Gene Symbol | Swap70 |
Entrez Gene ID | 20947 |
Full Name | SWA-70 protein |
Synonyms | 70kDa,AV235546 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Swap70 cDNA ORF clone
Gene Symbol | Swap70 |
Entrez Gene ID | 20947 |
Full Name | SWA-70 protein |
Synonyms | 70kDa,AV235546 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_009302.3 | NP_033328.3 | switch-associated protein 70 |
XM_017322086.1 | XP_017177575.1 | switch-associated protein 70 isoform X1 |
Homo sapiens (human) | SWAP70 | NP_055870.2 |
Bos taurus (cattle) | SWAP70 | NP_001073766.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012332 | XP_001238272.2 |
Pan troglodytes (chimpanzee) | SWAP70 | XP_508279.2 |
Canis lupus familiaris (dog) | SWAP70 | XP_542503.3 |
Mus musculus (house mouse) | Swap70 | NP_033328.3 |
SWAP70 | NP_001165885.1 | |
Gallus gallus (chicken) | SWAP70 | NP_001026351.1 |
Rattus norvegicus (Norway rat) | Swap70 | NP_001099758.1 |
Danio rerio (zebrafish) | swap70b | NP_001038451.1 |
Xenopus tropicalis (tropical clawed frog) | swap70 | XP_002936790.2 |
Regulation of systemic autoimmunity and CD11c
Manni M, Ricker E, Pernis AB
Cellular immunology32146-51(2017 Nov)
The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity.
Yi W, Gupta S, Ricker E, Manni M, Jessberger R, Chinenov Y, Molina H, Pernis AB
Nature communications8(1)254(2017 08)
Tolerogenic versus Immunogenic Lipidomic Profiles of CD11c
Oca?a-Morgner C, Sales S, Rothe M, Shevchenko A, Jessberger R
Journal of immunology (Baltimore, Md. : 1950)198(11)4360-4372(2017 Jun)
SWEF Proteins Distinctly Control Maintenance and Differentiation of Hematopoietic Stem Cells.
Ripich T, Chac?n-Mart?nez CA, Fischer L, Pernis A, Kiessling N, Garbe AI, Jessberger R
PloS one11(8)e0161060(2016)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Studies indicate that the autoimmune phenotype in DEF6 and SWAP-70 knock-out (DKO) mice is characterized by the accumulation of B cell subset that expresses high levels of CD11c and T-bet (ABCs).
Title: Regulation of systemic autoimmunity and CD11c
findings show characteristic changes in the lipidome of CD11c+ immune cells upon their activation, and reveal an important role of SWAP-70 in the selective generation and localization of ceramides
Title: Tolerogenic versus Immunogenic Lipidomic Profiles of CD11c
SWAP-70 is not a typical oncogene, but is required for spontaneous transformation of mouse embryo fibroblasts.
Title: SWAP-70 contributes to spontaneous transformation of mouse embryo fibroblasts.
DEF6 and SWAP70 are SWEF proteins with important contributors to hematopoietic stem and precursor cells biology
Title: SWEF Proteins Distinctly Control Maintenance and Differentiation of Hematopoietic Stem Cells.
These findings reveal an important role of SWAP-70 in the dynamic spatiotemporal regulation of F-actin networks.
Title: The switch-associated protein 70 (SWAP-70) bundles actin filaments and contributes to the regulation of F-actin dynamics.
The following Swap70 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Swap70 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu03899 | |
Clone ID Related Accession (Same CDS sequence) | NM_009302.3 | |
Accession Version | NM_009302.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-16 | |
Organism | Mus musculus(house mouse) | |
Product | switch-associated protein 70 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY118458.1, AK146773.1 and BC065136.1. On Apr 29, 2009 this sequence version replaced NM_009302.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065136.1, AK146773.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGGGGCT TGAAAGACGA ACTGCTCAAA GCCATTTGGC ACGCCTTCAC CGCGCTCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_033328.3 |
CDS | 109..1866 |
Translation |
Target ORF information:
Target ORF information:
|
NM_009302.3 |
1 | ATGAGGGGCT TGAAAGACGA ACTGCTCAAA GCCATTTGGC ACGCCTTCAC CGCGCTCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu81983 | |
Clone ID Related Accession (Same CDS sequence) | XM_017322086.1 | |
Accession Version | XM_017322086.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | switch-associated protein 70 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTCCCAC CTAAGTCTCT GCCTGACAAA GATGGAAAGA AATGTCTTTT TCTAATAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017177575.1 |
CDS | 1655..2638 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017322086.1 |
1 | ATGGTCCCAC CTAAGTCTCT GCCTGACAAA GATGGAAAGA AATGTCTTTT TCTAATAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Regulation of systemic autoimmunity and CD11c |
The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity. |
Tolerogenic versus Immunogenic Lipidomic Profiles of CD11c |
SWEF Proteins Distinctly Control Maintenance and Differentiation of Hematopoietic Stem Cells. |