Gene Symbol | Gpr37l1 |
Entrez Gene ID | 171469 |
Full Name | G protein-coupled receptor 37-like 1 |
Synonyms | AW047233,CAG-18,D0Kist8 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Gpr37l1 cDNA ORF clone
Gene Symbol | Gpr37l1 |
Entrez Gene ID | 171469 |
Full Name | G protein-coupled receptor 37-like 1 |
Synonyms | AW047233,CAG-18,D0Kist8 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_134438.3 | NP_602320.2 | G-protein coupled receptor 37-like 1 precursor |
Homo sapiens (human) | GPR37L1 | NP_004758.3 |
Rattus norvegicus (Norway rat) | Gpr37l1 | NP_665727.2 |
GPR37L1 | XP_001106794.1 | |
Canis lupus familiaris (dog) | GPR37L1 | XP_849000.3 |
Mus musculus (house mouse) | Gpr37l1 | NP_602320.2 |
Gallus gallus (chicken) | GPR37L1 | XP_419256.4 |
Danio rerio (zebrafish) | gpr37l1b | XP_696192.2 |
Xenopus tropicalis (tropical clawed frog) | gpr37l1 | NP_001072523.1 |
Pan troglodytes (chimpanzee) | GPR37L1 | XP_514100.2 |
Bos taurus (cattle) | GPR37L1 | NP_001069367.1 |
G protein-coupled receptor 37-like 1 modulates astrocyte glutamate transporters and neuronal NMDA receptors and is neuroprotective in ischemia.
Jolly S, Bazargani N, Quiroga AC, Pringle NP, Attwell D, Richardson WD, Li H
Glia66(1)47-61(2018 Jan)
GPR37L1 modulates seizure susceptibility: Evidence from mouse studies and analyses of a human GPR37L1 variant.
Giddens MM, Wong JC, Schroeder JP, Farrow EG, Smith BM, Owino S, Soden SE, Meyer RC, Saunders C, LePichon JB, Weinshenker D, Escayg A, Hall RA
Neurobiology of disease106181-190(2017 Oct)
Mice lacking Gpr37 exhibit decreased expression of the myelin-associated glycoprotein MAG and increased susceptibility to demyelination.
Smith BM, Giddens MM, Neil J, Owino S, Nguyen TT, Duong D, Li F, Hall RA
Neuroscience35849-57(2017 Sep)
GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin.
Meyer RC, Giddens MM, Schaefer SA, Hall RA
Proceedings of the National Academy of Sciences of the United States of America110(23)9529-34(2013 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Gpr37l1 participates in the regulation of sonic hedgehog signaling during postnatal cerebellar development.
Title: Precocious cerebellum development and improved motor functions in mice lacking the astrocyte cilium-, patched 1-associated Gpr37l1 receptor.
The following Gpr37l1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gpr37l1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu21226 | |
Clone ID Related Accession (Same CDS sequence) | NM_134438.3 | |
Accession Version | NM_134438.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1446bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Mus musculus(house mouse) | |
Product | G-protein coupled receptor 37-like 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK158275.1, BY727284.1, BC127619.1 and CD774808.1. On Dec 13, 2007 this sequence version replaced NM_134438.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB016602.1, AK158275.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCGGTGGC TGTGGCCCCT GGCTGTGTCT CTTGTTGTAG TGTTGACTGT GGGGCTGAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_602320.2 |
CDS | 178..1623 |
Translation |
Target ORF information:
Target ORF information:
|
NM_134438.3 |
1 | ATGCGGTGGC TGTGGCCCCT GGCTGTGTCT CTTGTTGTAG TGTTGACTGT GGGGCTGAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
G protein-coupled receptor 37-like 1 modulates astrocyte glutamate transporters and neuronal NMDA receptors and is neuroprotective in ischemia. |
GPR37L1 modulates seizure susceptibility: Evidence from mouse studies and analyses of a human GPR37L1 variant. |
Mice lacking Gpr37 exhibit decreased expression of the myelin-associated glycoprotein MAG and increased susceptibility to demyelination. |
GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin. |