Ly6c1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Gene Symbol	Ly6c1
Entrez Gene ID	17067
Full Name	lymphocyte antigen 6 complex, locus C1
Synonyms	AA682074,AA959465,Ly-6C,Ly-6C1,Ly6c
General protein information	Preferred Names lymphocyte antigen 6 complex, locus C1 Names lymphocyte antigen 6C1 Lymphocyte antigen Ly-6C lymphocyte antigen 6 complex, locus C
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15 D3\|15 34.29 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006520521.3	XP_006520584.1	lymphocyte antigen 6C1 isoform X1
NM_001252056.1	NP_001238985.1	lymphocyte antigen 6C1 isoform 2 precursor
XM_006520521.4	XP_006520584.1	lymphocyte antigen 6C1 isoform X1
NM_001252055.1	NP_001238984.1	lymphocyte antigen 6C1 isoform 1 precursor
NM_001252057.1	NP_001238986.1	lymphocyte antigen 6C1 isoform 3 precursor
NM_001252058.1	NP_001238987.1	lymphocyte antigen 6C1 isoform 3 precursor
XM_030248358.1	XP_030104218.1	lymphocyte antigen 6C1 isoform X2
NM_010741.3	NP_034871.2	lymphocyte antigen 6C1 isoform 1 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Ly6i	NP_065244.2
Mus musculus (house mouse)	Ly6c2	NP_001092687.1
Rattus norvegicus (Norway rat)	LOC300024	XP_216959.1
Rattus norvegicus (Norway rat)	Ly6c	NP_064488.1
Rattus norvegicus (Norway rat)	Ly6i	NP_640350.1
Mus musculus (house mouse)	Ly6c1	NP_001238984.1
Mus musculus (house mouse)	Ly6a	NP_034868.1
Mus musculus (house mouse)	Ly6f	NP_032556.1
Rattus norvegicus (Norway rat)	Ly6al	NP_001121571.1
Rattus norvegicus (Norway rat)	RGD1565410	XP_006241832.1
Mus musculus (house mouse)	Ly6g	XP_006521677.1
Mus musculus (house mouse)	I830127L07Rik	XP_001477152.1
Rattus norvegicus (Norway rat)	LOC100911104	XP_003751391.1

Gene Ontology
Bibliography

Related articles in PubMed

Cytokine- and TCR-Mediated Regulation of T Cell Expression of Ly6C and Sca-1.
DeLong JH, Hall AO, Konradt C, Coppock GM, Park J, Harms Pritchard G, Hunter CA
Journal of immunology (Baltimore, Md. : 1950)(2018 Jan)

Ly6C
Schloss MJ, Hilby M, Nitz K, Guillamat Prats R, Ferraro B, Leoni G, Soehnlein O, Kessler T, He W, Luckow B, Horckmans M, Weber C, Duchene J, Steffens S
Arteriosclerosis, thrombosis, and vascular biology37(9)1640-1645(2017 Sep)

Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.
Jung K, Heishi T, Khan OF, Kowalski PS, Incio J, Rahbari NN, Chung E, Clark JW, Willett CG, Luster AD, Yun SH, Langer R, Anderson DG, Padera TP, Jain RK, Fukumura D
The Journal of clinical investigation127(8)3039-3051(2017 Aug)

Splenic Ly6C
Tomczyk M, Kraszewska I, Szade K, Bukowska-Strakova K, Meloni M, Jozkowicz A, Dulak J, Jazwa A
Basic research in cardiology112(4)39(2017 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

surface expression on Ly6C(high) monocytes changes in a time-of-day-dependent manner, which crucially affects cardiac monocyte recruitment after an acute ischemic event.
Title: Ly6C

CX3CL1 is upregulated in both human and murine tumors following VEGF signaling blockade, resulting in recruitment of CX3CR1+Ly6Clo monocytes into the tumor
Title: Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.

monocyte differentiation occurred through de novo enhancer establishment and activation of pre-established (poised) enhancers. Generation of Ly6C(-) monocytes involved induction of the transcription factor C/EBPbeta and C/EBPbeta-deficient mice lacked Ly6C(-) monocytes.
Title: Genomic Characterization of Murine Monocytes Reveals C/EBP? Transcription Factor Dependence of Ly6C

Ly6C, 4-1BB, and KLRG1 have roles in the activation of lamina propria lymphocytes in the small intestine in a mouse model of Crohn's disease
Title: Involvement of Ly6C, 4-1BB, and KLRG1 in the activation of lamina propria lymphocytes in the small intestine of sanroque mice.

