Gene Symbol | Dhx33 |
Entrez Gene ID | 216877 |
Full Name | DEAH (Asp-Glu-Ala-His) box polypeptide 33 |
Synonyms | 3110057P17Rik,9430096J02Rik,Ddx33 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Dhx33 cDNA ORF clone
Gene Symbol | Dhx33 |
Entrez Gene ID | 216877 |
Full Name | DEAH (Asp-Glu-Ala-His) box polypeptide 33 |
Synonyms | 3110057P17Rik,9430096J02Rik,Ddx33 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_011248927.2 | XP_011247229.1 | putative ATP-dependent RNA helicase DHX33 isoform X2 |
XM_011248927.3 | XP_011247229.1 | ATP-dependent RNA helicase DHX33 isoform X1 |
XM_011248926.1 | XP_011247228.1 | putative ATP-dependent RNA helicase DHX33 isoform X1 |
XM_006532927.2 | XP_006532990.1 | putative ATP-dependent RNA helicase DHX33 isoform X3 |
NM_178367.4 | NP_848144.3 | ATP-dependent RNA helicase DHX33 |
Pan troglodytes (chimpanzee) | DHX33 | XP_523842.2 |
Canis lupus familiaris (dog) | DHX33 | XP_005619946.1 |
Rattus norvegicus (Norway rat) | Dhx33 | NP_001099272.1 |
Mus musculus (house mouse) | Dhx33 | NP_848144.3 |
Drosophila melanogaster (fruit fly) | CG4901 | NP_609356.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP006138 | XP_556838.3 |
Xenopus tropicalis (tropical clawed frog) | dhx33 | XP_002932324.1 |
Danio rerio (zebrafish) | LOC796505 | NP_001093527.3 |
Homo sapiens (human) | DHX33 | NP_064547.2 |
DHX33 | XP_001101396.2 | |
Gallus gallus (chicken) | DHX33 | XP_004946516.1 |
Loss of the Deubiquitinase USP36 Destabilizes the RNA Helicase DHX33 and Causes Preimplantation Lethality in Mice.
Fraile JM, Campos-Iglesias D, Rodr?guez F, Astudillo A, Vilarrasa-Blasi R, Verdaguer-Dot N, Prado MA, Paulo JA, Gygi SP, Mart?n-Subero JI, Freije JMP, L?pez-Ot?n C
The Journal of biological chemistry(2017 Dec)
High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)
The DHX33 RNA Helicase Promotes mRNA Translation Initiation.
Zhang Y, You J, Wang X, Weber J
Molecular and cellular biology35(17)2918-31(2015 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
results directly implicate DHX33 as a crucial player in establishing rRNA synthesis rates in the face of Ras(V12) or ARF signals, adjusting ribosome biogenesis to match the appropriate growth or antigrowth signals
Title: P19ARF and RasV?? offer opposing regulation of DHX33 translation to dictate tumor cell fate.
The following Dhx33 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dhx33 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu46051 | |
Clone ID Related Accession (Same CDS sequence) | XM_006532927.2 | |
Accession Version | XM_006532927.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1326bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | putative ATP-dependent RNA helicase DHX33 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006532927.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGGAGG AGGCGAGCCT CCCGCCCGCT AAGAGATTCC GGCCGGGCTC CTGCCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006532990.1 |
CDS | 175..1500 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006532927.2 |
1 | ATGCCGGAGG AGGCGAGCCT CCCGCCCGCT AAGAGATTCC GGCCGGGCTC CTGCCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu72994 | |
Clone ID Related Accession (Same CDS sequence) | XM_011248926.1 | |
Accession Version | XM_011248926.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1647bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | putative ATP-dependent RNA helicase DHX33 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGGAGG AGGCGAGCCT CCCGCCCGCT AAGAGATTCC GGCCGGGCTC CTGCCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011247228.1 |
CDS | 176..1822 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011248926.1 |
1 | ATGCCGGAGG AGGCGAGCCT CCCGCCCGCT AAGAGATTCC GGCCGGGCTC CTGCCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu72995 | |
Clone ID Related Accession (Same CDS sequence) | XM_011248927.2 , XM_011248927.3 | |
Accession Version | XM_011248927.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | putative ATP-dependent RNA helicase DHX33 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011248927.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGCGCAG TGTTTAAGGA CCAGGCCTTT CTTCCCAGGG TGTGTCTCCT GCCCATTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011247229.1 |
CDS | 11..1522 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011248927.2 |
1 | ATGTGCGCAG TGTTTAAGGA CCAGGCCTTT CTTCCCAGGG TGTGTCTCCT GCCCATTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07258 | |
Clone ID Related Accession (Same CDS sequence) | NM_178367.4 | |
Accession Version | NM_178367.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2097bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-30 | |
Organism | Mus musculus(house mouse) | |
Product | ATP-dependent RNA helicase DHX33 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK087592.1, BC052172.1 and AL596136.5. On Jun 23, 2006 this sequence version replaced NM_178367.3. ##Evidence-Data-START## Transcript exon combination :: BC027842.1, SRR1660819.69981.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164139, SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCCGGAGG AGGCGAGCCT CCCGCCCGCT AAGAGATTCC GGCCGGGCTC CTGCCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_848144.3 |
CDS | 55..2151 |
Translation |
Target ORF information:
Target ORF information:
|
NM_178367.4 |
1 | ATGCCGGAGG AGGCGAGCCT CCCGCCCGCT AAGAGATTCC GGCCGGGCTC CTGCCCTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu72995 | |
Clone ID Related Accession (Same CDS sequence) | XM_011248927.2 , XM_011248927.3 | |
Accession Version | XM_011248927.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | ATP-dependent RNA helicase DHX33 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011248927.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGCGCAG TGTTTAAGGA CCAGGCCTTT CTTCCCAGGG TGTGTCTCCT GCCCATTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011247229.1 |
CDS | 729..2240 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011248927.3 |
1 | ATGTGCGCAG TGTTTAAGGA CCAGGCCTTT CTTCCCAGGG TGTGTCTCCT GCCCATTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Loss of the Deubiquitinase USP36 Destabilizes the RNA Helicase DHX33 and Causes Preimplantation Lethality in Mice. |
High-throughput discovery of novel developmental phenotypes. |
The DHX33 RNA Helicase Promotes mRNA Translation Initiation. |