Gene Symbol | Arhgef4 |
Entrez Gene ID | 226970 |
Full Name | Rho guanine nucleotide exchange factor (GEF) 4 |
Synonyms | 9330140K16Rik,Asef |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Arhgef4 cDNA ORF clone
Gene Symbol | Arhgef4 |
Entrez Gene ID | 226970 |
Full Name | Rho guanine nucleotide exchange factor (GEF) 4 |
Synonyms | 9330140K16Rik,Asef |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_030253601.1 | XP_030109461.1 | rho guanine nucleotide exchange factor 4 isoform X1 |
XM_030253611.1 | XP_030109471.1 | rho guanine nucleotide exchange factor 4 isoform X6 |
NM_183019.3 | NP_898840.2 | rho guanine nucleotide exchange factor 4 isoform 2 |
NM_001368773.1 | NP_001355702.1 | rho guanine nucleotide exchange factor 4 isoform 1 |
NM_183019.2 | NP_898840.2 | rho guanine nucleotide exchange factor 4 |
XM_030253613.1 | XP_030109473.1 | rho guanine nucleotide exchange factor 4 isoform X7 |
XM_030253609.1 | XP_030109469.1 | rho guanine nucleotide exchange factor 4 isoform X5 |
XM_030253603.1 | XP_030109463.1 | rho guanine nucleotide exchange factor 4 isoform X2 |
XM_030253604.1 | XP_030109464.1 | rho guanine nucleotide exchange factor 4 isoform X3 |
XM_030253606.1 | XP_030109466.1 | rho guanine nucleotide exchange factor 4 isoform X4 |
XM_030253614.1 | XP_030109474.1 | rho guanine nucleotide exchange factor 4 isoform X8 |
Homo sapiens (human) | ARHGEF4 | NP_056135.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100487089 | XP_004917856.1 |
Bos taurus (cattle) | ARHGEF4 | NP_001179002.1 |
Rattus norvegicus (Norway rat) | Arhgef4 | XP_006244788.1 |
Danio rerio (zebrafish) | arhgef4 | XP_687404.3 |
Pan troglodytes (chimpanzee) | ARHGEF4 | XP_525919.2 |
Mus musculus (house mouse) | Arhgef4 | NP_898840.2 |
LOC703647 | XP_002808100.1 | |
Canis lupus familiaris (dog) | LOC483856 | XP_540976.4 |
Gallus gallus (chicken) | ARHGEF4 | XP_004937023.1 |
Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury.
Chaboub LS, Manalo JM, Lee HK, Glasgow SM, Chen F, Kawasaki Y, Akiyama T, Kuo CT, Creighton CJ, Mohila CA, Deneen B
The Journal of neuroscience : the official journal of the Society for Neuroscience36(47)11904-11917(2016 Nov)
Asef mediates HGF protective effects against LPS-induced lung injury and endothelial barrier dysfunction.
Meng F, Meliton A, Moldobaeva N, Mutlu G, Kawasaki Y, Akiyama T, Birukova AA
American journal of physiology. Lung cellular and molecular physiology308(5)L452-63(2015 Mar)
Asef controls vascular endothelial permeability and barrier recovery in the lung.
Tian X, Tian Y, Gawlak G, Meng F, Kawasaki Y, Akiyama T, Birukova AA
Molecular biology of the cell26(4)636-50(2015 Feb)
Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis.
Kang P, Lee HK, Glasgow SM, Finley M, Donti T, Gaber ZB, Graham BH, Foster AE, Novitch BG, Gronostajski RM, Deneen B
Neuron74(1)79-94(2012 Apr)
The adenomatous polyposis coli-associated guanine nucleotide exchange factor Asef is involved in angiogenesis.
Kawasaki Y, Jigami T, Furukawa S, Sagara M, Echizen K, Shibata Y, Sato R, Akiyama T
The Journal of biological chemistry285(2)1199-207(2010 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
these results demonstrate potent anti-inflammatory effects by HGF and delineate a key role of Asef in the mediation of the HGF barrier protective and anti-inflammatory effects.
Title: Asef mediates HGF protective effects against LPS-induced lung injury and endothelial barrier dysfunction.
Asef has a role in HGF-mediated protection against endothelial hyperpermeability and lung injury.
Title: Asef controls vascular endothelial permeability and barrier recovery in the lung.
Asef and Asef2 are required for adenoma formation in Apc(Min/+)mice.
Title: The adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in Apc(Min/+)mice.
