Gene Symbol | Odc1 |
Entrez Gene ID | 18263 |
Full Name | ornithine decarboxylase, structural 1 |
Synonyms | ODC |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Odc1 cDNA ORF clone
gRNAs
Gene Symbol | Odc1 |
Entrez Gene ID | 18263 |
Full Name | ornithine decarboxylase, structural 1 |
Synonyms | ODC |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017314990.1 | XP_017170479.1 | ornithine decarboxylase isoform X1 |
XM_017314990.2 | XP_017170479.1 | ornithine decarboxylase isoform X1 |
NM_013614.2 | NP_038642.2 | ornithine decarboxylase |
Canis lupus familiaris (dog) | ODC1 | XP_856711.1 |
Rattus norvegicus (Norway rat) | Odc1 | NP_036747.1 |
Caenorhabditis elegans (roundworm) | odc-1 | NP_504752.1 |
Schizosaccharomyces pombe (fission yeast) | spe1 | NP_594665.1 |
Oryza sativa (rice) | Os04g0136500 | NP_001052100.2 |
Gallus gallus (chicken) | ODC1 | NP_001161238.1 |
Drosophila melanogaster (fruit fly) | Odc2 | NP_477053.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_02441 | XP_003709230.1 |
Xenopus tropicalis (tropical clawed frog) | odc1 | NP_001005441.1 |
Homo sapiens (human) | ODC1 | NP_002530.1 |
Pan troglodytes (chimpanzee) | ODC1 | XP_001157520.1 |
LOC694559 | XP_001084503.1 | |
Drosophila melanogaster (fruit fly) | Odc1 | NP_477052.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP011805 | XP_320710.4 |
Kluyveromyces lactis | KLLA0B02673g | XP_451651.1 |
Eremothecium gossypii | AGOS_AER087C | NP_984947.2 |
Oryza sativa (rice) | Os09g0543400 | NP_001063827.2 |
Bos taurus (cattle) | ODC1 | NP_776555.1 |
Mus musculus (house mouse) | Odc1 | NP_038642.2 |
Saccharomyces cerevisiae (baker's yeast) | SPE1 | NP_012737.1 |
Neurospora crassa | NCU01271 | XP_960749.1 |
Danio rerio (zebrafish) | odc1 | NP_571876.1 |
Inhibition of polyamine synthesis causes entry of the mouse blastocyst into embryonic diapause.
Fenelon JC, Murphy BD
Biology of reproduction97(1)119-132(2017 Jul)
Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications.
Hardbower DM, Asim M, Luis PB, Singh K, Barry DP, Yang C, Steeves MA, Cleveland JL, Schneider C, Piazuelo MB, Gobert AP, Wilson KT
Proceedings of the National Academy of Sciences of the United States of America114(5)E751-E760(2017 Jan)
Ornithine Decarboxylase Is Sufficient for Prostate Tumorigenesis via Androgen Receptor Signaling.
Shukla-Dave A, Castillo-Martin M, Chen M, Lobo J, Gladoun N, Collazo-Lorduy A, Khan FM, Ponomarev V, Yi Z, Zhang W, Pandolfi PP, Hricak H, Cordon-Cardo C
The American journal of pathology186(12)3131-3145(2016 Dec)
Destabilization of the ornithine decarboxylase mRNA transcript by the RNA-binding protein tristetraprolin.
Nowotarski SL, Origanti S, Sass-Kuhn S, Shantz LM
Amino acids48(10)2303-11(2016 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Ornithine decarboxylase (ODC) plays a key role in prostate tumorigenesis and that the polyamine pathway is altered as early as high-grade prostate intraepithelial neoplasia (HGPIN).
Title: Ornithine Decarboxylase Is Sufficient for Prostate Tumorigenesis via Androgen Receptor Signaling.
these data support the hypothesis that TTP plays a role in the post-transcriptional regulation of the ODC mRNA transcript.
Title: Destabilization of the ornithine decarboxylase mRNA transcript by the RNA-binding protein tristetraprolin.
the Myc-ODC axis plays a critical role in the cellular transformation induced by myeloproliferative neoplasm-associated JAK2 V617F mutant
Title: Critical roles of Myc-ODC axis in the cellular transformation induced by myeloproliferative neoplasm-associated JAK2 V617F mutant.
Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.
Title: Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.
Androgens act via the AR to upregulate Odc1 in skeletal muscle myoblasts, and Odc1 promotes myoblast proliferation and delays differentiation.
Title: Ornithine decarboxylase is upregulated by the androgen receptor in skeletal muscle and regulates myoblast proliferation.
The following Odc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Odc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu09684 | |
Clone ID Related Accession (Same CDS sequence) | XM_017314990.1 , XM_017314990.2 , NM_013614.2 | |
Accession Version | NM_013614.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Mus musculus(house mouse) | |
Product | ornithine decarboxylase | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC163651.2. On Mar 15, 2007 this sequence version replaced NM_013614.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK077679.1, AK150283.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGCAGCT TTACTAAGGA CGAGTTTGAC TGCCACATCC TTGATGAAGG CTTTACTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_038642.2 |
CDS | 411..1796 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAGCAGCT TTACTAAGGA CGAGTTTGAC TGCCACATCC TTGATGAAGG CTTTACTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09684 | |
Clone ID Related Accession (Same CDS sequence) | XM_017314990.1 , XM_017314990.2 , NM_013614.2 | |
Accession Version | XM_017314990.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | ornithine decarboxylase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGCAGCT TTACTAAGGA CGAGTTTGAC TGCCACATCC TTGATGAAGG CTTTACTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017170479.1 |
CDS | 414..1799 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAGCAGCT TTACTAAGGA CGAGTTTGAC TGCCACATCC TTGATGAAGG CTTTACTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09684 | |
Clone ID Related Accession (Same CDS sequence) | XM_017314990.1 , XM_017314990.2 , NM_013614.2 | |
Accession Version | XM_017314990.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | ornithine decarboxylase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017314990.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGCAGCT TTACTAAGGA CGAGTTTGAC TGCCACATCC TTGATGAAGG CTTTACTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017170479.1 |
CDS | 473..1858 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAGCAGCT TTACTAAGGA CGAGTTTGAC TGCCACATCC TTGATGAAGG CTTTACTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Inhibition of polyamine synthesis causes entry of the mouse blastocyst into embryonic diapause. |
Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications. |
Ornithine Decarboxylase Is Sufficient for Prostate Tumorigenesis via Androgen Receptor Signaling. |
Destabilization of the ornithine decarboxylase mRNA transcript by the RNA-binding protein tristetraprolin. |