Gene Symbol | Foxk1 |
Entrez Gene ID | 17425 |
Full Name | forkhead box K1 |
Synonyms | A630048H08Rik,AI463295,Gm10868,Mnf |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Foxk1 cDNA ORF clone
Gene Symbol | Foxk1 |
Entrez Gene ID | 17425 |
Full Name | forkhead box K1 |
Synonyms | A630048H08Rik,AI463295,Gm10868,Mnf |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006504654.2 | XP_006504717.1 | forkhead box protein K1 isoform X1 |
NM_199068.2 | NP_951031.2 | forkhead box protein K1 |
Homo sapiens (human) | FOXK1 | NP_001032242.1 |
Canis lupus familiaris (dog) | FOXK1 | XP_005621202.1 |
Mus musculus (house mouse) | Foxk1 | NP_951031.2 |
Bos taurus (cattle) | FOXK1 | XP_003587905.2 |
Pan troglodytes (chimpanzee) | FOXK1 | XP_003318328.1 |
Gallus gallus (chicken) | FOXK1 | XP_414784.3 |
Rattus norvegicus (Norway rat) | Foxk1 | NP_001032296.2 |
Danio rerio (zebrafish) | foxk1 | NP_956196.1 |
Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs.
Bowman CJ, Ayer DE, Dynlacht BD
Nature cell biology16(12)1202-14(2014 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Foxk1 and Foxk2 are identified as transcriptional repressors of autophagy in muscle cells and fibroblasts.
Title: Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs.
in the developing eyes, Foxk1 protein is localized in bipolar, amacrine and ganglion cells with an onset of Foxk1 expression from E15 onwards; expression pattern during development suggests that Foxk1 may have an important role in retinal cells
Title: The transcription factor Foxk1 is expressed in developing and adult mouse neuroretina.
Foxk1 promotes muscle progenitor cell proliferation by repressing Foxo4 transcriptional activity and inhibits myogenic differentiation by repressing Mef2 activity.
Title: Foxk1 promotes cell proliferation and represses myogenic differentiation by regulating Foxo4 and Mef2.
the transcriptional repression of Foxk1 is dependent on the Sin3-Sds3 repression complex, and knockdown of Sds3 results in cell-cycle arrest.
Title: Foxk1 recruits the Sds3 complex and represses gene expression in myogenic progenitors.
Foxk1 interacts with Sin3 through the N-terminal sin3 interacting domain
Title: Sin3 interacts with Foxk1 and regulates myogenic progenitors.
The following Foxk1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Foxk1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu36283 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504654.2 | |
Accession Version | XM_006504654.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1650bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | forkhead box protein K1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006504654.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTGAGAT GCACCTTCCG GTTCCCGAGC ACGGCCATCA AGATCCAGTT CACATCGCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504717.1 |
CDS | 16..1665 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504654.2 |
1 | ATGCTGAGAT GCACCTTCCG GTTCCCGAGC ACGGCCATCA AGATCCAGTT CACATCGCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09331 | |
Clone ID Related Accession (Same CDS sequence) | NM_199068.2 | |
Accession Version | NM_199068.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2160bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-01 | |
Organism | Mus musculus(house mouse) | |
Product | forkhead box protein K1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB646926.1, AK147375.1, CB249706.1 and BE690639.1. On Nov 18, 2005 this sequence version replaced NM_199068.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK147375.1, BC060238.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCGAAG TCGGCGAGGA CAGCGGCGCC CGCGCCCTGC TGGCGCTGCG CTCGGCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_951031.2 |
CDS | 28..2187 |
Translation |
Target ORF information:
Target ORF information:
|
NM_199068.2 |
1 | ATGGCCGAAG TCGGCGAGGA CAGCGGCGCC CGCGCCCTGC TGGCGCTGCG CTCGGCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs. |