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Erlin1 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Erlin1
Entrez Gene ID 226144
Full Name ER lipid raft associated 1
Synonyms 2810439N09Rik,C80197,Keo4,Spfh1
General protein information
Preferred Names

ER lipid raft associated 1

Names

erlin-1
SPFH domain family, member 1
SPFH domain-containing protein 1
endoplasmic reticulum lipid raft-associated protein 1
protein KE04 homolog
stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

19

19|19 C3

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001164360.1 NP_001157832.1 erlin-1
NM_145502.3 NP_663477.3 erlin-1
XM_006526998.3 XP_006527061.1 erlin-1 isoform X1
NM_001164359.1 NP_001157831.1 erlin-1
XM_006526998.4 XP_006527061.1 erlin-1 isoform X1

Pathways from BioSystems


Homologies


Homo sapiens (human) ERLIN1 NP_001094096.1
Canis lupus familiaris (dog) ERLIN1 XP_005637667.1
ERLIN1 XP_001107293.1
Mus musculus (house mouse) Erlin1 NP_663477.3
Rattus norvegicus (Norway rat) Erlin1 NP_001099823.1
Gallus gallus (chicken) ERLIN1 NP_001026394.1
Danio rerio (zebrafish) erlin1 NP_001014325.1
Pan troglodytes (chimpanzee) ERLIN1 XP_001167929.2
Bos taurus (cattle) ERLIN1 NP_001157504.1
Xenopus tropicalis (tropical clawed frog) erlin1 NP_001016892.1

Gene Ontology


Bibliography

Related articles in PubMed

Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis.
Huber MD, Vesely PW, Datta K, Gerace L
The Journal of cell biology203(3)427-36(2013 Nov)

Clustered hydrophobic amino acids in amphipathic helices mediate erlin1/2 complex assembly.
Pednekar D, Wang Y, Fedotova TV, Wojcikiewicz RJ
Biochemical and biophysical research communications415(1)135-40(2011 Nov)

An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors.
Pearce MM, Wormer DB, Wilkens S, Wojcikiewicz RJ
The Journal of biological chemistry284(16)10433-45(2009 Apr)

Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.
Lyssand JS, DeFino MC, Tang XB, Hertz AL, Feller DB, Wacker JL, Adams ME, Hague C
The Journal of biological chemistry283(27)18792-800(2008 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Erlin1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Erlin1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu22596 NM_001164360.1
Latest version!		 Mus musculus ER lipid raft associated 1 (Erlin1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $188.30
$269.00
OMu22596 NM_001164359.1
Latest version!		 Mus musculus ER lipid raft associated 1 (Erlin1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $188.30
$269.00
OMu22596 NM_145502.3
Latest version!		 Mus musculus ER lipid raft associated 1 (Erlin1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $188.30
$269.00
OMu22596 XM_006526998.4
Latest version!		 Mus musculus ER lipid raft associated 1 (Erlin1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $223.30
$319.00
View Old Accession Versions >>
OMu22596 XM_006526998.3 Mus musculus ER lipid raft associated 1 (Erlin1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $188.30
$269.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu22596
Clone ID Related Accession (Same CDS sequence) NM_001164360.1 , NM_145502.3 , XM_006526998.3 , NM_001164359.1 , XM_006526998.4
Accession Version NM_001164360.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1047bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-26
Organism Mus musculus(house mouse)
Product erlin-1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ074662.1, AK145990.1, BM205368.2 and BE990958.1. Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. All three variants encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC011220.1, AK145990.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGAATATGA CTCAAGCCCG GCTTCTGGTG GCTGCAGTGG TGGGGTTGGT GGCGATCCTC 
CTGTACGCCT CCATCCACAA GATCGAAGAG GGACACTTGG CCGTGTACTA CAGGGGAGGA 
GCTTTGCTAA CGAGCCCCAG TGGACCAGGC TATCATATCA TGTTGCCTTT CATTACAACA 
TTCAGATCTG TGCAGACAAC ACTACAAACG GATGAAGTTA AAAATGTGCC TTGTGGAACA 
AGTGGTGGAG TCATGATCTA TATTGACCGA ATAGAAGTGG TTAATATGTT GGCTCCTTAT 
GCAGTGTTTG ACATTGTGAG GAACTATACT GCAGACTACG ACAAGACTTT AATCTTCAAT 
AAAATCCACC ATGAGCTGAA CCAGTTTTGC AGTGCCCACA CACTTCAAGA AGTTTACATA 
GAATTGTTTG ATCAAATAGA TGAAAACCTG AAGCAGGCCC TGCAAAAAGA TTTAAACACC 
ATGGCCCCAG GTCTCACTAT CCAGGCTGTG CGTGTTACAA AACCCAAAAT CCCAGAAGCC 
ATAAGAAGAA ATTTTGAATT AATGGAGGCA GAGAAGACAA AACTTCTCAT AGCTGCACAG 
AAACAAAAGG TGGTGGAGAA AGAAGCTGAG ACGGAGAGGA AAAGGGCTGT TATAGAAGCA 
GAGAAGATTG CACAAGTAGC AAAAATTCGA TTTCAACAGA AAGTGATGGA GAAAGAAACT 
GAAAAACGCA TTTCTGAGAT TGAAGATGCT GCGTTCCTGG CCCGAGAGAA GGCAAAAGCA 
GATGCCGAGT ATTACGCTGC ACACAAATAC GCCACCTCAA ACAAGCACAA ACTGACCCCA 
GAGTATCTGG AGCTCAAGAA ATACCAGGCC ATTGCCTCAA ACAGTAAGAT CTACTTTGGC 
AGCAACATCC CCAGCATGTT TGTGGACTCC TCCTGTGCTC TGAAATACTC TGATGGTAGG 
ACTGGGAGAG AAGACTCCCT TCCCCCAGAG GAGGCCCGTG AGCCCTCTGG AGAGAGCCCC 
ATCCAAAACA AGGAGAACGC AGGTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001157832.1
CDS107..1153
Translation

Target ORF information:

