| Gene Symbol | Thoc1 |
| Entrez Gene ID | 225160 |
| Full Name | THO complex 1 |
| Synonyms | 3110002N20Rik,AW107452,NMP-84 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
gRNAs
The following Thoc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Thoc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu17525 | |
| Clone ID Related Accession (Same CDS sequence) | NM_153552.3 | |
| Accession Version | NM_153552.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-06-06 | |
| Organism | Mus musculus(house mouse) | |
| Product | THO complex subunit 1 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK031785.1. On Apr 6, 2007 this sequence version replaced NM_153552.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK031785.1, AK167374.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTCTCCGA CGCCGGCGCT TTTCAGTTTG CCGGAGGCGC GGACGCGATT TACGAAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_705780.1 |
| CDS | 14..1987 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_153552.3 |
1 | ATGTCTCCGA CGCCGGCGCT TTTCAGTTTG CCGGAGGCGC GGACGCGATT TACGAAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu73233 | |
| Clone ID Related Accession (Same CDS sequence) | XM_030250419.1 | |
| Accession Version | XM_030250419.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1560bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | THO complex subunit 1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTGCAATG ATCTCCTCAG AAGATTGTCT AAATCTCAGA ATACAGTTTT CTGTGGAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_030106279.1 |
| CDS | 472..2031 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_030250419.1 |
1 | ATGTGCAATG ATCTCCTCAG AAGATTGTCT AAATCTCAGA ATACAGTTTT CTGTGGAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Evaluating Effects of Hypomorphic Thoc1 Alleles on Embryonic Development in Rb1 Null Mice. |
The Thoc1 ribonucleoprotein and prostate cancer progression. |
The Thoc1 encoded ribonucleoprotein is required for myeloid progenitor cell homeostasis in the adult mouse. |
The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogramming. |
The THO ribonucleoprotein complex is required for stem cell homeostasis in the adult mouse small intestine. |
