Gene Symbol | Sumo2 |
Entrez Gene ID | 170930 |
Full Name | small ubiquitin-like modifier 2 |
Synonyms | SUMO-2,Smt3A,Smt3b,Smt3h2 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Sumo2 cDNA ORF clone
gRNAs
Gene Symbol | Sumo2 |
Entrez Gene ID | 170930 |
Full Name | small ubiquitin-like modifier 2 |
Synonyms | SUMO-2,Smt3A,Smt3b,Smt3h2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_133354.2 | NP_579932.1 | small ubiquitin-related modifier 2 precursor |
Pan troglodytes (chimpanzee) | SUMO2 | XP_511671.2 |
Mus musculus (house mouse) | Sumo2 | NP_579932.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP001701 | XP_321390.3 |
Homo sapiens (human) | SUMO2 | NP_008868.3 |
Bos taurus (cattle) | SUMO2 | NP_777194.1 |
Danio rerio (zebrafish) | sumo2b | NP_001003422.1 |
Xenopus tropicalis (tropical clawed frog) | sumo2 | NP_001016406.1 |
Canis lupus familiaris (dog) | SUMO2 | NP_001239218.1 |
Rattus norvegicus (Norway rat) | Sumo2 | NP_598278.1 |
LOC694763 | XP_001082298.1 | |
Gallus gallus (chicken) | SUMO2 | NP_001074186.1 |
Temporal and SUMO-specific SUMOylation contribute to the dynamics of Polo-like kinase 1 (PLK1) and spindle integrity during mouse oocyte meiosis.
Feitosa WB, Hwang K, Morris PL
Developmental biology(2017 Dec)
Foxp1 regulation of neonatal vocalizations via cortical development.
Usui N, Araujo DJ, Kulkarni A, Co M, Ellegood J, Harper M, Toriumi K, Lerch JP, Konopka G
Genes & development31(20)2039-2055(2017 Oct)
Sumoylation-independent activation of Calcineurin-NFAT-signaling via SUMO2 mediates cardiomyocyte hypertrophy.
Bernt A, Rangrez AY, Eden M, Jungmann A, Katz S, Rohr C, M?ller OJ, Katus HA, Sossalla ST, Williams T, Ritter O, Frank D, Frey N
Scientific reports635758(2016 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
a regulatory role of ZNF451-1 in fine-tuning physiological PML levels
Title: The SUMO2/3 specific E3 ligase ZNF451-1 regulates PML stability.
SUMO-2-Tg mouse lines exhibited cardiomyopathy with various severities. SUMO-2 directly regulated apoptosis by at least partially targeting calpain 2 and calpastatin.
Title: Involvement of activated SUMO-2 conjugation in cardiomyopathy.
SUMO-2 inhibits aggregation of CPEB3.
Title: SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3.
Expression levels and not functional differences between SUMO2 and SUMO3 are critical for normal embryogenesis.
Title: SUMO2 is essential while SUMO3 is dispensable for mouse embryonic development.
Results indicate that a functional SUMO1-3 expression is essential for emotionality and cognition
Title: Neuron-specific Sumo1-3 knockdown in mice impairs episodic and fear memories.
The following Sumo2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sumo2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu15140 | |
Clone ID Related Accession (Same CDS sequence) | NM_133354.2 | |
Accession Version | NM_133354.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 288bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-15 | |
Organism | Mus musculus(house mouse) | |
Product | small ubiquitin-related modifier 2 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK012619.1. On Apr 6, 2007 this sequence version replaced NM_133354.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK012619.1, AK167308.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164140 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCGACG AGAAACCCAA GGAAGGAGTC AAGACTGAGA ACAACGATCA TATTAATTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_579932.1 |
CDS | 113..400 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGCCGACG AGAAACCCAA GGAAGGAGTC AAGACTGAGA ACAACGATCA TATTAATTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Temporal and SUMO-specific SUMOylation contribute to the dynamics of Polo-like kinase 1 (PLK1) and spindle integrity during mouse oocyte meiosis. |
Foxp1 regulation of neonatal vocalizations via cortical development. |
Sumoylation-independent activation of Calcineurin-NFAT-signaling via SUMO2 mediates cardiomyocyte hypertrophy. |