RefSeq Version NM_001164360.1
Organism Mus musculus(house mouse)
Definition Mus musculus ER lipid raft associated 1 (Erlin1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001164360.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGAATATGA CTCAAGCCCG GCTTCTGGTG GCTGCAGTGG TGGGGTTGGT GGCGATCCTC 
CTGTACGCCT CCATCCACAA GATCGAAGAG GGACACTTGG CCGTGTACTA CAGGGGAGGA 
GCTTTGCTAA CGAGCCCCAG TGGACCAGGC TATCATATCA TGTTGCCTTT CATTACAACA 
TTCAGATCTG TGCAGACAAC ACTACAAACG GATGAAGTTA AAAATGTGCC TTGTGGAACA 
AGTGGTGGAG TCATGATCTA TATTGACCGA ATAGAAGTGG TTAATATGTT GGCTCCTTAT 
GCAGTGTTTG ACATTGTGAG GAACTATACT GCAGACTACG ACAAGACTTT AATCTTCAAT 
AAAATCCACC ATGAGCTGAA CCAGTTTTGC AGTGCCCACA CACTTCAAGA AGTTTACATA 
GAATTGTTTG ATCAAATAGA TGAAAACCTG AAGCAGGCCC TGCAAAAAGA TTTAAACACC 
ATGGCCCCAG GTCTCACTAT CCAGGCTGTG CGTGTTACAA AACCCAAAAT CCCAGAAGCC 
ATAAGAAGAA ATTTTGAATT AATGGAGGCA GAGAAGACAA AACTTCTCAT AGCTGCACAG 
AAACAAAAGG TGGTGGAGAA AGAAGCTGAG ACGGAGAGGA AAAGGGCTGT TATAGAAGCA 
GAGAAGATTG CACAAGTAGC AAAAATTCGA TTTCAACAGA AAGTGATGGA GAAAGAAACT 
GAAAAACGCA TTTCTGAGAT TGAAGATGCT GCGTTCCTGG CCCGAGAGAA GGCAAAAGCA 
GATGCCGAGT ATTACGCTGC ACACAAATAC GCCACCTCAA ACAAGCACAA ACTGACCCCA 
GAGTATCTGG AGCTCAAGAA ATACCAGGCC ATTGCCTCAA ACAGTAAGAT CTACTTTGGC 
AGCAACATCC CCAGCATGTT TGTGGACTCC TCCTGTGCTC TGAAATACTC TGATGGTAGG 
ACTGGGAGAG AAGACTCCCT TCCCCCAGAG GAGGCCCGTG AGCCCTCTGG AGAGAGCCCC 
ATCCAAAACA AGGAGAACGC AGGTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu22596
Clone ID Related Accession (Same CDS sequence) NM_001164360.1 , NM_145502.3 , XM_006526998.3 , NM_001164359.1 , XM_006526998.4
Accession Version NM_145502.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1047bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-27
