Tbpl2 cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Tbpl2 |
| Entrez Gene ID | 227606 |
| Full Name | TATA box binding protein like 2 |
| Synonyms | Gm348,Trf3 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_199059.2 | NP_951014.1 | TATA box-binding protein-like protein 2 isoform 1 |
| NM_001289689.1 | NP_001276618.1 | TATA box-binding protein-like protein 2 isoform 2 |
| Pan troglodytes (chimpanzee) | TBPL2 | XP_003952543.1 |
| Bos taurus (cattle) | TBPL2 | XP_002690959.2 |
| Oryza sativa (rice) | Os03g0657000 | NP_001050812.1 |
| Arabidopsis thaliana (thale cress) | TBP2 | NP_849812.1 |
| Arabidopsis thaliana (thale cress) | TBP1 | NP_187953.1 |
| Mus musculus (house mouse) | Tbpl2 | NP_951014.1 |
| Gallus gallus (chicken) | TBPL2 | NP_001092323.1 |
| Xenopus tropicalis (tropical clawed frog) | tbpl2 | NP_001017309.1 |
| Homo sapiens (human) | TBPL2 | NP_950248.1 |
| Canis lupus familiaris (dog) | TBPL2 | XP_005623974.1 |
| Rattus norvegicus (Norway rat) | Tbpl2 | NP_001092831.1 |
| Oryza sativa (rice) | Os12g0580300 | NP_001067128.1 |
| LOC697371 | XP_001088740.1 | |
| Danio rerio (zebrafish) | tbpl2 | NP_999961.1 |
Related articles in PubMed
TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells.
Malecova B, Dall'Agnese A, Madaro L, Gatto S, Coutinho Toto P, Albini S, Ryan T, Tora L, Puri PL
eLife5(2016 Feb)
Selective interaction between Trf3 and Taf3 required for early development and hematopoiesis.
Hart DO, Santra MK, Raha T, Green MR
Developmental dynamics : an official publication of the American Association of Anatomists238(10)2540-9(2009 Oct)
TBP2 is essential for germ cell development by regulating transcription and chromatin condensation in the oocyte.
Gazdag E, Santenard A, Ziegler-Birling C, Altobelli G, Poch O, Tora L, Torres-Padilla ME
Genes & development23(18)2210-23(2009 Sep)
MyoD targets TAF3/TRF3 to activate myogenin transcription.
Deato MD, Marr MT, Sottero T, Inouye C, Hu P, Tjian R
Molecular cell32(1)96-105(2008 Oct)
Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.
Tatarakis A, Margaritis T, Martinez-Jimenez CP, Kouskouti A, Mohan WS 2nd, Haroniti A, Kafetzopoulos D, Tora L, Talianidis I
Molecular cell31(4)531-43(2008 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
TBP2 binds to promoters of misregulated genes, suggesting that TBP2 directly regulates their expression
Title: TBP2 is essential for germ cell development by regulating transcription and chromatin condensation in the oocyte.
properties of a TAF3/TRF3 complex in directing transcription initiation at the Myogenin promoter
Title: MyoD targets TAF3/TRF3 to activate myogenin transcription.
Data suggest that TRF3 plays a role in early mouse development, and may also be involved in Pol I transcription.
Title: Regulated expression of TATA-binding protein-related factor 3 (TRF3) during early embryogenesis.
TRF3 is a nuclear protein that is present in all human and mouse tissues and cell lines examined
Title: TRF3, a TATA-box-binding protein-related factor, is vertebrate-specific and widely expressed.
The following Tbpl2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tbpl2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu58065 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001289689.1 | |
| Accession Version | NM_001289689.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1050bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-11 | |
| Organism | Mus musculus(house mouse) | |
| Product | TATA box-binding protein-like protein 2 isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL844838.7. On Jan 25, 2014 this sequence version replaced XM_006497859.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes isoform 2, which is shorter by an amino acid, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC100305.1, BC144904.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGTGGGCT CTCTCATCAT GGAGGAGGAC ATATACCTGG ACCTCTTCCT GGATCCTTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001276618.1 |
| CDS | 61..1110 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001289689.1 |
ORF Insert Sequence:
1 | ATGGTGGGCT CTCTCATCAT GGAGGAGGAC ATATACCTGG ACCTCTTCCT GGATCCTTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu58053 | |
| Clone ID Related Accession (Same CDS sequence) | NM_199059.2 | |
| Accession Version | NM_199059.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-11 | |
| Organism | Mus musculus(house mouse) | |
| Product | TATA box-binding protein-like protein 2 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL844838.7. On Jan 25, 2014 this sequence version replaced NM_199059.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY457924.1, BC119160.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGTGGGCT CTCTCATCAT GGAGGAGGAC ATATACCTGG ACCTCTTCCT GGATCCTTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_951014.1 |
| CDS | 61..1113 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_199059.2 |
ORF Insert Sequence:
1 | ATGGTGGGCT CTCTCATCAT GGAGGAGGAC ATATACCTGG ACCTCTTCCT GGATCCTTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells. |
|
Selective interaction between Trf3 and Taf3 required for early development and hematopoiesis. |
|
TBP2 is essential for germ cell development by regulating transcription and chromatin condensation in the oocyte. |
|
MyoD targets TAF3/TRF3 to activate myogenin transcription. |
|
Dominant and redundant functions of TFIID involved in the regulation of hepatic genes. |