Antonarakis SE, Shendure J, Reinholdt LG
Genome research25(7)948-57(2015 Jul)
Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament.
Tanaka S, Miura I, Yoshiki A, Kato Y, Yokoyama H, Shinogi A, Masuya H, Wakana S, Tamura M, Shiroishi T
Genomics90(6)703-11(2007 Dec)
K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) represent the type I inner root sheath keratins of the human hair follicle.
Langbein L, Rogers MA, Praetzel-Wunder S, Helmke B, Schirmacher P, Schweizer J
The Journal of investigative dermatology126(11)2377-86(2006 Nov)
New consensus nomenclature for mammalian keratins.
Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW
The Journal of cell biology174(2)169-74(2006 Jul)
The dominant alopecia phenotypes Bareskin, Rex-denuded, and Reduced Coat 2 are caused by mutations in gasdermin 3.
Runkel F, Marquardt A, Stoeger C, Kochmann E, Simon D, Kohnke B, Korthaus D, Wattler F, Fuchs H, Hrab? de Angelis M, Stumm G, Nehls M, Wattler S, Franz T, Augustin M
Genomics84(5)824-35(2004 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Krt27 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Krt27 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu06571 | |
Clone ID Related Accession (Same CDS sequence) | NM_010666.2 | |
Accession Version | NM_010666.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1347bp) Protein sequence SNP |
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Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Mus musculus(house mouse) | |
Product | keratin, type I cytoskeletal 27 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL590991.14, AK077384.1 and AA756799.1. On Sep 16, 2015 this sequence version replaced NM_010666.1. ##Evidence-Data-START## Transcript exon combination :: BC140996.1, AK077384.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849383, SAMN00849384 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCCGTTC GCTTTTCTTC CGCATCCAGA CGGCTGGGCT CTGTGAGGCT CTCCAGCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_034796.1 |
CDS | 46..1392 |
Translation |

Target ORF information:
Target ORF information:
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ORF Insert Sequence:
1 | ATGTCCGTTC GCTTTTCTTC CGCATCCAGA CGGCTGGGCT CTGTGAGGCT CTCCAGCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
![]() |
Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders. |
![]() |
Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament. |
![]() |
K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) represent the type I inner root sheath keratins of the human hair follicle. |
![]() |
New consensus nomenclature for mammalian keratins. |
![]() |
The dominant alopecia phenotypes Bareskin, Rex-denuded, and Reduced Coat 2 are caused by mutations in gasdermin 3. |