The adapter Mal (encoded by TIRAP) has appeared crucial for the cytokine production by Ly6C(lo) but not by Ly6C(hi) monocytes. The protein Mal was necessary to induce cytokine synthesis by Ly6C(lo) monocytes after triggering TLR2 or TLR9.
Title: MyD88 Adapter-like (Mal)/TIRAP Is Required for Cytokine Production by Splenic Ly6CloTLR2hi but Not by Ly6ChiTLR2hi Monocytes during Trypanosoma cruzi Infection.

The following Ly6c1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ly6c1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu15686	NM_010741.3 Latest version!	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu15686	NM_001252055.1 Latest version!	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu15886	NM_001252058.1 Latest version!	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu15886	NM_001252057.1 Latest version!	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu16210	NM_001252056.1 Latest version!	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu15686	XM_006520521.4 Latest version!	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu15886	XM_030248358.1 Latest version!	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu15686	XM_006520521.3	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ly6c1 ( NM_001252055.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001238984.1 Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu15686
Clone ID Related Accession (Same CDS sequence)	XM_006520521.3 , XM_006520521.4 , NM_001252055.1 , NM_010741.3
Accession Version	NM_001252055.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-30
Organism	Mus musculus(house mouse)
Product	lymphocyte antigen 6C1 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB595639.1, AK143577.1 and BQ175080.1. Transcript Variant: This variant (2) has an additional segment in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK143577.1, SRR1660813.373001.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END##

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGACT CTCAAAGAAG GAAACTAAAG ACCCGTCAGT GCCTTTCTTT CTGCCCTGCT 
GGTGTGCCAA TCAGGGATCC TAACATCAGG GAGAGGACTT CCTGTTGCAG CGAAGACCTC 
TGCAATGCAG CAGTTCCCAC TGCAGGTAGC ACCTGGACCA TGGCAGGGGT GCTTCTGTTC 
AGCCTGAGCT CAGTCGTCCT GCAGACCTTG CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001238984.1
CDS	82..477
Translation	MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL

Target ORF information:

RefSeq Version	NM_001252055.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001252055.1

ORF Insert Sequence:

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGACT CTCAAAGAAG GAAACTAAAG ACCCGTCAGT GCCTTTCTTT CTGCCCTGCT 
GGTGTGCCAA TCAGGGATCC TAACATCAGG GAGAGGACTT CCTGTTGCAG CGAAGACCTC 
TGCAATGCAG CAGTTCCCAC TGCAGGTAGC ACCTGGACCA TGGCAGGGGT GCTTCTGTTC 
AGCCTGAGCT CAGTCGTCCT GCAGACCTTG CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ly6c1 ( NM_010741.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034871.2 Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu15686
Clone ID Related Accession (Same CDS sequence)	XM_006520521.3 , XM_006520521.4 , NM_001252055.1 , NM_010741.3
Accession Version	NM_010741.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-30
Organism	Mus musculus(house mouse)
Product	lymphocyte antigen 6C1 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB595639.1, BY118129.1, AK143577.1 and BQ175080.1. On Nov 3, 2011 this sequence version replaced NM_010741.2. Transcript Variant: This variant (1) is the predominant transcript and encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC010764.1, DV065761.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGACT CTCAAAGAAG GAAACTAAAG ACCCGTCAGT GCCTTTCTTT CTGCCCTGCT 
GGTGTGCCAA TCAGGGATCC TAACATCAGG GAGAGGACTT CCTGTTGCAG CGAAGACCTC 
TGCAATGCAG CAGTTCCCAC TGCAGGTAGC ACCTGGACCA TGGCAGGGGT GCTTCTGTTC 
AGCCTGAGCT CAGTCGTCCT GCAGACCTTG CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034871.2
CDS	67..462
Translation	MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL

Target ORF information:

RefSeq Version	NM_010741.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010741.3

ORF Insert Sequence:

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGACT CTCAAAGAAG GAAACTAAAG ACCCGTCAGT GCCTTTCTTT CTGCCCTGCT 
GGTGTGCCAA TCAGGGATCC TAACATCAGG GAGAGGACTT CCTGTTGCAG CGAAGACCTC 
TGCAATGCAG CAGTTCCCAC TGCAGGTAGC ACCTGGACCA TGGCAGGGGT GCTTCTGTTC 
AGCCTGAGCT CAGTCGTCCT GCAGACCTTG CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ly6c1 ( XM_006520521.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520584.1 Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu15686
Clone ID Related Accession (Same CDS sequence)	XM_006520521.3 , XM_006520521.4 , NM_001252055.1 , NM_010741.3
Accession Version	XM_006520521.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	lymphocyte antigen 6C1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006520521.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGACT CTCAAAGAAG GAAACTAAAG ACCCGTCAGT GCCTTTCTTT CTGCCCTGCT 
GGTGTGCCAA TCAGGGATCC TAACATCAGG GAGAGGACTT CCTGTTGCAG CGAAGACCTC 
TGCAATGCAG CAGTTCCCAC TGCAGGTAGC ACCTGGACCA TGGCAGGGGT GCTTCTGTTC 
AGCCTGAGCT CAGTCGTCCT GCAGACCTTG CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520584.1
CDS	114..509
Translation	MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL

Target ORF information:

RefSeq Version	XM_006520521.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520521.3

ORF Insert Sequence:

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGACT CTCAAAGAAG GAAACTAAAG ACCCGTCAGT GCCTTTCTTT CTGCCCTGCT 
GGTGTGCCAA TCAGGGATCC TAACATCAGG GAGAGGACTT CCTGTTGCAG CGAAGACCTC 
TGCAATGCAG CAGTTCCCAC TGCAGGTAGC ACCTGGACCA TGGCAGGGGT GCTTCTGTTC 
AGCCTGAGCT CAGTCGTCCT GCAGACCTTG CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ly6c1 ( NM_001252057.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001238986.1 Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu15886
Clone ID Related Accession (Same CDS sequence)	NM_001252057.1 , NM_001252058.1 , XM_030248358.1
Accession Version	NM_001252057.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 246bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-30
Organism	Mus musculus(house mouse)
Product	lymphocyte antigen 6C1 isoform 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB595639.1, AI893484.1 and AC124637.10. Transcript Variant: This variant (4) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AI893484.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849382 [ECO:0000348] ##Evidence-Data-END##

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGGGT CTCACTCTAA CCTCAGGATA GACTACAAGT CCCCATGTAG CCCAGTTTGG 
GATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001238986.1
CDS	67..312
Translation	MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEGSHSNLRIDYKSPCSPVWD

Target ORF information:

RefSeq Version	NM_001252057.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001252057.1

ORF Insert Sequence:

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGGGT CTCACTCTAA CCTCAGGATA GACTACAAGT CCCCATGTAG CCCAGTTTGG 
GATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ly6c1 ( NM_001252058.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001238987.1 Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OMu15886
Clone ID Related Accession (Same CDS sequence)	NM_001252057.1 , NM_001252058.1 , XM_030248358.1
Accession Version	NM_001252058.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 246bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-30
Organism	Mus musculus(house mouse)
Product	lymphocyte antigen 6C1 isoform 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BE448813.1 and AC124637.10. Transcript Variant: This variant (5) differs in the 5' and 3' UTRs as well as in the 3' coding region, compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus, compared to isoform 1. Variants 4 and 5 encode the same isoform 3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BE448813.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END##

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGGGT CTCACTCTAA CCTCAGGATA GACTACAAGT CCCCATGTAG CCCAGTTTGG 
GATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001238987.1
CDS	153..398
Translation	MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEGSHSNLRIDYKSPCSPVWD

Target ORF information:

RefSeq Version	NM_001252058.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001252058.1

ORF Insert Sequence:

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGGGT CTCACTCTAA CCTCAGGATA GACTACAAGT CCCCATGTAG CCCAGTTTGG 
GATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ly6c1 ( NM_001252056.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001238985.1 Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu16210
Clone ID Related Accession (Same CDS sequence)	NM_001252056.1
Accession Version	NM_001252056.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-30
Organism	Mus musculus(house mouse)
Product	lymphocyte antigen 6C1 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB595639.1, CK031980.1 and AC124637.10. Transcript Variant: This variant (3) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (3) has a longer and distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849382 [ECO:0000348] ##Evidence-Data-END##

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGACT CTCAAAGAAG GAAACTAAAG ACCCGTCAGT GCCTTTCTTT CTGCCCTGCT 
GGTGTGCCAA TCAGGGATCC TAACATCAGG GAGAGGACTT CCTGTTGCAG CGAAGACCTC 
TGCAATGCAG CAGTTCCCAC TGCAGGAATC CAGGGCCTCA TGCGTGTGAA GAAGCATCAT 
CAAGCACACA TCAGCACAGG GCACTTCCAA GGAGACCCTG CTTGTGGTGG GGAAGCCCAG 
GAGATGAGCA ATCAAAGGTT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001238985.1
CDS	67..510
Translation	MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGIQGLMRVKKHHQAHISTGHFQGDPACGGEAQEMSNQRL

Target ORF information:

RefSeq Version	NM_001252056.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001252056.1

ORF Insert Sequence:

