Gene Symbol | Gsap |
Entrez Gene ID | 212167 |
Full Name | gamma-secretase activating protein |
Synonyms | A530088I07Rik,Pion |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Gsap cDNA ORF clone
Gene Symbol | Gsap |
Entrez Gene ID | 212167 |
Full Name | gamma-secretase activating protein |
Synonyms | A530088I07Rik,Pion |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006535669.3 | XP_006535732.1 | gamma-secretase-activating protein isoform X3 |
NM_001359877.1 | NP_001346806.1 | gamma-secretase-activating protein isoform 3 |
XM_006535669.4 | XP_006535732.1 | gamma-secretase-activating protein isoform X4 |
NM_175437.3 | NP_780646.2 | gamma-secretase-activating protein isoform 1 |
XM_006535668.3 | XP_006535731.1 | gamma-secretase-activating protein isoform X2 |
NM_001359876.1 | NP_001346805.1 | gamma-secretase-activating protein isoform 2 |
XM_006535668.4 | XP_006535731.1 | gamma-secretase-activating protein isoform X3 |
XM_006535670.4 | XP_006535733.1 | gamma-secretase-activating protein isoform X5 |
XM_006535670.3 | XP_006535733.1 | gamma-secretase-activating protein isoform X4 |
XM_011249760.2 | XP_011248062.1 | gamma-secretase-activating protein isoform X1 |
XM_011249760.3 | XP_011248062.1 | gamma-secretase-activating protein isoform X1 |
XM_030254346.1 | XP_030110206.1 | gamma-secretase-activating protein isoform X2 |
XM_030254347.1 | XP_030110207.1 | gamma-secretase-activating protein isoform X2 |
Pan troglodytes (chimpanzee) | PION | XP_527798.3 |
Canis lupus familiaris (dog) | GSAP | XP_533110.3 |
PION | XP_001083448.1 | |
Homo sapiens (human) | GSAP | NP_059135.2 |
Mus musculus (house mouse) | Gsap | NP_780646.2 |
Danio rerio (zebrafish) | gsap | XP_001923138.3 |
Drosophila melanogaster (fruit fly) | pigeon | NP_476946.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008636 | XP_314733.4 |
Bos taurus (cattle) | PION | NP_001179990.1 |
Rattus norvegicus (Norway rat) | Gsap | NP_001101315.1 |
Gallus gallus (chicken) | PION | XP_004934795.1 |
Regulation of gamma-secretase activating protein by the 5Lipoxygenase: in vitro and in vivo evidence.
Chu J, Li JG, Hoffman NE, Stough AM, Madesh M, Pratic? D
Scientific reports511086(2015 Jun)
The role of ?-secretase activating protein (GSAP) and imatinib in the regulation of ?-secretase activity and amyloid-? generation.
Hussain I, Fabr?gue J, Anderes L, Ousson S, Borlat F, Eligert V, Berger S, Dimitrov M, Alattia JR, Fraering PC, Beher D
The Journal of biological chemistry288(4)2521-31(2013 Jan)
Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.
He G, Luo W, Li P, Remmers C, Netzer WJ, Hendrick J, Bettayeb K, Flajolet M, Gorelick F, Wennogle LP, Greengard P
Nature467(7311)95-8(2010 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
GSAP cleavage via caspase-3 is regulated and depend upon the availability of 5-Lipoxygenase in Alzheimer's disease.
Title: Regulation of gamma-secretase activating protein by the 5Lipoxygenase: in vitro and in vivo evidence.
gamma-secretase activating protein (GSAP) and imatinib have roles in the regulation of gamma-secretase activity and amyloid-beta generation
Title: The role of ?-secretase activating protein (GSAP) and imatinib in the regulation of ?-secretase activity and amyloid-? generation.
Study reports discovery of a novel gamma-secretase activating protein (GSAP) that selectively increases amyloid-beta production through interactions with gamma-secretase and its substrate, the amyloid precursor protein carboxy-terminal fragment.
