Gene Symbol | Orc1 |
Entrez Gene ID | 18392 |
Full Name | origin recognition complex, subunit 1 |
Synonyms | AA545195,MmORC1,Orc1l |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Orc1 cDNA ORF clone
Gene Symbol | Orc1 |
Entrez Gene ID | 18392 |
Full Name | origin recognition complex, subunit 1 |
Synonyms | AA545195,MmORC1,Orc1l |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_011240469.2 | XP_011238771.1 | origin recognition complex subunit 1 isoform X1 |
XM_011240469.3 | XP_011238771.1 | origin recognition complex subunit 1 isoform X2 |
NM_011015.2 | NP_035145.2 | origin recognition complex subunit 1 |
XM_030253310.1 | XP_030109170.1 | origin recognition complex subunit 1 isoform X1 |
Homo sapiens (human) | ORC1 | NP_001177747.1 |
Pan troglodytes (chimpanzee) | ORC1 | XP_513408.2 |
ORC1 | XP_001111614.1 | |
Canis lupus familiaris (dog) | ORC1 | XP_005629058.1 |
Bos taurus (cattle) | ORC1 | NP_001014918.1 |
Rattus norvegicus (Norway rat) | Orc1 | NP_808792.1 |
Gallus gallus (chicken) | ORC1 | NP_001026457.1 |
Danio rerio (zebrafish) | orc1 | NP_956227.1 |
Xenopus tropicalis (tropical clawed frog) | orc1 | NP_001039194.1 |
Mus musculus (house mouse) | Orc1 | NP_035145.2 |
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Sundberg JP, Dadras SS, Silva KA, Kennedy VE, Garland G, Murray SA, Sundberg BA, Schofield PN, Pratt CH
PloS one12(7)e0180682(2017)
High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)
Novel splicing variant of mouse Orc1 is deficient in nuclear translocation and resistant for proteasome-mediated degradation.
Miyake Y, Mizuno T, Yanagi K, Hanaoka F
The Journal of biological chemistry280(13)12643-52(2005 Apr)
Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells.
Kneissl M, P?tter V, Szalay AA, Grummt F
Journal of molecular biology327(1)111-28(2003 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
mouse Orc1, Orc2, and Orc3 each exist in two alternative-splicing variants and naturally occurring Orc1B lacks a functional domain that is essential for nuclear translocation and proteasome-dependent degradation
Title: Novel splicing variant of mouse Orc1 is deficient in nuclear translocation and resistant for proteasome-mediated degradation.
The following Orc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Orc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu07299 | |
Clone ID Related Accession (Same CDS sequence) | NM_011015.2 | |
Accession Version | NM_011015.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2523bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Mus musculus(house mouse) | |
Product | origin recognition complex subunit 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK164035.1, AK141741.1 and AJ003133.1. On Oct 20, 2007 this sequence version replaced NM_011015.1. ##Evidence-Data-START## Transcript exon combination :: AJ003133.1, AK164035.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCATCCT ACCTCACAAG GCAGAAGACC AGACAAACTT TCTCATGGGT TGGCAGGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_035145.2 |
CDS | 134..2656 |
Translation |
Target ORF information:
Target ORF information:
|
NM_011015.2 |
1 | ATGCCATCCT ACCTCACAAG GCAGAAGACC AGACAAACTT TCTCATGGGT TGGCAGGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu68366 | |
Clone ID Related Accession (Same CDS sequence) | XM_011240469.2 , XM_011240469.3 | |
Accession Version | XM_011240469.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2427bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | origin recognition complex subunit 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011240469.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTGTTCA ACTTTCAGCC CATCAGACCA TGCCATCCTA CCTCACAAGG CAGAAGACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011238771.1 |
CDS | 101..2527 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011240469.2 |
1 | ATGTTGTTCA ACTTTCAGCC CATCAGACCA TGCCATCCTA CCTCACAAGG CAGAAGACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu68366 | |
Clone ID Related Accession (Same CDS sequence) | XM_011240469.2 , XM_011240469.3 | |
Accession Version | XM_011240469.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2427bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | origin recognition complex subunit 1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011240469.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTGTTCA ACTTTCAGCC CATCAGACCA TGCCATCCTA CCTCACAAGG CAGAAGACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011238771.1 |
CDS | 16..2442 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011240469.3 |
1 | ATGTTGTTCA ACTTTCAGCC CATCAGACCA TGCCATCCTA CCTCACAAGG CAGAAGACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu88462 | |
Clone ID Related Accession (Same CDS sequence) | XM_030253310.1 | |
Accession Version | XM_030253310.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2451bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | origin recognition complex subunit 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTGAACT CCATTAAGGC AGGAACTGAC TGTATCTTAC AGCCCATCAG ACCATGCCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030109170.1 |
CDS | 3856..6306 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030253310.1 |
1 | ATGCTGAACT CCATTAAGGC AGGAACTGAC TGTATCTTAC AGCCCATCAG ACCATGCCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. |
High-throughput discovery of novel developmental phenotypes. |
Novel splicing variant of mouse Orc1 is deficient in nuclear translocation and resistant for proteasome-mediated degradation. |
Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. |