Gene Symbol | Vps41 |
Entrez Gene ID | 218035 |
Full Name | VPS41 HOPS complex subunit |
Synonyms | AI317346,Vam2,mVam2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Vps41 cDNA ORF clone
gRNAs
Gene Symbol | Vps41 |
Entrez Gene ID | 218035 |
Full Name | VPS41 HOPS complex subunit |
Synonyms | AI317346,Vam2,mVam2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006516641.3 | XP_006516704.1 | vacuolar protein sorting-associated protein 41 homolog isoform X1 |
NM_172120.4 | NP_742118.3 | vacuolar protein sorting-associated protein 41 homolog |
XM_006516641.2 | XP_006516704.1 | vacuolar protein sorting-associated protein 41 homolog isoform X1 |
Canis lupus familiaris (dog) | VPS41 | XP_533084.2 |
Mus musculus (house mouse) | Vps41 | NP_742118.3 |
Oryza sativa (rice) | Os04g0195000 | NP_001052213.1 |
Xenopus tropicalis (tropical clawed frog) | vps41 | XP_004912577.1 |
Pan troglodytes (chimpanzee) | VPS41 | XP_519057.3 |
VPS41 | XP_001101460.2 | |
Rattus norvegicus (Norway rat) | Vps41 | NP_001100825.1 |
Drosophila melanogaster (fruit fly) | lt | NP_001260695.1 |
Homo sapiens (human) | VPS41 | NP_055211.2 |
Danio rerio (zebrafish) | vps41 | XP_691671.2 |
Bos taurus (cattle) | VPS41 | NP_001076922.1 |
Gallus gallus (chicken) | VPS41 | NP_001012877.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP009174 | XP_319939.4 |
Arabidopsis thaliana (thale cress) | VPS41 | NP_172297.2 |
Impaired stimulation of p38?-MAPK/Vps41-HOPS by LPS from pathogenic Coxiella burnetii prevents trafficking to microbicidal phagolysosomes.
Barry AO, Boucherit N, Mottola G, Vadovic P, Trouplin V, Soubeyran P, Capo C, Bonatti S, Nebreda A, Toman R, Lemichez E, Mege JL, Ghigo E
Cell host & microbe12(6)751-63(2012 Dec)
Spatial restriction of bone morphogenetic protein signaling in mouse gastrula through the mVam2-dependent endocytic pathway.
Aoyama M, Sun-Wada GH, Yamamoto A, Yamamoto M, Hamada H, Wada Y
Developmental cell22(6)1163-75(2012 Jun)
Simple and straightforward construction of a mouse gene targeting vector using in vitro transposition reactions.
Aoyama M, Agari K, Sun-Wada GH, Futai M, Wada Y
Nucleic acids research33(5)e52(2005 Mar)
Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton.
Richardson SC, Winistorfer SC, Poupon V, Luzio JP, Piper RC
Molecular biology of the cell15(3)1197-210(2004 Mar)
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Lack of Coxiella burnetii targeting to degradative compartments involves an antagonistic engagement of TLR4 by lipopolysaccharides, lack of p38alpha-MAPK-driven phosphorylation, and block in recruitment of the Vps41 to lipopolysaccharide-containing vesicles.
Title: Impaired stimulation of p38?-MAPK/Vps41-HOPS by LPS from pathogenic Coxiella burnetii prevents trafficking to microbicidal phagolysosomes.
It was found that Vam2, which interacts with BMP type I receptor, is required for the spatiotemporal modulation of BMP signaling, via sequestration of the receptor complex in the late stages of the endocytic pathway.
Title: Spatial restriction of bone morphogenetic protein signaling in mouse gastrula through the mVam2-dependent endocytic pathway.
The following Vps41 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Vps41 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu03194 | |
Clone ID Related Accession (Same CDS sequence) | NM_172120.4 | |
Accession Version | NM_172120.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2562bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-20 | |
Organism | Mus musculus(house mouse) | |
Product | vacuolar protein sorting-associated protein 41 homolog | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB028843.1 and AI851542.1. On Dec 29, 2009 this sequence version replaced NM_172120.3. ##Evidence-Data-START## Transcript exon combination :: AB028843.1, AK164177.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGGAAG CAGAGGAGCA GGAAACCGAG TCTCTTGAAG AATCTACGGA TGAGTCAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_742118.3 |
CDS | 25..2586 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCGGAAG CAGAGGAGCA GGAAACCGAG TCTCTTGAAG AATCTACGGA TGAGTCAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu48369 | |
Clone ID Related Accession (Same CDS sequence) | XM_006516641.3 , XM_006516641.2 | |
Accession Version | XM_006516641.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2091bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | vacuolar protein sorting-associated protein 41 homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006516641.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACAGAT GGAAGTCTTC TGTGCTACAC GAAGGGGAAG GAAACATAAG GAGTGTGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006516704.1 |
CDS | 7115..9205 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAACAGAT GGAAGTCTTC TGTGCTACAC GAAGGGGAAG GAAACATAAG GAGTGTGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu48369 | |
Clone ID Related Accession (Same CDS sequence) | XM_006516641.3 , XM_006516641.2 | |
Accession Version | XM_006516641.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2091bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | vacuolar protein sorting-associated protein 41 homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006516641.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACAGAT GGAAGTCTTC TGTGCTACAC GAAGGGGAAG GAAACATAAG GAGTGTGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006516704.1 |
CDS | 10355..12445 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAACAGAT GGAAGTCTTC TGTGCTACAC GAAGGGGAAG GAAACATAAG GAGTGTGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Impaired stimulation of p38?-MAPK/Vps41-HOPS by LPS from pathogenic Coxiella burnetii prevents trafficking to microbicidal phagolysosomes. |
Spatial restriction of bone morphogenetic protein signaling in mouse gastrula through the mVam2-dependent endocytic pathway. |
Simple and straightforward construction of a mouse gene targeting vector using in vitro transposition reactions. |
Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton. |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |