Pex7 cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Pex7 |
| Entrez Gene ID | 18634 |
| Full Name | peroxisomal biogenesis factor 7 |
| Synonyms | MmPEX7 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_001161825.1 | NP_001155297.1 | peroxisomal biogenesis factor 7 isoform 2 |
| NM_008822.2 | NP_032848.1 | peroxisomal biogenesis factor 7 isoform 1 |
| PEX7 | XP_001097630.1 | |
| Canis lupus familiaris (dog) | PEX7 | XP_541117.2 |
| Mus musculus (house mouse) | Pex7 | NP_032848.1 |
| Oryza sativa (rice) | Os02g0245100 | NP_001046419.1 |
| Pan troglodytes (chimpanzee) | PEX7 | XP_518763.2 |
| Rattus norvegicus (Norway rat) | Pex7 | NP_001029319.1 |
| Danio rerio (zebrafish) | pex7 | NP_001013550.1 |
| Xenopus tropicalis (tropical clawed frog) | pex7 | NP_001015954.1 |
| Gallus gallus (chicken) | PEX7 | NP_001264638.1 |
| Bos taurus (cattle) | PEX7 | NP_001070358.1 |
| Drosophila melanogaster (fruit fly) | Pex7 | NP_001137914.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP006264 | XP_001688840.1 |
| Homo sapiens (human) | PEX7 | NP_000279.1 |
| Arabidopsis thaliana (thale cress) | PEX7 | NP_174220.1 |
Related articles in PubMed
Plasmalogen phospholipids protect internodal myelin from oxidative damage.
Luoma AM, Kuo F, Cakici O, Crowther MN, Denninger AR, Avila RL, Brites P, Kirschner DA
Free radical biology & medicine84296-310(2015 Jul)
A PEX7-centered perspective on the peroxisomal targeting signal type 2-mediated protein import pathway.
Rodrigues TA, Alencastre IS, Francisco T, Brites P, Fransen M, Grou CP, Azevedo JE
Molecular and cellular biology34(15)2917-28(2014 Aug)
Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination.
da Silva TF, Eira J, Lopes AT, Malheiro AR, Sousa V, Luoma A, Avila RL, Wanders RJ, Just WW, Kirschner DA, Sousa MM, Brites P
The Journal of clinical investigation124(6)2560-70(2014 Jun)
Peroxisomes: a nexus for lipid metabolism and cellular signaling.
Lodhi IJ, Semenkovich CF
Cell metabolism19(3)380-92(2014 Mar)
PEX7 and EBP50 target iNOS to the peroxisome in hepatocytes.
Loughran PA, Stolz DB, Barrick SR, Wheeler DS, Friedman PA, Rachubinski RA, Watkins SC, Billiar TR
Nitric oxide : biology and chemistry319-19(2013 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
siRNA knockdown of PEX7 reduced iNOS colocalization with the peroxisomal protein PMP70. Proteomic studies using MALDI-MS identified iNOS association with the 50-kD ezrin binding PDZ protein (EBP50).
Title: PEX7 and EBP50 target iNOS to the peroxisome in hepatocytes.
Our data established that peroxisomal processing protease Tysnd1 is necessary to mediate the physiological functions of PTS2-containing substrates.
Title: Tysnd1 deficiency in mice interferes with the peroxisomal localization of PTS2 enzymes, causing lipid metabolic abnormalities and male infertility.
Mutations in the Pex7 gene cause impaired neuronal migration and endochondral ossification.
Title: Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata.
The following Pex7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pex7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu08315 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001161825.1 | |
| Accession Version | NM_001161825.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-03 | |
| Organism | Mus musculus(house mouse) | |
| Product | peroxisomal biogenesis factor 7 isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DV660555.1, BC145300.1 and AC171277.9. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC145300.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGAGCGCGG CGCGGACGCT GCGGGTGCCC GGCCGCCACG GCTATGCGGC CGAGTTCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001155297.1 |
| CDS | 102..980 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001161825.1 |
ORF Insert Sequence:
1 | ATGAGCGCGG CGCGGACGCT GCGGGTGCCC GGCCGCCACG GCTATGCGGC CGAGTTCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu02852 | |
| Clone ID Related Accession (Same CDS sequence) | NM_008822.2 | |
| Accession Version | NM_008822.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Mus musculus(house mouse) | |
| Product | peroxisomal biogenesis factor 7 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DV660555.1, BC132213.1 and AC171277.9. On Jun 18, 2009 this sequence version replaced NM_008822.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK160195.1, U69171.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164143 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGAGCGCGG CGCGGACGCT GCGGGTGCCC GGCCGCCACG GCTATGCGGC CGAGTTCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_032848.1 |
| CDS | 102..1058 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_008822.2 |
ORF Insert Sequence:
1 | ATGAGCGCGG CGCGGACGCT GCGGGTGCCC GGCCGCCACG GCTATGCGGC CGAGTTCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Plasmalogen phospholipids protect internodal myelin from oxidative damage. |
|
A PEX7-centered perspective on the peroxisomal targeting signal type 2-mediated protein import pathway. |
|
Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination. |
|
Peroxisomes: a nexus for lipid metabolism and cellular signaling. |
|
PEX7 and EBP50 target iNOS to the peroxisome in hepatocytes. |