Gene Symbol | Exoc4 |
Entrez Gene ID | 20336 |
Full Name | exocyst complex component 4 |
Synonyms | C78892,Sec8,Sec8l1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Exoc4 cDNA ORF clone
Gene Symbol | Exoc4 |
Entrez Gene ID | 20336 |
Full Name | exocyst complex component 4 |
Synonyms | C78892,Sec8,Sec8l1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_009148.3 | NP_033174.2 | exocyst complex component 4 isoform 1 |
NM_001347089.2 | NP_001334018.1 | exocyst complex component 4 isoform 2 |
NM_009148.4 | NP_033174.2 | exocyst complex component 4 isoform 1 |
NM_001347089.1 | NP_001334018.1 | exocyst complex component 4 isoform 2 |
XM_011241262.1 | XP_011239564.1 | exocyst complex component 4 isoform X1 |
EXOC4 | XP_001101640.2 | |
Canis lupus familiaris (dog) | EXOC4 | XP_539369.2 |
Mus musculus (house mouse) | Exoc4 | NP_033174.2 |
Rattus norvegicus (Norway rat) | Exoc4 | NP_446327.1 |
Pan troglodytes (chimpanzee) | EXOC4 | XP_001139207.1 |
Drosophila melanogaster (fruit fly) | sec8 | NP_730996.2 |
Xenopus tropicalis (tropical clawed frog) | exoc4 | XP_002931915.2 |
Homo sapiens (human) | EXOC4 | NP_068579.3 |
Gallus gallus (chicken) | EXOC4 | NP_001186249.1 |
Bos taurus (cattle) | EXOC4 | NP_001095677.1 |
Danio rerio (zebrafish) | exoc4 | NP_001025305.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP001694 | XP_321399.5 |
Caenorhabditis elegans (roundworm) | sec-8 | NP_492732.2 |
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Sundberg JP, Dadras SS, Silva KA, Kennedy VE, Garland G, Murray SA, Sundberg BA, Schofield PN, Pratt CH
PloS one12(7)e0180682(2017)
Ascl3 transcription factor marks a distinct progenitor lineage for non-neuronal support cells in the olfactory epithelium.
Weng PL, Vinjamuri M, Ovitt CE
Scientific reports638199(2016 Dec)
CREG1 Interacts with Sec8 to Promote Cardiomyogenic Differentiation and Cell-Cell Adhesion.
Liu J, Qi Y, Li S, Hsu SC, Saadat S, Hsu J, Rahimi SA, Lee LY, Yan C, Tian X, Han Y
Stem cells (Dayton, Ohio)34(11)2648-2660(2016 Nov)
Arl13b and the exocyst interact synergistically in ciliogenesis.
Seixas C, Choi SY, Polgar N, Umberger NL, East MP, Zuo X, Moreiras H, Ghossoub R, Benmerah A, Kahn RA, Fogelgren B, Caspary T, Lipschutz JH, Barral DC
Molecular biology of the cell27(2)308-20(2016 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Insulin stimulates the phosphorylation of the exocyst protein Sec8 in adipocytes.
Title: Insulin stimulates the phosphorylation of the exocyst protein Sec8 in adipocytes.
Interaction of Discs large 1 (Dlg1) with the Sec8 exocyst component promotes membrane addition, whereas with myotubularin-related protein 2 (Mtmr2), negatively regulates membrane formation.
Title: Dlg1, Sec8, and Mtmr2 regulate membrane homeostasis in Schwann cell myelination.
Sec8 controls the directional movement of AMPA receptors towards synapses through PDZ-dependent interactions.
Title: Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane.
the exocyst complex serves to selectively regulate the docking of insulin-containing vesicles at sites of release close to the plasma membrane
Title: Mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis.
SAP102 interacts with the PDZ-binding domain of Sec8, a member of the exocyst complex. Interactions between the two proteins are involved in the delivery of N-methyl-D-aspartate receptors to the cell surface in heterologous cells and neurons.
Title: NMDA receptor trafficking through an interaction between PDZ proteins and the exocyst complex.
The following Exoc4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Exoc4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu68663 | |
Clone ID Related Accession (Same CDS sequence) | NM_001347089.2 , NM_001347089.1 | |
Accession Version | NM_001347089.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1569bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-30 | |
Organism | Mus musculus(house mouse) | |
Product | exocyst complex component 4 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC132453.3 and AC152961.2. On Mar 28, 2018 this sequence version replaced NM_001347089.1. Transcript Variant: This variant (2) lacks several exons and includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK014499.1, AK036507.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001334018.1 |
CDS | 26..1594 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001347089.2 |
1 | ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu68663 | |
Clone ID Related Accession (Same CDS sequence) | NM_001347089.2 , NM_001347089.1 | |
Accession Version | NM_001347089.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1569bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-12-09 | |
Organism | Mus musculus(house mouse) | |
Product | exocyst complex component 4 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC132453.3 and AC152961.2. On Nov 15, 2016 this sequence version replaced XM_011241263.1. Transcript Variant: This variant (2) lacks several exons and includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK014499.1, AK036507.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001334018.1 |
CDS | 64..1632 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001347089.1 |
1 | ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu03609 | |
Clone ID Related Accession (Same CDS sequence) | NM_009148.3 , NM_009148.4 | |
Accession Version | NM_009148.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2928bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-12-09 | |
Organism | Mus musculus(house mouse) | |
Product | exocyst complex component 4 isoform 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC132453.3, AC152961.2, AC141927.3, AC154020.3 and AC155915.2. On Nov 17, 2006 this sequence version replaced NM_009148.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC034644.1, SRR1660819.160998.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_033174.2 |
CDS | 4..2931 |
Translation |
Target ORF information:
Target ORF information:
|
NM_009148.3 |
1 | ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu03609 | |
Clone ID Related Accession (Same CDS sequence) | NM_009148.3 , NM_009148.4 | |
Accession Version | NM_009148.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2928bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-30 | |
Organism | Mus musculus(house mouse) | |
Product | exocyst complex component 4 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC132453.3, AC152961.2, AC141927.3, AC154020.3 and AC155915.2. On Mar 19, 2018 this sequence version replaced NM_009148.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660819.160998.1, BC034644.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_033174.2 |
CDS | 26..2953 |
Translation |
Target ORF information:
Target ORF information:
|
NM_009148.4 |
1 | ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu68662 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241262.1 | |
Accession Version | XM_011241262.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2223bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | exocyst complex component 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011239564.1 |
CDS | 64..2286 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011241262.1 |
1 | ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. |
Ascl3 transcription factor marks a distinct progenitor lineage for non-neuronal support cells in the olfactory epithelium. |
CREG1 Interacts with Sec8 to Promote Cardiomyogenic Differentiation and Cell-Cell Adhesion. |
Arl13b and the exocyst interact synergistically in ciliogenesis. |