Organism Mus musculus(house mouse)
Product erlin-1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN702299.1, AK133557.1 and BE990958.1. On Aug 21, 2009 this sequence version replaced NM_145502.2. Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.206202.1, AK133557.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGAATATGA CTCAAGCCCG GCTTCTGGTG GCTGCAGTGG TGGGGTTGGT GGCGATCCTC 
CTGTACGCCT CCATCCACAA GATCGAAGAG GGACACTTGG CCGTGTACTA CAGGGGAGGA 
GCTTTGCTAA CGAGCCCCAG TGGACCAGGC TATCATATCA TGTTGCCTTT CATTACAACA 
TTCAGATCTG TGCAGACAAC ACTACAAACG GATGAAGTTA AAAATGTGCC TTGTGGAACA 
AGTGGTGGAG TCATGATCTA TATTGACCGA ATAGAAGTGG TTAATATGTT GGCTCCTTAT 
GCAGTGTTTG ACATTGTGAG GAACTATACT GCAGACTACG ACAAGACTTT AATCTTCAAT 
AAAATCCACC ATGAGCTGAA CCAGTTTTGC AGTGCCCACA CACTTCAAGA AGTTTACATA 
GAATTGTTTG ATCAAATAGA TGAAAACCTG AAGCAGGCCC TGCAAAAAGA TTTAAACACC 
ATGGCCCCAG GTCTCACTAT CCAGGCTGTG CGTGTTACAA AACCCAAAAT CCCAGAAGCC 
ATAAGAAGAA ATTTTGAATT AATGGAGGCA GAGAAGACAA AACTTCTCAT AGCTGCACAG 
AAACAAAAGG TGGTGGAGAA AGAAGCTGAG ACGGAGAGGA AAAGGGCTGT TATAGAAGCA 
GAGAAGATTG CACAAGTAGC AAAAATTCGA TTTCAACAGA AAGTGATGGA GAAAGAAACT 
GAAAAACGCA TTTCTGAGAT TGAAGATGCT GCGTTCCTGG CCCGAGAGAA GGCAAAAGCA 
GATGCCGAGT ATTACGCTGC ACACAAATAC GCCACCTCAA ACAAGCACAA ACTGACCCCA 
GAGTATCTGG AGCTCAAGAA ATACCAGGCC ATTGCCTCAA ACAGTAAGAT CTACTTTGGC 
AGCAACATCC CCAGCATGTT TGTGGACTCC TCCTGTGCTC TGAAATACTC TGATGGTAGG 
ACTGGGAGAG AAGACTCCCT TCCCCCAGAG GAGGCCCGTG AGCCCTCTGG AGAGAGCCCC 
ATCCAAAACA AGGAGAACGC AGGTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_663477.3
CDS303..1349
Translation

Target ORF information:

