Gene Symbol | Vil1 |
Entrez Gene ID | 22349 |
Full Name | villin 1 |
Synonyms | Vil |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Vil1 cDNA ORF clone
gRNAs
Gene Symbol | Vil1 |
Entrez Gene ID | 22349 |
Full Name | villin 1 |
Synonyms | Vil |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_009509.2 | NP_033535.2 | villin-1 |
VIL1 | XP_001090524.1 | |
Bos taurus (cattle) | VIL1 | NP_001013609.1 |
Mus musculus (house mouse) | Vil1 | NP_033535.2 |
Arabidopsis thaliana (thale cress) | AT5G57320 | NP_200542.1 |
Arabidopsis thaliana (thale cress) | VLN4 | NP_194745.1 |
Xenopus tropicalis (tropical clawed frog) | vil1 | NP_001096367.1 |
Gallus gallus (chicken) | VIL1 | NP_990773.1 |
Homo sapiens (human) | VIL1 | NP_009058.2 |
Pan troglodytes (chimpanzee) | VIL1 | XP_001157250.2 |
Danio rerio (zebrafish) | vil1 | NP_956532.1 |
Oryza sativa (rice) | Os08g0240800 | NP_001061335.1 |
Oryza sativa (rice) | Os06g0659300 | NP_001058263.1 |
Canis lupus familiaris (dog) | VIL1 | XP_545642.2 |
Rattus norvegicus (Norway rat) | Vil1 | NP_001101694.1 |
Oryza sativa (rice) | Os04g0604000 | NP_001053784.1 |
Villin-1 and Gelsolin Regulate Changes in Actin Dynamics That Affect Cell Survival Signaling Pathways and Intestinal Inflammation.
Roy S, Esmaeilniakooshkghazi A, Patnaik S, Wang Y, George SP, Ahrorov A, Hou JK, Herron AJ, Sesaki H, Khurana S
Gastroenterology(2017 Dec)
Trpm5 expression in the olfactory epithelium.
Pyrski M, Eckstein E, Schmid A, Bufe B, Weiss J, Chubanov V, Boehm U, Zufall F
Molecular and cellular neurosciences8075-88(2017 04)
Both the anti- and pro-apoptotic functions of villin regulate cell turnover and intestinal homeostasis.
Wang Y, George SP, Roy S, Pham E, Esmaeilniakooshkghazi A, Khurana S
Scientific reports635491(2016 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Competition between tryptophan fluorescence and electron transfer during unfolding of the villin headpiece.
Title: Competition between tryptophan fluorescence and electron transfer during unfolding of the villin headpiece.
villin severs F-actin to ensure microvillus depolarization and enterocyte remodeling upon intestinal injury
Title: Enterocyte loss of polarity and gut wound healing rely upon the F-actin-severing function of villin.
Villin-Cre(+);Klf4(fl/fl) have greater susceptibility to chemical-induced gastric carcinogenesis and increased rates of gastric tumor progression than control mice.
Title: Disruption of Klf4 in villin-positive gastric progenitor cells promotes formation and progression of tumors of the antrum in mice.
The data establish that meprins interact with and cleave villin and actin, and these cytoskeletal proteins are substrates for meprins.
Title: Villin and actin in the mouse kidney brush-border membrane bind to and are degraded by meprins, an interaction that contributes to injury in ischemia-reperfusion.
Villin is an actin regulatory protein that organizes, integrates and regulates multiple epithelial cell functions.
Title: Regulation of cell structure and function by actin-binding proteins: villin's perspective.
The following Vil1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Vil1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu18099 | |
Clone ID Related Accession (Same CDS sequence) | NM_009509.2 | |
Accession Version | NM_009509.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2484bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-20 | |
Organism | Mus musculus(house mouse) | |
Product | villin-1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB871941.1, AK027908.1, AI663456.1 and BY426484.1. On Jun 19, 2008 this sequence version replaced NM_009509.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC015267.1, AK027908.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849376, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGACTAAAC TGAATGCCCA AGTCAAAGGC TCTCTCAACA TCACCACTCC CGGGATACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_033535.2 |
CDS | 65..2548 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGACTAAAC TGAATGCCCA AGTCAAAGGC TCTCTCAACA TCACCACTCC CGGGATACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Villin-1 and Gelsolin Regulate Changes in Actin Dynamics That Affect Cell Survival Signaling Pathways and Intestinal Inflammation. |
Trpm5 expression in the olfactory epithelium. |
Both the anti- and pro-apoptotic functions of villin regulate cell turnover and intestinal homeostasis. |