Gene Symbol | Trip6 |
Entrez Gene ID | 22051 |
Full Name | thyroid hormone receptor interactor 6 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Trip6 cDNA ORF clone
Gene Symbol | Trip6 |
Entrez Gene ID | 22051 |
Full Name | thyroid hormone receptor interactor 6 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_011639.3 | NP_035769.1 | thyroid receptor-interacting protein 6 |
XM_006504563.3 | XP_006504626.1 | thyroid receptor-interacting protein 6 isoform X1 |
Pan troglodytes (chimpanzee) | TRIP6 | NP_001233552.1 |
Canis lupus familiaris (dog) | TRIP6 | XP_536859.1 |
Bos taurus (cattle) | TRIP6 | NP_001030546.1 |
Homo sapiens (human) | TRIP6 | NP_003293.2 |
Mus musculus (house mouse) | Trip6 | NP_035769.1 |
Rattus norvegicus (Norway rat) | Trip6 | NP_001121042.1 |
Danio rerio (zebrafish) | LOC792697 | XP_005172284.1 |
The LIM domain protein nTRIP6 acts as a co-repressor for the transcription factor MEF2C in myoblasts.
Kemler D, Dahley O, Ro?wag S, Litfin M, Kassel O
Scientific reports627746(2016 Jun)
Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization.
Lv K, Chen L, Li Y, Li Z, Zheng P, Liu Y, Chen J, Teng J
The Journal of neuroscience : the official journal of the Society for Neuroscience35(6)2559-71(2015 Feb)
TRIP6 regulates neural stem cell maintenance in the postnatal mammalian subventricular zone.
Lai YJ, Li MY, Yang CY, Huang KH, Tsai JC, Wang TW
Developmental dynamics : an official publication of the American Association of Anatomists243(9)1130-42(2014 Sep)
TRIP6: an adaptor protein that regulates cell motility, antiapoptotic signaling and transcriptional activity.
Lin VT, Lin FT
Cellular signalling23(11)1691-7(2011 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Our data suggest that TRIP6 regulates neural stem cell maintenance and it may be a new marker for neural stem cells.
Title: TRIP6 regulates neural stem cell maintenance in the postnatal mammalian subventricular zone.
TRIP6 is an adaptor protein that regulates cell motility, antiapoptotic signaling and transcriptional activity. (Review)
Title: TRIP6: an adaptor protein that regulates cell motility, antiapoptotic signaling and transcriptional activity.
Data show that OIP-1 (Trip6) is an important physiologic regulator of osteoclast development and may have therapeutic utility for bone diseases with high bone turnover.
Title: Osteoclast inhibitory peptide-1 binding to the Fc gammaRIIB inhibits osteoclast differentiation.
TRIP6 is a critical downstream regulator of c-Src signaling and its phosphorylation is permissive for its presence in the sealing zone where it plays a positive role in osteoclast bone resorptive capacity
Title: c-Src-mediated phosphorylation of thyroid hormone receptor-interacting protein 6 (TRIP6) promotes osteoclast sealing zone formation.
nTrip6 serves as the molecular mediator of the crosstalk between nuclear receptors and other transcription factors in that it assembles these factors at promoters.
Title: The nuclear isoform of the LIM domain protein Trip6 integrates activating and repressing signals at the promoter-bound glucocorticoid receptor.
The following Trip6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Trip6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu08503 | |
Clone ID Related Accession (Same CDS sequence) | NM_011639.3 | |
Accession Version | NM_011639.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1443bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-23 | |
Organism | Mus musculus(house mouse) | |
Product | thyroid receptor-interacting protein 6 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK010435.1. On Apr 5, 2007 this sequence version replaced NM_011639.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK010435.1, AK166024.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN01164133 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCCGGGC CCACCTGGCT TCCCCCGAAG CAGCCAGAAC CCTCCAGACT CCCTCAGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_035769.1 |
CDS | 174..1616 |
Translation |
Target ORF information:
Target ORF information:
|
NM_011639.3 |
1 | ATGTCCGGGC CCACCTGGCT TCCCCCGAAG CAGCCAGAAC CCTCCAGACT CCCTCAGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36222 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504563.3 | |
Accession Version | XM_006504563.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | thyroid receptor-interacting protein 6 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504563.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCGGGC CCACCTGGCT TCCCCCGAAG CAGCCAGAAC CCTCCAGACT CCCTCAGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504626.1 |
CDS | 434..1654 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504563.3 |
1 | ATGTCCGGGC CCACCTGGCT TCCCCCGAAG CAGCCAGAAC CCTCCAGACT CCCTCAGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The LIM domain protein nTRIP6 acts as a co-repressor for the transcription factor MEF2C in myoblasts. |
Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization. |
TRIP6 regulates neural stem cell maintenance in the postnatal mammalian subventricular zone. |
TRIP6: an adaptor protein that regulates cell motility, antiapoptotic signaling and transcriptional activity. |