RefSeq Version NM_145502.3
Organism Mus musculus(house mouse)
Definition Mus musculus ER lipid raft associated 1 (Erlin1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_145502.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGAATATGA CTCAAGCCCG GCTTCTGGTG GCTGCAGTGG TGGGGTTGGT GGCGATCCTC 
CTGTACGCCT CCATCCACAA GATCGAAGAG GGACACTTGG CCGTGTACTA CAGGGGAGGA 
GCTTTGCTAA CGAGCCCCAG TGGACCAGGC TATCATATCA TGTTGCCTTT CATTACAACA 
TTCAGATCTG TGCAGACAAC ACTACAAACG GATGAAGTTA AAAATGTGCC TTGTGGAACA 
AGTGGTGGAG TCATGATCTA TATTGACCGA ATAGAAGTGG TTAATATGTT GGCTCCTTAT 
GCAGTGTTTG ACATTGTGAG GAACTATACT GCAGACTACG ACAAGACTTT AATCTTCAAT 
AAAATCCACC ATGAGCTGAA CCAGTTTTGC AGTGCCCACA CACTTCAAGA AGTTTACATA 
GAATTGTTTG ATCAAATAGA TGAAAACCTG AAGCAGGCCC TGCAAAAAGA TTTAAACACC 
ATGGCCCCAG GTCTCACTAT CCAGGCTGTG CGTGTTACAA AACCCAAAAT CCCAGAAGCC 
ATAAGAAGAA ATTTTGAATT AATGGAGGCA GAGAAGACAA AACTTCTCAT AGCTGCACAG 
AAACAAAAGG TGGTGGAGAA AGAAGCTGAG ACGGAGAGGA AAAGGGCTGT TATAGAAGCA 
GAGAAGATTG CACAAGTAGC AAAAATTCGA TTTCAACAGA AAGTGATGGA GAAAGAAACT 
GAAAAACGCA TTTCTGAGAT TGAAGATGCT GCGTTCCTGG CCCGAGAGAA GGCAAAAGCA 
GATGCCGAGT ATTACGCTGC ACACAAATAC GCCACCTCAA ACAAGCACAA ACTGACCCCA 
GAGTATCTGG AGCTCAAGAA ATACCAGGCC ATTGCCTCAA ACAGTAAGAT CTACTTTGGC 
AGCAACATCC CCAGCATGTT TGTGGACTCC TCCTGTGCTC TGAAATACTC TGATGGTAGG 
ACTGGGAGAG AAGACTCCCT TCCCCCAGAG GAGGCCCGTG AGCCCTCTGG AGAGAGCCCC 
ATCCAAAACA AGGAGAACGC AGGTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu22596
Clone ID Related Accession (Same CDS sequence) NM_001164360.1 , NM_145502.3 , XM_006526998.3 , NM_001164359.1 , XM_006526998.4
Accession Version NM_001164359.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1047bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-27
Organism Mus musculus(house mouse)
Product erlin-1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC124693.4, CJ134812.1, AK145990.1, BM205368.2 and BE990958.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. All three variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## CDS exon combination :: BC011220.1, AK133557.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGAATATGA CTCAAGCCCG GCTTCTGGTG GCTGCAGTGG TGGGGTTGGT GGCGATCCTC 
CTGTACGCCT CCATCCACAA GATCGAAGAG GGACACTTGG CCGTGTACTA CAGGGGAGGA 
GCTTTGCTAA CGAGCCCCAG TGGACCAGGC TATCATATCA TGTTGCCTTT CATTACAACA 
TTCAGATCTG TGCAGACAAC ACTACAAACG GATGAAGTTA AAAATGTGCC TTGTGGAACA 
AGTGGTGGAG TCATGATCTA TATTGACCGA ATAGAAGTGG TTAATATGTT GGCTCCTTAT 
GCAGTGTTTG ACATTGTGAG GAACTATACT GCAGACTACG ACAAGACTTT AATCTTCAAT 
AAAATCCACC ATGAGCTGAA CCAGTTTTGC AGTGCCCACA CACTTCAAGA AGTTTACATA 
GAATTGTTTG ATCAAATAGA TGAAAACCTG AAGCAGGCCC TGCAAAAAGA TTTAAACACC 
ATGGCCCCAG GTCTCACTAT CCAGGCTGTG CGTGTTACAA AACCCAAAAT CCCAGAAGCC 
ATAAGAAGAA ATTTTGAATT AATGGAGGCA GAGAAGACAA AACTTCTCAT AGCTGCACAG 
AAACAAAAGG TGGTGGAGAA AGAAGCTGAG ACGGAGAGGA AAAGGGCTGT TATAGAAGCA 
GAGAAGATTG CACAAGTAGC AAAAATTCGA TTTCAACAGA AAGTGATGGA GAAAGAAACT 
GAAAAACGCA TTTCTGAGAT TGAAGATGCT GCGTTCCTGG CCCGAGAGAA GGCAAAAGCA 
GATGCCGAGT ATTACGCTGC ACACAAATAC GCCACCTCAA ACAAGCACAA ACTGACCCCA 
GAGTATCTGG AGCTCAAGAA ATACCAGGCC ATTGCCTCAA ACAGTAAGAT CTACTTTGGC 
AGCAACATCC CCAGCATGTT TGTGGACTCC TCCTGTGCTC TGAAATACTC TGATGGTAGG 
ACTGGGAGAG AAGACTCCCT TCCCCCAGAG GAGGCCCGTG AGCCCTCTGG AGAGAGCCCC 
ATCCAAAACA AGGAGAACGC AGGTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001157831.1
CDS199..1245
Translation

