Gene Symbol | Nucb1 |
Entrez Gene ID | 18220 |
Full Name | nucleobindin 1 |
Synonyms | B230337F23Rik,C77483,Calnuc,MTEST82,Nucb |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Nucb1 cDNA ORF clone
gRNAs
Gene Symbol | Nucb1 |
Entrez Gene ID | 18220 |
Full Name | nucleobindin 1 |
Synonyms | B230337F23Rik,C77483,Calnuc,MTEST82,Nucb |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006540696.1 | XP_006540759.1 | nucleobindin-1 isoform X1 |
NM_008749.2 | NP_032775.1 | nucleobindin-1 isoform 2 precursor |
XM_017322024.1 | XP_017177513.1 | nucleobindin-1 isoform X1 |
XM_006540696.2 | XP_006540759.1 | nucleobindin-1 isoform X1 |
XM_006540696.3 | XP_006540759.1 | nucleobindin-1 isoform X1 |
XM_017322024.2 | XP_017177513.1 | nucleobindin-1 isoform X1 |
NM_001163662.1 | NP_001157134.1 | nucleobindin-1 isoform 1 precursor |
Homo sapiens (human) | NUCB1 | NP_006175.2 |
Canis lupus familiaris (dog) | NUCB1 | XP_541506.2 |
Danio rerio (zebrafish) | nucb1 | NP_001038928.1 |
Xenopus tropicalis (tropical clawed frog) | nucb1 | NP_998854.1 |
Mus musculus (house mouse) | Nucb1 | NP_001157134.1 |
Rattus norvegicus (Norway rat) | Nucb1 | NP_445915.1 |
Pan troglodytes (chimpanzee) | NUCB1 | XP_512807.3 |
Bos taurus (cattle) | NUCB1 | NP_001068667.1 |
Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles.
Siletti K, Tarchini B, Hudspeth AJ
Proceedings of the National Academy of Sciences of the United States of America114(52)E11170-E11179(2017 Dec)
CHIP mediates down-regulation of nucleobindin-1 in preosteoblast cell line models.
Xue F, Wu Y, Zhao X, Zhao T, Meng Y, Zhao Z, Guo J, Chen W
Cellular signalling28(8)1058-65(2016 08)
Expression of nucleobindin 1 (NUCB1) in pancreatic islets and other endocrine tissues.
Williams P, Tulke S, Ilegems E, Berggren PO, Broberger C
Cell and tissue research358(2)331-42(2014 Nov)
Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.
Lee J, Xu Y, Chen Y, Sprung R, Kim SC, Xie S, Zhao Y
Molecular & cellular proteomics : MCP6(4)669-76(2007 Apr)
Calnuc binds to Alzheimer's beta-amyloid precursor protein and affects its biogenesis.
Lin P, Li F, Zhang YW, Huang H, Tong G, Farquhar MG, Xu H
Journal of neurochemistry100(6)1505-14(2007 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The chaperone protein Hsp70 was found to be important for CHIP and NUCB1 interaction as well as CHIP-mediated NUCB1 down-regulation.
Title: CHIP mediates down-regulation of nucleobindin-1 in preosteoblast cell line models.
the expression and distribution of NUCB1 in tissues and cells of the mouse endocrine system, was examined.
Title: Expression of nucleobindin 1 (NUCB1) in pancreatic islets and other endocrine tissues.
This protein is stored and processed in the Golgi and secreted by the constitutive-like pathway in AtT20 cells.
Title: Calnuc, an EF-hand Ca(2+)-binding protein, is stored and processed in the Golgi and secreted by the constitutive-like pathway in AtT20 cells.
The following Nucb1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nucb1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu02699 | |
Clone ID Related Accession (Same CDS sequence) | NM_008749.2 | |
Accession Version | NM_008749.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1368bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | nucleobindin-1 isoform 2 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC151602.4, AK160981.1 and AK140710.1. On Jul 28, 2009 this sequence version replaced NM_008749.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. This results in a shorter protein (isoform 2) compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M96823.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164143 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_032775.1 |
CDS | 97..1464 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09293 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540696.1 , XM_017322024.1 , XM_006540696.2 , XM_006540696.3 , XM_017322024.2 , NM_001163662.1 | |
Accession Version | NM_001163662.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | nucleobindin-1 isoform 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC151602.4, AK160981.1 and AK140710.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK140710.1, AK045087.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164143 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001157134.1 |
CDS | 97..1476 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09293 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540696.1 , XM_017322024.1 , XM_006540696.2 , XM_006540696.3 , XM_017322024.2 , NM_001163662.1 | |
Accession Version | XM_006540696.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-08 | |
Organism | Mus musculus(House mouse) | |
Product | nucleobindin-1 isoform X1 | |
Comment |
1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540759.1 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09293 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540696.1 , XM_017322024.1 , XM_006540696.2 , XM_006540696.3 , XM_017322024.2 , NM_001163662.1 | |
Accession Version | XM_017322024.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | nucleobindin-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017177513.1 |
CDS | 253..1632 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09293 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540696.1 , XM_017322024.1 , XM_006540696.2 , XM_006540696.3 , XM_017322024.2 , NM_001163662.1 | |
Accession Version | XM_006540696.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | nucleobindin-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006540696.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540759.1 |
CDS | 104..1483 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09293 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540696.1 , XM_017322024.1 , XM_006540696.2 , XM_006540696.3 , XM_017322024.2 , NM_001163662.1 | |
Accession Version | XM_006540696.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | nucleobindin-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006540696.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540759.1 |
CDS | 104..1483 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09293 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540696.1 , XM_017322024.1 , XM_006540696.2 , XM_006540696.3 , XM_017322024.2 , NM_001163662.1 | |
Accession Version | XM_017322024.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | nucleobindin-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017322024.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017177513.1 |
CDS | 253..1632 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCTACCT CGGTGCCCCG CGGGGCCCCT TTTCTTCTCC TACCACCTCT ACTGATGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles. |
CHIP mediates down-regulation of nucleobindin-1 in preosteoblast cell line models. |
Expression of nucleobindin 1 (NUCB1) in pancreatic islets and other endocrine tissues. |
Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS. |
Calnuc binds to Alzheimer's beta-amyloid precursor protein and affects its biogenesis. |