Ndp cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ndp
Entrez Gene ID	17986
Full Name	Norrie disease (pseudoglioma) (human)
Synonyms	ND,Ndph
General protein information	Preferred Names Norrie disease (pseudoglioma) (human) Names norrin norrie disease protein homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X A1.2\|X 12.07 cM
Summary	This gene encodes a secreted protein that acts a ligand for multiple different receptors and participates in both Wnt and Wnt-independant signalling. Its activity is important in vascular development of the eye and inner ear. Mutation of the related gene in humans causes Norrie syndrome. [provided by RefSeq, May 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_010883.3	NP_035013.1	norrin precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	NDP	XP_001139783.1
Bos taurus (cattle)	NDP	NP_001039555.1
	NDP	XP_002806251.1
Canis lupus familiaris (dog)	NDP	XP_855261.1
Gallus gallus (chicken)	NDP	NP_001265015.1
Danio rerio (zebrafish)	LOC100003793	XP_001338820.2
Homo sapiens (human)	NDP	NP_000257.1
Mus musculus (house mouse)	Ndp	NP_035013.1
Xenopus tropicalis (tropical clawed frog)	ndp	XP_002932837.1

Gene Ontology

The following Ndp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ndp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu07092	NM_010883.3 Latest version!	Mus musculus Norrie disease (pseudoglioma) (human) (Ndp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ndp ( NM_010883.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035013.1 Mus musculus Norrie disease (pseudoglioma) (human) (Ndp), mRNA.

Price & Availability↑

CloneID	OMu07092
Clone ID Related Accession (Same CDS sequence)	NM_010883.3
Accession Version	NM_010883.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-16
Organism	Mus musculus(house mouse)
Product	norrin precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CJ062577.1 and BC090623.1. On May 9, 2015 this sequence version replaced NM_010883.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC090623.1, X92397.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGAAATC ATGTACTAGC TGCATCCATT TCTATGCTCT CCCTGCTGGC CATAATGGGA 
GATACAGACA GCAAAACAGA CAGTTCATTT CTGATGGACT CTCAACGCTG CATGAGACAC 
CATTATGTCG ATTCTATCAG TCACCCACTG TACAAATGTA GCTCAAAGAT GGTGCTCCTG 
GCCAGATGTG AGGGGCACTG CAGCCAGGCA TCACGCTCTG AGCCCTTGGT GTCCTTCAGC 
ACTGTCCTCA AGCAACCTTT CCGTTCCTCC TGTCACTGCT GCCGACCCCA GACTTCCAAG 
CTGAAGGCTC TGCGTCTGCG CTGCTCAGGG GGCATGCGAC TTACTGCCAC TTACCGGTAC 
ATCCTCTCCT GTCACTGTGA GGAATGCAGC TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035013.1
CDS	596..991
Translation	MRNHVLAASISMLSLLAIMGDTDSKTDSSFLMDSQRCMRHHYVDSISHPLYKCSSKMVLLARCEGHCSQASRSEPLVSFSTVLKQPFRSSCHCCRPQTSKLKALRLRCSGGMRLTATYRYILSCHCEECSS

Target ORF information:

RefSeq Version	NM_010883.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus Norrie disease (pseudoglioma) (human) (Ndp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010883.3

ORF Insert Sequence:

ATGAGAAATC ATGTACTAGC TGCATCCATT TCTATGCTCT CCCTGCTGGC CATAATGGGA 
GATACAGACA GCAAAACAGA CAGTTCATTT CTGATGGACT CTCAACGCTG CATGAGACAC 
CATTATGTCG ATTCTATCAG TCACCCACTG TACAAATGTA GCTCAAAGAT GGTGCTCCTG 
GCCAGATGTG AGGGGCACTG CAGCCAGGCA TCACGCTCTG AGCCCTTGGT GTCCTTCAGC 
ACTGTCCTCA AGCAACCTTT CCGTTCCTCC TGTCACTGCT GCCGACCCCA GACTTCCAAG 
CTGAAGGCTC TGCGTCTGCG CTGCTCAGGG GGCATGCGAC TTACTGCCAC TTACCGGTAC 
ATCCTCTCCT GTCACTGTGA GGAATGCAGC TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.