Target ORF information:

RefSeq Version NM_001164359.1
Organism Mus musculus(house mouse)
Definition Mus musculus ER lipid raft associated 1 (Erlin1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001164359.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGAATATGA CTCAAGCCCG GCTTCTGGTG GCTGCAGTGG TGGGGTTGGT GGCGATCCTC 
CTGTACGCCT CCATCCACAA GATCGAAGAG GGACACTTGG CCGTGTACTA CAGGGGAGGA 
GCTTTGCTAA CGAGCCCCAG TGGACCAGGC TATCATATCA TGTTGCCTTT CATTACAACA 
TTCAGATCTG TGCAGACAAC ACTACAAACG GATGAAGTTA AAAATGTGCC TTGTGGAACA 
AGTGGTGGAG TCATGATCTA TATTGACCGA ATAGAAGTGG TTAATATGTT GGCTCCTTAT 
GCAGTGTTTG ACATTGTGAG GAACTATACT GCAGACTACG ACAAGACTTT AATCTTCAAT 
AAAATCCACC ATGAGCTGAA CCAGTTTTGC AGTGCCCACA CACTTCAAGA AGTTTACATA 
GAATTGTTTG ATCAAATAGA TGAAAACCTG AAGCAGGCCC TGCAAAAAGA TTTAAACACC 
ATGGCCCCAG GTCTCACTAT CCAGGCTGTG CGTGTTACAA AACCCAAAAT CCCAGAAGCC 
ATAAGAAGAA ATTTTGAATT AATGGAGGCA GAGAAGACAA AACTTCTCAT AGCTGCACAG 
AAACAAAAGG TGGTGGAGAA AGAAGCTGAG ACGGAGAGGA AAAGGGCTGT TATAGAAGCA 
GAGAAGATTG CACAAGTAGC AAAAATTCGA TTTCAACAGA AAGTGATGGA GAAAGAAACT 
GAAAAACGCA TTTCTGAGAT TGAAGATGCT GCGTTCCTGG CCCGAGAGAA GGCAAAAGCA 
GATGCCGAGT ATTACGCTGC ACACAAATAC GCCACCTCAA ACAAGCACAA ACTGACCCCA 
GAGTATCTGG AGCTCAAGAA ATACCAGGCC ATTGCCTCAA ACAGTAAGAT CTACTTTGGC 
AGCAACATCC CCAGCATGTT TGTGGACTCC TCCTGTGCTC TGAAATACTC TGATGGTAGG 
ACTGGGAGAG AAGACTCCCT TCCCCCAGAG GAGGCCCGTG AGCCCTCTGG AGAGAGCCCC 
ATCCAAAACA AGGAGAACGC AGGTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu22596
Clone ID Related Accession (Same CDS sequence) NM_001164360.1 , NM_145502.3 , XM_006526998.3 , NM_001164359.1 , XM_006526998.4
Accession Version XM_006526998.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1047bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product erlin-1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006526998.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGAATATGA CTCAAGCCCG GCTTCTGGTG GCTGCAGTGG TGGGGTTGGT GGCGATCCTC 
CTGTACGCCT CCATCCACAA GATCGAAGAG GGACACTTGG CCGTGTACTA CAGGGGAGGA 
GCTTTGCTAA CGAGCCCCAG TGGACCAGGC TATCATATCA TGTTGCCTTT CATTACAACA 
TTCAGATCTG TGCAGACAAC ACTACAAACG GATGAAGTTA AAAATGTGCC TTGTGGAACA 
AGTGGTGGAG TCATGATCTA TATTGACCGA ATAGAAGTGG TTAATATGTT GGCTCCTTAT 
GCAGTGTTTG ACATTGTGAG GAACTATACT GCAGACTACG ACAAGACTTT AATCTTCAAT 
AAAATCCACC ATGAGCTGAA CCAGTTTTGC AGTGCCCACA CACTTCAAGA AGTTTACATA 
GAATTGTTTG ATCAAATAGA TGAAAACCTG AAGCAGGCCC TGCAAAAAGA TTTAAACACC 
ATGGCCCCAG GTCTCACTAT CCAGGCTGTG CGTGTTACAA AACCCAAAAT CCCAGAAGCC 
ATAAGAAGAA ATTTTGAATT AATGGAGGCA GAGAAGACAA AACTTCTCAT AGCTGCACAG 
AAACAAAAGG TGGTGGAGAA AGAAGCTGAG ACGGAGAGGA AAAGGGCTGT TATAGAAGCA 
GAGAAGATTG CACAAGTAGC AAAAATTCGA TTTCAACAGA AAGTGATGGA GAAAGAAACT 
GAAAAACGCA TTTCTGAGAT TGAAGATGCT GCGTTCCTGG CCCGAGAGAA GGCAAAAGCA 
GATGCCGAGT ATTACGCTGC ACACAAATAC GCCACCTCAA ACAAGCACAA ACTGACCCCA 
GAGTATCTGG AGCTCAAGAA ATACCAGGCC ATTGCCTCAA ACAGTAAGAT CTACTTTGGC 
AGCAACATCC CCAGCATGTT TGTGGACTCC TCCTGTGCTC TGAAATACTC TGATGGTAGG 
ACTGGGAGAG AAGACTCCCT TCCCCCAGAG GAGGCCCGTG AGCCCTCTGG AGAGAGCCCC 
ATCCAAAACA AGGAGAACGC AGGTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006527061.1
CDS733..1779
Translation

Target ORF information:

