Gene Symbol | RUVBL2 |
Entrez Gene ID | 20174 |
Full Name | RuvB-like protein 2 |
Synonyms | mp47,p47 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(House mouse) |
Genome |
ORF » Species Summary » Mus musculus » RUVBL2 cDNA ORF clone
gRNAs
Gene Symbol | RUVBL2 |
Entrez Gene ID | 20174 |
Full Name | RuvB-like protein 2 |
Synonyms | mp47,p47 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(House mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_011304.3 | NP_035434.1 | ruvB-like 2 |
XM_006540722.1 | XP_006540785.1 | ruvB-like 2 isoform X1 |
XM_006540723.4 | XP_006540786.1 | ruvB-like 2 isoform X1 |
XM_006540722.2 | XP_006540785.1 | ruvB-like 2 isoform X1 |
XM_006540723.3 | XP_006540786.1 | ruvB-like 2 isoform X1 |
XM_006540723.2 | XP_006540786.1 | ruvB-like 2 isoform X1 |
Homo sapiens (human) | RUVBL2 | NP_006657.1 |
Canis lupus familiaris (dog) | RUVBL2 | XP_533625.2 |
Mus musculus (house mouse) | Ruvbl2 | NP_035434.1 |
Schizosaccharomyces pombe (fission yeast) | rvb2 | NP_595640.1 |
Danio rerio (zebrafish) | ruvbl2 | NP_777285.1 |
Caenorhabditis elegans (roundworm) | ruvb-2 | NP_501067.1 |
Kluyveromyces lactis | KLLA0C15895g | XP_452910.1 |
RUVBL2 | XP_002801376.1 | |
Rattus norvegicus (Norway rat) | Ruvbl2 | NP_001020576.2 |
Eremothecium gossypii | AGOS_AFL142W | NP_985408.2 |
Neurospora crassa | NCU06854 | XP_963328.1 |
Pan troglodytes (chimpanzee) | RUVBL2 | XP_001172052.1 |
Bos taurus (cattle) | RUVBL2 | NP_001033615.1 |
Drosophila melanogaster (fruit fly) | rept | NP_001262040.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP009746 | XP_318830.2 |
Saccharomyces cerevisiae (baker's yeast) | RVB2 | NP_015089.1 |
Arabidopsis thaliana (thale cress) | AT3G49830 | NP_190552.1 |
Oryza sativa (rice) | Os06g0186900 | NP_001057013.2 |
Xenopus tropicalis (tropical clawed frog) | ruvbl2 | NP_001004856.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_03173 | XP_003716817.1 |
Arabidopsis thaliana (thale cress) | AT5G67630 | NP_201564.1 |
RuvB-Like Protein 2 (Ruvbl2) Has a Role in Directing the Neuroectodermal Differentiation of Mouse Embryonic Stem Cells.
Hong S, Jo J, Kim HJ, Lee JE, Shin DH, Lee SG, Baek A, Shim SH, Lee DR
Stem cells and development25(18)1376-85(2016 09)
Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression.
Tarangelo A, Lo N, Teng R, Kim E, Le L, Watson D, Furth EE, Raman P, Ehmer U, Viatour P
Nature communications610028(2015 Dec)
Reptin regulates pluripotency of embryonic stem cells and somatic cell reprogramming through Oct4-dependent mechanism.
Do EK, Cheon HC, Jang IH, Choi EJ, Heo SC, Kang KT, Bae KH, Cho YS, Seo JK, Yoon JH, Lee TG, Kim JH
Stem cells (Dayton, Ohio)32(12)3126-36(2014 Dec)
Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression.
Hosokawa H, Tanaka T, Kato M, Shinoda K, Tohyama H, Hanazawa A, Tamaki Y, Hirahara K, Yagi R, Sakikawa I, Morita A, Nagira M, Poyurovsky MV, Suzuki Y, Motohashi S, Nakayama T
Proceedings of the National Academy of Sciences of the United States of America110(46)18626-31(2013 Nov)
The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.
Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H
PloS one8(10)e75754(2013)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Ruvbl2 has a role in the differentiation of neuroectoderm during early embryogenesis.
Title: RuvB-Like Protein 2 (Ruvbl2) Has a Role in Directing the Neuroectodermal Differentiation of Mouse Embryonic Stem Cells.
accumulating E2f1 progressively recruits a Pontin/Reptin complex to open the chromatin conformation at E2f target genes and amplifies the E2f transcriptional response.
Title: Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression.
Reptin plays a key role in maintaining the pluripotency of embryonic stem cells and in establishing the pluripotency during reprogramming of somatic cells by regulation of Oct4-mediated gene regulation
Title: Reptin regulates pluripotency of embryonic stem cells and somatic cell reprogramming through Oct4-dependent mechanism.
Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression.
Title: Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression.
We demonstrate that leukemogenic activity of MLL-AF9 requires RUVBL2 (RuvB-like 2), an AAA+ ATPase family member that functions in a wide range of cellular processes, including chromatin remodeling and transcriptional regulation.
Title: The AAA+ ATPase RUVBL2 is a critical mediator of MLL-AF9 oncogenesis.
The following RUVBL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RUVBL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu21964 | |
Clone ID Related Accession (Same CDS sequence) | NM_011304.3 , XM_006540722.1 , XM_006540723.4 , XM_006540722.2 , XM_006540723.3 , XM_006540723.2 | |
Accession Version | NM_011304.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1392bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-06 | |
Organism | Mus musculus(house mouse) | |
Product | ruvB-like 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK159112.1. On Apr 6, 2007 this sequence version replaced NM_011304.2. Sequence Note: removed 2 bases from the 5' end that did not align to the reference genome assembly. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK159112.1, AK144156.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164134 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCAACCG TGGCAGCCAC CACCAAAGTC CCTGAGATCC GAGATGTGAC AAGAATCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_035434.1 |
CDS | 202..1593 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAACCG TGGCAGCCAC CACCAAAGTC CCTGAGATCC GAGATGTGAC AAGAATCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21964 | |
Clone ID Related Accession (Same CDS sequence) | NM_011304.3 , XM_006540722.1 , XM_006540723.4 , XM_006540722.2 , XM_006540723.3 , XM_006540723.2 | |
Accession Version | XM_006540722.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1392bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | ruvB-like 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAACCG TGGCAGCCAC CACCAAAGTC CCTGAGATCC GAGATGTGAC AAGAATCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540785.1 |
CDS | 179..1570 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAACCG TGGCAGCCAC CACCAAAGTC CCTGAGATCC GAGATGTGAC AAGAATCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21964 | |
Clone ID Related Accession (Same CDS sequence) | NM_011304.3 , XM_006540722.1 , XM_006540723.4 , XM_006540722.2 , XM_006540723.3 , XM_006540723.2 | |
Accession Version | XM_006540723.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1392bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | ruvB-like 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006540723.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAACCG TGGCAGCCAC CACCAAAGTC CCTGAGATCC GAGATGTGAC AAGAATCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540786.1 |
CDS | 546..1937 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAACCG TGGCAGCCAC CACCAAAGTC CCTGAGATCC GAGATGTGAC AAGAATCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21964 | |
Clone ID Related Accession (Same CDS sequence) | NM_011304.3 , XM_006540722.1 , XM_006540723.4 , XM_006540722.2 , XM_006540723.3 , XM_006540723.2 | |
Accession Version | XM_006540723.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1392bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-08 | |
Organism | Mus musculus(House mouse) | |
Product | ruvB-like 2 isoform X1 | |
Comment |
1 | ATGGCAACCG TGGCAGCCAC CACCAAAGTC CCTGAGATCC GAGATGTGAC AAGAATCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540786.1 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAACCG TGGCAGCCAC CACCAAAGTC CCTGAGATCC GAGATGTGAC AAGAATCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21964 | |
Clone ID Related Accession (Same CDS sequence) | NM_011304.3 , XM_006540722.1 , XM_006540723.4 , XM_006540722.2 , XM_006540723.3 , XM_006540723.2 | |
Accession Version | XM_006540723.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1392bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | ruvB-like 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006540723.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAACCG TGGCAGCCAC CACCAAAGTC CCTGAGATCC GAGATGTGAC AAGAATCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540786.1 |
CDS | 1385..2776 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAACCG TGGCAGCCAC CACCAAAGTC CCTGAGATCC GAGATGTGAC AAGAATCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21964 | |
Clone ID Related Accession (Same CDS sequence) | NM_011304.3 , XM_006540722.1 , XM_006540723.4 , XM_006540722.2 , XM_006540723.3 , XM_006540723.2 | |
Accession Version | XM_006540722.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1392bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | ruvB-like 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006540722.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAACCG TGGCAGCCAC CACCAAAGTC CCTGAGATCC GAGATGTGAC AAGAATCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540785.1 |
CDS | 191..1582 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAACCG TGGCAGCCAC CACCAAAGTC CCTGAGATCC GAGATGTGAC AAGAATCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RuvB-Like Protein 2 (Ruvbl2) Has a Role in Directing the Neuroectodermal Differentiation of Mouse Embryonic Stem Cells. |
Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression. |
Reptin regulates pluripotency of embryonic stem cells and somatic cell reprogramming through Oct4-dependent mechanism. |
Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression. |
The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. |