Gene Symbol | Dyrk3 |
Entrez Gene ID | 226419 |
Full Name | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
Synonyms | BC006704 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Dyrk3 cDNA ORF clone
Gene Symbol | Dyrk3 |
Entrez Gene ID | 226419 |
Full Name | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
Synonyms | BC006704 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_145508.2 | NP_663483.1 | dual specificity tyrosine-phosphorylation-regulated kinase 3 |
XM_006529427.3 | XP_006529490.1 | dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X1 |
XM_006529427.2 | XP_006529490.1 | dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X1 |
Gallus gallus (chicken) | DYRK3 | XP_003642771.1 |
Xenopus tropicalis (tropical clawed frog) | dyrk3 | NP_001008158.1 |
Canis lupus familiaris (dog) | DYRK3 | XP_003434997.2 |
Bos taurus (cattle) | DYRK3 | NP_001093768.1 |
Danio rerio (zebrafish) | zgc:172180 | NP_001108400.1 |
Homo sapiens (human) | DYRK3 | NP_003573.2 |
Pan troglodytes (chimpanzee) | DYRK3 | XP_524527.2 |
DYRK3 | XP_001086117.1 | |
Mus musculus (house mouse) | Dyrk3 | NP_663483.1 |
Rattus norvegicus (Norway rat) | Dyrk3 | NP_001019938.1 |
Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling.
Wippich F, Bodenmiller B, Trajkovska MG, Wanka S, Aebersold R, Pelkmans L
Cell152(4)791-805(2013 Feb)
DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.
Guo X, Williams JG, Schug TT, Li X
The Journal of biological chemistry285(17)13223-32(2010 Apr)
DYRK3 dual-specificity kinase attenuates erythropoiesis during anemia.
Bogacheva O, Bogachev O, Menon M, Dev A, Houde E, Valoret EI, Prosser HM, Creasy CL, Pickering SJ, Grau E, Rance K, Livi GP, Karur V, Erickson-Miller CL, Wojchowski DM
The Journal of biological chemistry283(52)36665-75(2008 Dec)
Erythropoietin-dependent erythropoiesis: New insights and questions.
Wojchowski DM, Menon MP, Sathyanarayana P, Fang J, Karur V, Houde E, Kapelle W, Bogachev O
Blood cells, molecules & diseases36(2)232-8(2006 Mar-Apr)
DYRK gene structure and erythroid-restricted features of DYRK3 gene expression.
Zhang D, Li K, Erickson-Miller CL, Weiss M, Wojchowski DM
Genomics85(1)117-30(2005 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Study identified the dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3) as a protein with the ability to condense P-granule-like speckles in the cytosol and to prevent stress granule dissolution via its N-terminal domain when it is in a kinase-inactive form.
Title: Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling.
DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.
Title: DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.
DYRK3 dual-specificity kinase attenuates erythropoiesis during anemia
Title: DYRK3 dual-specificity kinase attenuates erythropoiesis during anemia.
DYRK3, expression is strong in erythroid cells and testis, but is also detected in adult kidney and liver
Title: DYRK gene structure and erythroid-restricted features of DYRK3 gene expression.
The following Dyrk3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dyrk3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu28122 | |
Clone ID Related Accession (Same CDS sequence) | XM_006529427.3 , XM_006529427.2 | |
Accession Version | XM_006529427.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006529427.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGATAG ATGAAACCAA GGGCCCACCC TATTCGGACA CATTCAGCAA CCCCTCTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006529490.1 |
CDS | 100..1755 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006529427.2 |
1 | ATGATGATAG ATGAAACCAA GGGCCCACCC TATTCGGACA CATTCAGCAA CCCCTCTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu28122 | |
Clone ID Related Accession (Same CDS sequence) | XM_006529427.3 , XM_006529427.2 | |
Accession Version | XM_006529427.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006529427.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGATAG ATGAAACCAA GGGCCCACCC TATTCGGACA CATTCAGCAA CCCCTCTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006529490.1 |
CDS | 172..1827 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006529427.3 |
1 | ATGATGATAG ATGAAACCAA GGGCCCACCC TATTCGGACA CATTCAGCAA CCCCTCTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu11701 | |
Clone ID Related Accession (Same CDS sequence) | NM_145508.2 | |
Accession Version | NM_145508.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1761bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-05 | |
Organism | Mus musculus(house mouse) | |
Product | dual specificity tyrosine-phosphorylation-regulated kinase 3 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL513351.26. On Nov 17, 2006 this sequence version replaced NM_145508.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC006704.1, AK161495.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164141 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGAGGCG CAGCCCGCGA TCGCGGGAGG AAGGACGCGG CGCTGCCGGG GGCCGGGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_663483.1 |
CDS | 79..1839 |
Translation |
Target ORF information:
Target ORF information:
|
NM_145508.2 |
1 | ATGGGAGGCG CAGCCCGCGA TCGCGGGAGG AAGGACGCGG CGCTGCCGGG GGCCGGGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling. |
DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1. |
DYRK3 dual-specificity kinase attenuates erythropoiesis during anemia. |
Erythropoietin-dependent erythropoiesis: New insights and questions. |
DYRK gene structure and erythroid-restricted features of DYRK3 gene expression. |