Title: Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.
The following Gsap gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gsap cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu34745 | |
Clone ID Related Accession (Same CDS sequence) | XM_006535668.3 , XM_006535668.4 | |
Accession Version | XM_006535668.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1851bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | gamma-secretase-activating protein isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006535668.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTCTGC GGCTGGTCAC TCACTTCGAT GTGCTGGAGG ACGTGCTCCC GAGTCTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006535731.1 |
CDS | 380..2230 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006535668.3 |
1 | ATGGCTCTGC GGCTGGTCAC TCACTTCGAT GTGCTGGAGG ACGTGCTCCC GAGTCTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu34746 | |
Clone ID Related Accession (Same CDS sequence) | XM_006535669.3 , XM_006535669.4 | |
Accession Version | XM_006535669.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1842bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | gamma-secretase-activating protein isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006535669.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCCTTGG ACATAACGTT AACTGGCTTG AGATTTAAAC TTGTCAACTT TGGATATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006535732.1 |
CDS | 889..2730 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006535669.3 |
1 | ATGCCCTTGG ACATAACGTT AACTGGCTTG AGATTTAAAC TTGTCAACTT TGGATATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu34747 | |
Clone ID Related Accession (Same CDS sequence) | XM_006535670.4 , XM_006535670.3 | |
Accession Version | XM_006535670.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1662bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | gamma-secretase-activating protein isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006535670.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGTCAG TGATTCTTGA AGGATACAGA AAGATCTTCA CTGCAGCTCC TGGAAGTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006535733.1 |
CDS | 91..1752 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006535670.3 |
1 | ATGAAGTCAG TGATTCTTGA AGGATACAGA AAGATCTTCA CTGCAGCTCC TGGAAGTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu05412 | |
Clone ID Related Accession (Same CDS sequence) | NM_175437.3 | |
Accession Version | NM_175437.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2577bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-01-19 | |
Organism | Mus musculus(house mouse) | |
Product | gamma-secretase-activating protein isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC059054.1 and AK033694.1. On Dec 14, 2006 this sequence version replaced NM_175437.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK033694.1, AK170515.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTCTGC GGCTGGTCAC TCACTTCGAT GTGCTGGAGG ACGTGCTCCC GAGTCTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_780646.2 |
CDS | 97..2673 |
Translation |
Target ORF information:
Target ORF information:
|
NM_175437.3 |
1 | ATGGCTCTGC GGCTGGTCAC TCACTTCGAT GTGCTGGAGG ACGTGCTCCC GAGTCTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu72797 | |
Clone ID Related Accession (Same CDS sequence) | XM_011249760.2 , XM_011249760.3 | |
Accession Version | XM_011249760.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2322bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | gamma-secretase-activating protein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011249760.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAAGCTG TCAGTTGTTC AGTCAACAGT GAGAGAACAG TGCTTGCTGC GAGTTTCATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011248062.1 |
CDS | 176..2497 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011249760.2 |
1 | ATGCAAGCTG TCAGTTGTTC AGTCAACAGT GAGAGAACAG TGCTTGCTGC GAGTTTCATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu84174 | |
Clone ID Related Accession (Same CDS sequence) | NM_001359876.1 | |
Accession Version | NM_001359876.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2484bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-09-29 | |
Organism | Mus musculus(house mouse) | |
Product | gamma-secretase-activating protein isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113052.10. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTCTGC GGCTGGTCAC TCACTTCGAT GTGCTGGAGG ACGTGCTCCC GAGTCTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001346805.1 |
CDS | 97..2580 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001359876.1 |
1 | ATGGCTCTGC GGCTGGTCAC TCACTTCGAT GTGCTGGAGG ACGTGCTCCC GAGTCTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu84184 | |
Clone ID Related Accession (Same CDS sequence) | NM_001359877.1 | |
Accession Version | NM_001359877.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1581bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-09-29 | |
