Rhox6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rhox6
Entrez Gene ID	19202
Full Name	reproductive homeobox 6
Synonyms	AV213605,AW548842,Psx1
General protein information	Preferred Names reproductive homeobox 6 Names reproductive homeobox on X chromosome, 6 placenta specific homeobox 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X\|X A3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_008955.1	NP_032981.1	reproductive homeobox on X chromosome, 6

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Rhox9	NP_076383.1
Mus musculus (house mouse)	Rhox6	NP_032981.1

Gene Ontology
Bibliography

Related articles in PubMed

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

Female bias in Rhox6 and 9 regulation by the histone demethylase KDM6A.
Berletch JB, Deng X, Nguyen DK, Disteche CM
PLoS genetics9(5)e1003489(2013 May)

Regulation of lineage specific DNA hypomethylation in mouse trophectoderm.
Oda M, Oxley D, Dean W, Reik W
PloS one8(6)e68846(2013)

Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation.
Mugford JW, Yee D, Magnuson T
Development (Cambridge, England)139(12)2130-8(2012 Jun)

A possible role of Reproductive Homeobox 6 in primordial germ cell differentiation.
Liu C, Tsai P, Garc?a AM, Logeman B, Tanaka TS
The International journal of developmental biology55(10-12)909-16(2011)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We report that two members of the Rhox cluster, Rhox6 and 9, are regulated by de-methylation of histone H3 at lysine 27 by KDM6A
Title: Female bias in Rhox6 and 9 regulation by the histone demethylase KDM6A.

Rhox6 is necessary for determination of the germ cell lineage
Title: A possible role of Reproductive Homeobox 6 in primordial germ cell differentiation.

The following Rhox6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rhox6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18541	NM_008955.1 Latest version!	Mus musculus reproductive homeobox 6 (Rhox6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rhox6 ( NM_008955.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032981.1 Mus musculus reproductive homeobox 6 (Rhox6), mRNA.

Price & Availability↑

CloneID	OMu18541
Clone ID Related Accession (Same CDS sequence)	NM_008955.1
Accession Version	NM_008955.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-08-10
Organism	Mus musculus(house mouse)
Product	reproductive homeobox on X chromosome, 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF017453.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF017453.1, DQ058643.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849385, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAACTC CTCAAGACAG CCGCCAAAGC ATCCAAAAGC CTCCGAGTCC GGCAGCCGAG 
GAGGACAAGG AAGAACAGCC TGGTGGGAAT GCAGTGGTCT CCGGGGCTCC AGAGGAAAGA 
ATAGACAAGA AAGAGCTTGT ACTGAACTGG CTCGCTCAGG GTGAGTTTGA TCAGGGCGAA 
GGCGCTCAGG GCGAGGTTGC TGGAGGTGAG CAGGCTCAAG AAGAGCCTGC TCCATTGAGT 
CCAGCTCAGG AAGCCACTGG AGGAGAAGAG GAGGGAGAAA ACAAGGAAGG AGAAATGGAA 
GGAAGACATG CTGGTGATGG TGCTTCTAGC TCCGAGGATG ACAGCATCCT GGAAGAAGGC 
GGCGAAAACA TAGATCAACA GCCGCCTCAG CAAGAGGCAG CCAGTCCTGA TAGCATCAGA 
AACCCACATG TTCTGAATAG GCTGGCTCAA CTGCGGTACA GACGCACCAG GTTCACCCAC 
TCTCAGCTGC ATGACCTGGA GCGCCTTTTC CAAGAGACTC GCTACCCCAG CTTGCGAGCA 
AGGAGGGATC TTGCACGATG GATGGGTGTG GATGAATGTG ATGTGCAGAA TTGGTTTCGG 
ATGAGGAGAG CCCTTTTCCA GAGAAACAGG AGAGTGCTGA TGTTCTGCGA ACTGCCGCCT 
CTTCCCCAGA GCGACTCTCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032981.1
CDS	44..727
Translation	METPQDSRQSIQKPPSPAAEEDKEEQPGGNAVVSGAPEERIDKKELVLNWLAQGEFDQGEGAQGEVAGGEQAQEEPAPLSPAQEATGGEEEGENKEGEMEGRHAGDGASSSEDDSILEEGGENIDQQPPQQEAASPDSIRNPHVLNRLAQLRYRRTRFTHSQLHDLERLFQETRYPSLRARRDLARWMGVDECDVQNWFRMRRALFQRNRRVLMFCELPPLPQSDSP

Target ORF information:

RefSeq Version	NM_008955.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus reproductive homeobox 6 (Rhox6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008955.1

ORF Insert Sequence:

ATGGAAACTC CTCAAGACAG CCGCCAAAGC ATCCAAAAGC CTCCGAGTCC GGCAGCCGAG 
GAGGACAAGG AAGAACAGCC TGGTGGGAAT GCAGTGGTCT CCGGGGCTCC AGAGGAAAGA 
ATAGACAAGA AAGAGCTTGT ACTGAACTGG CTCGCTCAGG GTGAGTTTGA TCAGGGCGAA 
GGCGCTCAGG GCGAGGTTGC TGGAGGTGAG CAGGCTCAAG AAGAGCCTGC TCCATTGAGT 
CCAGCTCAGG AAGCCACTGG AGGAGAAGAG GAGGGAGAAA ACAAGGAAGG AGAAATGGAA 
GGAAGACATG CTGGTGATGG TGCTTCTAGC TCCGAGGATG ACAGCATCCT GGAAGAAGGC 
GGCGAAAACA TAGATCAACA GCCGCCTCAG CAAGAGGCAG CCAGTCCTGA TAGCATCAGA 
AACCCACATG TTCTGAATAG GCTGGCTCAA CTGCGGTACA GACGCACCAG GTTCACCCAC 
TCTCAGCTGC ATGACCTGGA GCGCCTTTTC CAAGAGACTC GCTACCCCAG CTTGCGAGCA 
AGGAGGGATC TTGCACGATG GATGGGTGTG GATGAATGTG ATGTGCAGAA TTGGTTTCGG 
ATGAGGAGAG CCCTTTTCCA GAGAAACAGG AGAGTGCTGA TGTTCTGCGA ACTGCCGCCT 
CTTCCCCAGA GCGACTCTCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

Female bias in Rhox6 and 9 regulation by the histone demethylase KDM6A.
PLoS genetics9(5)e1003489(2013 May)
Berletch JB,Deng X,Nguyen DK,Disteche CM

Regulation of lineage specific DNA hypomethylation in mouse trophectoderm.
PloS one8(6)e68846(2013)
Oda M,Oxley D,Dean W,Reik W

Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation.
Development (Cambridge, England)139(12)2130-8(2012 Jun)
Mugford JW,Yee D,Magnuson T

A possible role of Reproductive Homeobox 6 in primordial germ cell differentiation.
The International journal of developmental biology55(10-12)909-16(2011)
Liu C,Tsai P,Garc?a AM,Logeman B,Tanaka TS