Gene Symbol | Txndc2 |
Entrez Gene ID | 213272 |
Full Name | thioredoxin domain containing 2 (spermatozoa) |
Synonyms | AU021712,Sptrx-1,Sptrx1,Trx4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Txndc2 cDNA ORF clone
Gene Symbol | Txndc2 |
Entrez Gene ID | 213272 |
Full Name | thioredoxin domain containing 2 (spermatozoa) |
Synonyms | AU021712,Sptrx-1,Sptrx1,Trx4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_011246354.2 | XP_011244656.1 | thioredoxin domain-containing protein 2 isoform X1 |
XM_011246354.3 | XP_011244656.1 | thioredoxin domain-containing protein 2 isoform X1 |
XM_006523986.3 | XP_006524049.1 | thioredoxin domain-containing protein 2 isoform X1 |
NM_001146002.1 | NP_001139474.1 | thioredoxin domain-containing protein 2 isoform 1 |
XM_011246354.1 | XP_011244656.1 | thioredoxin domain-containing protein 2 isoform X1 |
XM_006523986.2 | XP_006524049.1 | thioredoxin domain-containing protein 2 isoform X1 |
XM_030249623.1 | XP_030105483.1 | thioredoxin domain-containing protein 2 isoform X1 |
NM_153519.2 | NP_705739.2 | thioredoxin domain-containing protein 2 isoform 2 |
Functional deletion of Txndc2 and Txndc3 increases the susceptibility of spermatozoa to age-related oxidative stress.
Smith TB, Baker MA, Connaughton HS, Habenicht U, Aitken RJ
Free radical biology & medicine65872-81(2013 Dec)
Absolute mRNA levels and transcriptional regulation of the mouse testis-specific thioredoxins.
Jim?nez A, Prieto-Alamo MJ, Fuentes-Almagro CA, Jurado J, Gustafsson JA, Pueyo C, Miranda-Vizuete A
Biochemical and biophysical research communications330(1)65-74(2005 Apr)
Expression of Arnt and Arnt2 mRNA in developing murine tissues.
Aitola MH, Pelto-Huikko MT
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society51(1)41-54(2003 Jan)
Developmental expression of spermatid-specific thioredoxin-1 protein: transient association to the longitudinal columns of the fibrous sheath during sperm tail formation.
Yu Y, Oko R, Miranda-Vizuete A
Biology of reproduction67(5)1546-54(2002 Nov)
Cloning, expression and characterization of mouse spermatid specific thioredoxin-1 gene and protein.
Jim?nez A, Oko R, Gustafsson JA, Spyrou G, Pelto-Huikko M, Miranda-Vizuete A
Molecular human reproduction8(8)710-8(2002 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Txndc2 and Txndc3 are critically important in protecting spermatozoa against the increases in oxidative stress associated with paternal age.
Title: Functional deletion of Txndc2 and Txndc3 increases the susceptibility of spermatozoa to age-related oxidative stress.
The following Txndc2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Txndc2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu15624 | |
Clone ID Related Accession (Same CDS sequence) | NM_001146002.1 | |
Accession Version | NM_001146002.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1653bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-07-05 | |
Organism | Mus musculus(house mouse) | |
Product | thioredoxin domain-containing protein 2 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU938074.1, BC060981.1 and AV272934.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC060981.1, BU938074.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGACTTGG CCATAGAAGA AATGTTTAAG AAGGACAAAC AAAAGAATAA GGACAAGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001139474.1 |
CDS | 224..1876 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001146002.1 |
1 | ATGGACTTGG CCATAGAAGA AATGTTTAAG AAGGACAAAC AAAAGAATAA GGACAAGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15779 | |
Clone ID Related Accession (Same CDS sequence) | XM_011246354.2 , XM_011246354.3 , XM_006523986.3 , XM_011246354.1 , XM_006523986.2 , XM_030249623.1 , NM_153519.2 | |
Accession Version | NM_153519.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1632bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-24 | |
Organism | Mus musculus(house mouse) | |
Product | thioredoxin domain-containing protein 2 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF196282.2 and AV272934.1. On Mar 24, 2009 this sequence version replaced NM_153519.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and uses a downstream translational start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AF196282.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_705739.2 |
CDS | 73..1704 |
Translation |
Target ORF information:
Target ORF information:
|
NM_153519.2 |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15779 | |
Clone ID Related Accession (Same CDS sequence) | XM_011246354.2 , XM_011246354.3 , XM_006523986.3 , XM_011246354.1 , XM_006523986.2 , XM_030249623.1 , NM_153519.2 | |
Accession Version | XM_011246354.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1632bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | thioredoxin domain-containing protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011246354.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011244656.1 |
CDS | 1473..3104 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011246354.2 |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15779 | |
Clone ID Related Accession (Same CDS sequence) | XM_011246354.2 , XM_011246354.3 , XM_006523986.3 , XM_011246354.1 , XM_006523986.2 , XM_030249623.1 , NM_153519.2 | |
Accession Version | XM_011246354.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1632bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | thioredoxin domain-containing protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011246354.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011244656.1 |
CDS | 622..2253 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011246354.3 |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15779 | |
Clone ID Related Accession (Same CDS sequence) | XM_011246354.2 , XM_011246354.3 , XM_006523986.3 , XM_011246354.1 , XM_006523986.2 , XM_030249623.1 , NM_153519.2 | |
Accession Version | XM_006523986.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1632bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | thioredoxin domain-containing protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006523986.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006524049.1 |
CDS | 537..2168 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006523986.3 |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15779 | |
Clone ID Related Accession (Same CDS sequence) | XM_011246354.2 , XM_011246354.3 , XM_006523986.3 , XM_011246354.1 , XM_006523986.2 , XM_030249623.1 , NM_153519.2 | |
Accession Version | XM_011246354.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1632bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-08 | |
Organism | Mus musculus(House mouse) | |
Product | thioredoxin domain-containing protein 2 isoform X1 | |
Comment |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011244656.1 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011246354.1 |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15779 | |
Clone ID Related Accession (Same CDS sequence) | XM_011246354.2 , XM_011246354.3 , XM_006523986.3 , XM_011246354.1 , XM_006523986.2 , XM_030249623.1 , NM_153519.2 | |
Accession Version | XM_006523986.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1632bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | thioredoxin domain-containing protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006523986.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006524049.1 |
CDS | 489..2120 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006523986.2 |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15779 | |
Clone ID Related Accession (Same CDS sequence) | XM_011246354.2 , XM_011246354.3 , XM_006523986.3 , XM_011246354.1 , XM_006523986.2 , XM_030249623.1 , NM_153519.2 | |
Accession Version | XM_030249623.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1632bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | thioredoxin domain-containing protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030105483.1 |
CDS | 405..2036 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030249623.1 |
1 | ATGTTTAAGA AGGACAAACA AAAGAATAAG GACAAGGGGC TGGACATGAA CAGTGTTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Functional deletion of Txndc2 and Txndc3 increases the susceptibility of spermatozoa to age-related oxidative stress. |
Absolute mRNA levels and transcriptional regulation of the mouse testis-specific thioredoxins. |
Expression of Arnt and Arnt2 mRNA in developing murine tissues. |
Developmental expression of spermatid-specific thioredoxin-1 protein: transient association to the longitudinal columns of the fibrous sheath during sperm tail formation. |
Cloning, expression and characterization of mouse spermatid specific thioredoxin-1 gene and protein. |