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGACT CTCAAAGAAG GAAACTAAAG ACCCGTCAGT GCCTTTCTTT CTGCCCTGCT 
GGTGTGCCAA TCAGGGATCC TAACATCAGG GAGAGGACTT CCTGTTGCAG CGAAGACCTC 
TGCAATGCAG CAGTTCCCAC TGCAGGAATC CAGGGCCTCA TGCGTGTGAA GAAGCATCAT 
CAAGCACACA TCAGCACAGG GCACTTCCAA GGAGACCCTG CTTGTGGTGG GGAAGCCCAG 
GAGATGAGCA ATCAAAGGTT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ly6c1 ( XM_006520521.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520584.1 Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu15686
Clone ID Related Accession (Same CDS sequence)	XM_006520521.3 , XM_006520521.4 , NM_001252055.1 , NM_010741.3
Accession Version	XM_006520521.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	lymphocyte antigen 6C1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006520521.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGACT CTCAAAGAAG GAAACTAAAG ACCCGTCAGT GCCTTTCTTT CTGCCCTGCT 
GGTGTGCCAA TCAGGGATCC TAACATCAGG GAGAGGACTT CCTGTTGCAG CGAAGACCTC 
TGCAATGCAG CAGTTCCCAC TGCAGGTAGC ACCTGGACCA TGGCAGGGGT GCTTCTGTTC 
AGCCTGAGCT CAGTCGTCCT GCAGACCTTG CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520584.1
CDS	130..525
Translation	MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL

Target ORF information:

RefSeq Version	XM_006520521.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520521.4

ORF Insert Sequence:

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGACT CTCAAAGAAG GAAACTAAAG ACCCGTCAGT GCCTTTCTTT CTGCCCTGCT 
GGTGTGCCAA TCAGGGATCC TAACATCAGG GAGAGGACTT CCTGTTGCAG CGAAGACCTC 
TGCAATGCAG CAGTTCCCAC TGCAGGTAGC ACCTGGACCA TGGCAGGGGT GCTTCTGTTC 
AGCCTGAGCT CAGTCGTCCT GCAGACCTTG CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ly6c1 ( XM_030248358.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030104218.1 Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu15886
Clone ID Related Accession (Same CDS sequence)	NM_001252057.1 , NM_001252058.1 , XM_030248358.1
Accession Version	XM_030248358.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 246bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	lymphocyte antigen 6C1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGGGT CTCACTCTAA CCTCAGGATA GACTACAAGT CCCCATGTAG CCCAGTTTGG 
GATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030104218.1
CDS	165..410
Translation	MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEGSHSNLRIDYKSPCSPVWD

Target ORF information:

RefSeq Version	XM_030248358.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte antigen 6 complex, locus C1 (Ly6c1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030248358.1

ORF Insert Sequence:

ATGGACACTT CTCACACTAC AAAGTCCTGT GTGCTCATTC TTCTTGTGGC CCTACTGTGT 
GCAGAAAGAG CTCAGGGACT GCAGTGCTAC GAGTGCTATG GAGTGCCAAT TGAGACTTCC 
TGCCCAGCAG TTACCTGCCG CGCCTCTGAT GGATTCTGCA TTGCTCAAAA CATAGAATTG 
ATTGAGGGGT CTCACTCTAA CCTCAGGATA GACTACAAGT CCCCATGTAG CCCAGTTTGG 
GATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cytokine- and TCR-Mediated Regulation of T Cell Expression of Ly6C and Sca-1.
Journal of immunology (Baltimore, Md. : 1950)(2018 Jan)
DeLong JH,Hall AO,Konradt C,Coppock GM,Park J,Harms Pritchard G,Hunter CA

Ly6C
Arteriosclerosis, thrombosis, and vascular biology37(9)1640-1645(2017 Sep)
Schloss MJ,Hilby M,Nitz K,Guillamat Prats R,Ferraro B,Leoni G,Soehnlein O,Kessler T,He W,Luckow B,Horckmans M,Weber C,Duchene J,Steffens S

Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.
The Journal of clinical investigation127(8)3039-3051(2017 Aug)
Jung K,Heishi T,Khan OF,Kowalski PS,Incio J,Rahbari NN,Chung E,Clark JW,Willett CG,Luster AD,Yun SH,Langer R,Anderson DG,Padera TP,Jain RK,Fukumura D

Splenic Ly6C
Basic research in cardiology112(4)39(2017 Jul)
Tomczyk M,Kraszewska I,Szade K,Bukowska-Strakova K,Meloni M,Jozkowicz A,Dulak J,Jazwa A

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Ly6c1 cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

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