RefSeq Version XM_006526998.3
Organism Mus musculus(house mouse)
Definition Mus musculus ER lipid raft associated 1 (Erlin1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006526998.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGAATATGA CTCAAGCCCG GCTTCTGGTG GCTGCAGTGG TGGGGTTGGT GGCGATCCTC 
CTGTACGCCT CCATCCACAA GATCGAAGAG GGACACTTGG CCGTGTACTA CAGGGGAGGA 
GCTTTGCTAA CGAGCCCCAG TGGACCAGGC TATCATATCA TGTTGCCTTT CATTACAACA 
TTCAGATCTG TGCAGACAAC ACTACAAACG GATGAAGTTA AAAATGTGCC TTGTGGAACA 
AGTGGTGGAG TCATGATCTA TATTGACCGA ATAGAAGTGG TTAATATGTT GGCTCCTTAT 
GCAGTGTTTG ACATTGTGAG GAACTATACT GCAGACTACG ACAAGACTTT AATCTTCAAT 
AAAATCCACC ATGAGCTGAA CCAGTTTTGC AGTGCCCACA CACTTCAAGA AGTTTACATA 
GAATTGTTTG ATCAAATAGA TGAAAACCTG AAGCAGGCCC TGCAAAAAGA TTTAAACACC 
ATGGCCCCAG GTCTCACTAT CCAGGCTGTG CGTGTTACAA AACCCAAAAT CCCAGAAGCC 
ATAAGAAGAA ATTTTGAATT AATGGAGGCA GAGAAGACAA AACTTCTCAT AGCTGCACAG 
AAACAAAAGG TGGTGGAGAA AGAAGCTGAG ACGGAGAGGA AAAGGGCTGT TATAGAAGCA 
GAGAAGATTG CACAAGTAGC AAAAATTCGA TTTCAACAGA AAGTGATGGA GAAAGAAACT 
GAAAAACGCA TTTCTGAGAT TGAAGATGCT GCGTTCCTGG CCCGAGAGAA GGCAAAAGCA 
GATGCCGAGT ATTACGCTGC ACACAAATAC GCCACCTCAA ACAAGCACAA ACTGACCCCA 
GAGTATCTGG AGCTCAAGAA ATACCAGGCC ATTGCCTCAA ACAGTAAGAT CTACTTTGGC 
AGCAACATCC CCAGCATGTT TGTGGACTCC TCCTGTGCTC TGAAATACTC TGATGGTAGG 
ACTGGGAGAG AAGACTCCCT TCCCCCAGAG GAGGCCCGTG AGCCCTCTGG AGAGAGCCCC 
ATCCAAAACA AGGAGAACGC AGGTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu22596
Clone ID Related Accession (Same CDS sequence) NM_001164360.1 , NM_145502.3 , XM_006526998.3 , NM_001164359.1 , XM_006526998.4
Accession Version XM_006526998.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1047bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product erlin-1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006526998.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGAATATGA CTCAAGCCCG GCTTCTGGTG GCTGCAGTGG TGGGGTTGGT GGCGATCCTC 
CTGTACGCCT CCATCCACAA GATCGAAGAG GGACACTTGG CCGTGTACTA CAGGGGAGGA 
GCTTTGCTAA CGAGCCCCAG TGGACCAGGC TATCATATCA TGTTGCCTTT CATTACAACA 
TTCAGATCTG TGCAGACAAC ACTACAAACG GATGAAGTTA AAAATGTGCC TTGTGGAACA 
AGTGGTGGAG TCATGATCTA TATTGACCGA ATAGAAGTGG TTAATATGTT GGCTCCTTAT 
GCAGTGTTTG ACATTGTGAG GAACTATACT GCAGACTACG ACAAGACTTT AATCTTCAAT 
AAAATCCACC ATGAGCTGAA CCAGTTTTGC AGTGCCCACA CACTTCAAGA AGTTTACATA 
GAATTGTTTG ATCAAATAGA TGAAAACCTG AAGCAGGCCC TGCAAAAAGA TTTAAACACC 
ATGGCCCCAG GTCTCACTAT CCAGGCTGTG CGTGTTACAA AACCCAAAAT CCCAGAAGCC 
ATAAGAAGAA ATTTTGAATT AATGGAGGCA GAGAAGACAA AACTTCTCAT AGCTGCACAG 
AAACAAAAGG TGGTGGAGAA AGAAGCTGAG ACGGAGAGGA AAAGGGCTGT TATAGAAGCA 
GAGAAGATTG CACAAGTAGC AAAAATTCGA TTTCAACAGA AAGTGATGGA GAAAGAAACT 
GAAAAACGCA TTTCTGAGAT TGAAGATGCT GCGTTCCTGG CCCGAGAGAA GGCAAAAGCA 
GATGCCGAGT ATTACGCTGC ACACAAATAC GCCACCTCAA ACAAGCACAA ACTGACCCCA 
GAGTATCTGG AGCTCAAGAA ATACCAGGCC ATTGCCTCAA ACAGTAAGAT CTACTTTGGC 
AGCAACATCC CCAGCATGTT TGTGGACTCC TCCTGTGCTC TGAAATACTC TGATGGTAGG 
ACTGGGAGAG AAGACTCCCT TCCCCCAGAG GAGGCCCGTG AGCCCTCTGG AGAGAGCCCC 
ATCCAAAACA AGGAGAACGC AGGTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006527061.1
CDS403..1449
Translation