The following Arhgef4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arhgef4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu08296 | |
Clone ID Related Accession (Same CDS sequence) | NM_183019.3 , NM_183019.2 | |
Accession Version | NM_183019.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1455bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-25 | |
Organism | Mus musculus(house mouse) | |
Product | rho guanine nucleotide exchange factor 4 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC107738.16. On Feb 25, 2019 this sequence version replaced NM_183019.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.188481.1, SRR7345562.746938.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGATGACC AGGAGCTGGG CTTCAAAGCT GGGGATGTCA TCGAAGTGAT GGATGCCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_898840.2 |
CDS | 316..1770 |
Translation |
Target ORF information:
Target ORF information:
|
NM_183019.3 |
1 | ATGGATGACC AGGAGCTGGG CTTCAAAGCT GGGGATGTCA TCGAAGTGAT GGATGCCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu08296 | |
Clone ID Related Accession (Same CDS sequence) | NM_183019.3 , NM_183019.2 | |
Accession Version | NM_183019.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1455bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-22 | |
Organism | Mus musculus(house mouse) | |
Product | rho guanine nucleotide exchange factor 4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB609907.1, BC055804.1 and AK034013.1. On Dec 17, 2004 this sequence version replaced NM_183019.1. ##Evidence-Data-START## Transcript exon combination :: AK169957.1, AK163424.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGATGACC AGGAGCTGGG CTTCAAAGCT GGGGATGTCA TCGAAGTGAT GGATGCCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_898840.2 |
CDS | 335..1789 |
Translation |
Target ORF information:
Target ORF information:
|
NM_183019.2 |
1 | ATGGATGACC AGGAGCTGGG CTTCAAAGCT GGGGATGTCA TCGAAGTGAT GGATGCCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85142 | |
Clone ID Related Accession (Same CDS sequence) | XM_030253614.1 | |
Accession Version | XM_030253614.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1245bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | rho guanine nucleotide exchange factor 4 isoform X8 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATGACC AGGAGCTGGG CTTCAAAGCT GGGGATGTCA TCGAAGTGAT GGATGCCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030109474.1 |
CDS | 394..1638 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030253614.1 |
1 | ATGGATGACC AGGAGCTGGG CTTCAAAGCT GGGGATGTCA TCGAAGTGAT GGATGCCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85139 | |
Clone ID Related Accession (Same CDS sequence) | XM_030253609.1 | |
Accession Version | XM_030253609.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1932bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | rho guanine nucleotide exchange factor 4 isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCGGGGG ACCCGAAGCT ACGGCAGTGC GGCGGGGATG CTGCTGGCGA CCCCGCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030109469.1 |
CDS | 151..2082 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030253609.1 |
1 | ATGTCGGGGG ACCCGAAGCT ACGGCAGTGC GGCGGGGATG CTGCTGGCGA CCCCGCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85140 | |
Clone ID Related Accession (Same CDS sequence) | XM_030253611.1 | |
Accession Version | XM_030253611.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1833bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | rho guanine nucleotide exchange factor 4 isoform X6 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAAGGAC AAGAGCATGC TCTTCTGCCT TGCCCAGTGT CGTTCTCATC TGAAATGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030109471.1 |
CDS | 111..1943 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030253611.1 |
1 | ATGCAAGGAC AAGAGCATGC TCTTCTGCCT TGCCCAGTGT CGTTCTCATC TGAAATGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85141 | |
Clone ID Related Accession (Same CDS sequence) | XM_030253613.1 | |
Accession Version | XM_030253613.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1722bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | rho guanine nucleotide exchange factor 4 isoform X7 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCGGGGG ACCCGAAGCT ACGGCAGTGC GGCGGGGATG CTGCTGGCGA CCCCGCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030109473.1 |
CDS | 151..1872 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030253613.1 |
1 | ATGTCGGGGG ACCCGAAGCT ACGGCAGTGC GGCGGGGATG CTGCTGGCGA CCCCGCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu84554 | |
Clone ID Related Accession (Same CDS sequence) | NM_001368773.1 | |
Accession Version | NM_001368773.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5568bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-24 | |
Organism | Mus musculus(house mouse) | |
Product | rho guanine nucleotide exchange factor 4 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC157813.6, AC107766.14 and AC107738.16. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGCTCGGTG TGGTGCACTT CCTTCGCAGC TTCTTTAAGA CTCCAGAGCC AGGTGTGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001355702.1 |
CDS | 43..5610 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001368773.1 |
1 | ATGCTCGGTG TGGTGCACTT CCTTCGCAGC TTCTTTAAGA CTCCAGAGCC AGGTGTGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85135 | |
Clone ID Related Accession (Same CDS sequence) | XM_030253601.1 | |
Accession Version | XM_030253601.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5550bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | rho guanine nucleotide exchange factor 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATGTGC TGGATCTGGA GACTCCAGAG CCAGGTGTGC CCCCTCCAGG TGAGGAAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030109461.1 |
CDS | 114..5663 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030253601.1 |
1 | ATGGATGTGC TGGATCTGGA GACTCCAGAG CCAGGTGTGC CCCCTCCAGG TGAGGAAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85136 | |
Clone ID Related Accession (Same CDS sequence) | XM_030253603.1 | |
Accession Version | XM_030253603.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5358bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | rho guanine nucleotide exchange factor 4 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTCGGTG TGGTGCACTT CCTTCGCAGC TTCTTTAAGA CTCCAGAGCC AGGTGTGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030109463.1 |
CDS | 122..5479 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030253603.1 |
1 | ATGCTCGGTG TGGTGCACTT CCTTCGCAGC TTCTTTAAGA CTCCAGAGCC AGGTGTGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85137 | |
Clone ID Related Accession (Same CDS sequence) | XM_030253604.1 | |
Accession Version | XM_030253604.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5268bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | rho guanine nucleotide exchange factor 4 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTCGGTG TGGTGCACTT CCTTCGCAGC TTCTTTAAGA CTCCAGAGCC AGGTGTGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030109464.1 |
CDS | 122..5389 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030253604.1 |
1 | ATGCTCGGTG TGGTGCACTT CCTTCGCAGC TTCTTTAAGA CTCCAGAGCC AGGTGTGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85138 | |
Clone ID Related Accession (Same CDS sequence) | XM_030253606.1 | |
Accession Version | XM_030253606.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5151bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | rho guanine nucleotide exchange factor 4 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTGACTG CTGGAAGACG GGATGAAGCA TGCCCCTGCA GCCGTGTGGC TAGCTTTGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030109466.1 |
CDS | 545..5695 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030253606.1 |
1 | ATGTTGACTG CTGGAAGACG GGATGAAGCA TGCCCCTGCA GCCGTGTGGC TAGCTTTGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury. |
Asef mediates HGF protective effects against LPS-induced lung injury and endothelial barrier dysfunction. |
Asef controls vascular endothelial permeability and barrier recovery in the lung. |
Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis. |
The adenomatous polyposis coli-associated guanine nucleotide exchange factor Asef is involved in angiogenesis. |