Organism | Mus musculus(house mouse) | |
Product | gamma-secretase-activating protein isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113052.10 and AK080244.1. Transcript Variant: This variant (3) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK137494.1, AK080244.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCTCTGC GGCTGGTCAC TCACTTCGAT GTGCTGGAGG ACGTGCTCCC GAGTCTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001346806.1 |
CDS | 97..1677 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001359877.1 |
1 | ATGGCTCTGC GGCTGGTCAC TCACTTCGAT GTGCTGGAGG ACGTGCTCCC GAGTCTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu34745 | |
Clone ID Related Accession (Same CDS sequence) | XM_006535668.3 , XM_006535668.4 | |
Accession Version | XM_006535668.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1851bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | gamma-secretase-activating protein isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006535668.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTCTGC GGCTGGTCAC TCACTTCGAT GTGCTGGAGG ACGTGCTCCC GAGTCTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006535731.1 |
CDS | 1113..2963 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006535668.4 |
1 | ATGGCTCTGC GGCTGGTCAC TCACTTCGAT GTGCTGGAGG ACGTGCTCCC GAGTCTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu34746 | |
Clone ID Related Accession (Same CDS sequence) | XM_006535669.3 , XM_006535669.4 | |
Accession Version | XM_006535669.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1842bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | gamma-secretase-activating protein isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006535669.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCCTTGG ACATAACGTT AACTGGCTTG AGATTTAAAC TTGTCAACTT TGGATATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006535732.1 |
CDS | 1633..3474 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006535669.4 |
1 | ATGCCCTTGG ACATAACGTT AACTGGCTTG AGATTTAAAC TTGTCAACTT TGGATATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu34747 | |
Clone ID Related Accession (Same CDS sequence) | XM_006535670.4 , XM_006535670.3 | |
Accession Version | XM_006535670.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1662bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | gamma-secretase-activating protein isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006535670.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGTCAG TGATTCTTGA AGGATACAGA AAGATCTTCA CTGCAGCTCC TGGAAGTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006535733.1 |
CDS | 99..1760 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006535670.4 |
1 | ATGAAGTCAG TGATTCTTGA AGGATACAGA AAGATCTTCA CTGCAGCTCC TGGAAGTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu72797 | |
Clone ID Related Accession (Same CDS sequence) | XM_011249760.2 , XM_011249760.3 | |
Accession Version | XM_011249760.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2322bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | gamma-secretase-activating protein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011249760.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAAGCTG TCAGTTGTTC AGTCAACAGT GAGAGAACAG TGCTTGCTGC GAGTTTCATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011248062.1 |
CDS | 491..2812 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011249760.3 |
1 | ATGCAAGCTG TCAGTTGTTC AGTCAACAGT GAGAGAACAG TGCTTGCTGC GAGTTTCATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu88851 | |
Clone ID Related Accession (Same CDS sequence) | XM_030254346.1 , XM_030254347.1 | |
Accession Version | XM_030254346.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1851bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | gamma-secretase-activating protein isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTTGAAA TGCCCTTGGA CATAACGTTA ACTGGCTTGA GATTTAAACT TGTCAACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030110206.1 |
CDS | 1789..3639 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030254346.1 |
1 | ATGTTTGAAA TGCCCTTGGA CATAACGTTA ACTGGCTTGA GATTTAAACT TGTCAACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu88851 | |
Clone ID Related Accession (Same CDS sequence) | XM_030254346.1 , XM_030254347.1 | |
Accession Version | XM_030254347.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1851bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | gamma-secretase-activating protein isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTTGAAA TGCCCTTGGA CATAACGTTA ACTGGCTTGA GATTTAAACT TGTCAACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030110207.1 |
CDS | 839..2689 |
Translation |
Target ORF information:
Target ORF information:
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XM_030254347.1 |
1 | ATGTTTGAAA TGCCCTTGGA CATAACGTTA ACTGGCTTGA GATTTAAACT TGTCAACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease. |