Target ORF information:

RefSeq Version XM_006526998.4
Organism Mus musculus(house mouse)
Definition Mus musculus ER lipid raft associated 1 (Erlin1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006526998.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGAATATGA CTCAAGCCCG GCTTCTGGTG GCTGCAGTGG TGGGGTTGGT GGCGATCCTC 
CTGTACGCCT CCATCCACAA GATCGAAGAG GGACACTTGG CCGTGTACTA CAGGGGAGGA 
GCTTTGCTAA CGAGCCCCAG TGGACCAGGC TATCATATCA TGTTGCCTTT CATTACAACA 
TTCAGATCTG TGCAGACAAC ACTACAAACG GATGAAGTTA AAAATGTGCC TTGTGGAACA 
AGTGGTGGAG TCATGATCTA TATTGACCGA ATAGAAGTGG TTAATATGTT GGCTCCTTAT 
GCAGTGTTTG ACATTGTGAG GAACTATACT GCAGACTACG ACAAGACTTT AATCTTCAAT 
AAAATCCACC ATGAGCTGAA CCAGTTTTGC AGTGCCCACA CACTTCAAGA AGTTTACATA 
GAATTGTTTG ATCAAATAGA TGAAAACCTG AAGCAGGCCC TGCAAAAAGA TTTAAACACC 
ATGGCCCCAG GTCTCACTAT CCAGGCTGTG CGTGTTACAA AACCCAAAAT CCCAGAAGCC 
ATAAGAAGAA ATTTTGAATT AATGGAGGCA GAGAAGACAA AACTTCTCAT AGCTGCACAG 
AAACAAAAGG TGGTGGAGAA AGAAGCTGAG ACGGAGAGGA AAAGGGCTGT TATAGAAGCA 
GAGAAGATTG CACAAGTAGC AAAAATTCGA TTTCAACAGA AAGTGATGGA GAAAGAAACT 
GAAAAACGCA TTTCTGAGAT TGAAGATGCT GCGTTCCTGG CCCGAGAGAA GGCAAAAGCA 
GATGCCGAGT ATTACGCTGC ACACAAATAC GCCACCTCAA ACAAGCACAA ACTGACCCCA 
GAGTATCTGG AGCTCAAGAA ATACCAGGCC ATTGCCTCAA ACAGTAAGAT CTACTTTGGC 
AGCAACATCC CCAGCATGTT TGTGGACTCC TCCTGTGCTC TGAAATACTC TGATGGTAGG 
ACTGGGAGAG AAGACTCCCT TCCCCCAGAG GAGGCCCGTG AGCCCTCTGG AGAGAGCCCC 
ATCCAAAACA AGGAGAACGC AGGTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis.
The Journal of cell biology203(3)427-36(2013 Nov)
Huber MD,Vesely PW,Datta K,Gerace L


book

Clustered hydrophobic amino acids in amphipathic helices mediate erlin1/2 complex assembly.
Biochemical and biophysical research communications415(1)135-40(2011 Nov)
Pednekar D,Wang Y,Fedotova TV,Wojcikiewicz RJ


book

An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors.
The Journal of biological chemistry284(16)10433-45(2009 Apr)
Pearce MM,Wormer DB,Wilkens S,Wojcikiewicz RJ


book

Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.
The Journal of biological chemistry283(27)18792-800(2008 Jul)
Lyssand JS,DeFino MC,Tang XB,Hertz AL,Feller DB,Wacker JL,Adams ME,Hague C