Tmprss11d cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tmprss11d
Entrez Gene ID	231382
Full Name	transmembrane protease, serine 11d
Synonyms	AST,AsP,BC020151
General protein information	Preferred Names transmembrane protease, serine 11d Names transmembrane protease serine 11D AT adrenal secretory serine protease airway spesific trypsin-like protease airway trypsin-like protease
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 E1

mRNA and Protein(s)

mRNA	Protein	Name
NM_145561.2	NP_663536.1	transmembrane protease serine 11D

Pathways from BioSystems

Homologies

Homo sapiens (human)	TMPRSS11D	NP_004253.1
	TMPRSS11D	XP_001109114.1
Canis lupus familiaris (dog)	TMPRSS11D	XP_854470.1
Bos taurus (cattle)	TMPRSS11D	XP_002688359.1
Rattus norvegicus (Norway rat)	Tmprss11d	NP_001028824.1
Anopheles gambiae (African malaria mosquito)	TRY1_ANOGA	XP_317170.2
Anopheles gambiae (African malaria mosquito)	TRY4_ANOGA	XP_317173.2
Pan troglodytes (chimpanzee)	TMPRSS11D	XP_526607.2
Anopheles gambiae (African malaria mosquito)	TRY6_ANOGA	XP_317175.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012842	XP_001230353.1
Anopheles gambiae (African malaria mosquito)	TRY7_ANOGA	XP_317172.2
Mus musculus (house mouse)	Tmprss11d	NP_663536.1
Anopheles gambiae (African malaria mosquito)	TRY5_ANOGA	XP_317174.2
Anopheles gambiae (African malaria mosquito)	TRY3_ANOGA	XP_317171.2
Anopheles gambiae (African malaria mosquito)	TRY2_ANOGA	XP_555167.1

Gene Ontology
Bibliography

Related articles in PubMed

TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein.
Heurich A, Hofmann-Winkler H, Gierer S, Liepold T, Jahn O, P?hlmann S
Journal of virology88(2)1293-307(2014 Jan)

Expression and genetic loss of function analysis of the HAT/DESC cluster proteases TMPRSS11A and HAT.
Sales KU, Hobson JP, Wagenaar-Miller R, Szabo R, Rasmussen AL, Bey A, Shah MF, Molinolo AA, Bugge TH
PloS one6(8)e23261(2011)

Expression and spatio-temporal distribution of differentiation and proliferation markers during mouse adrenal development.
Schulte DM, Shapiro I, Reincke M, Beuschlein F
Gene expression patterns : GEP7(1-2)72-81(2007 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A comprehensive phenotypic analysis of mice deficient in two of the most widely expressed HAT/DESC proteases, TMPRSS11A and HAT, was performed.
Title: Expression and genetic loss of function analysis of the HAT/DESC cluster proteases TMPRSS11A and HAT.

Predominantly expressed in upper gastrointestinal and respiratory tract-but also in adrenal gland. Complex expression pattern. Multifunctional role beyond adrenal proliferation.
Title: The adrenal secretory serine protease AsP is a short secretory isoform of the transmembrane airway trypsin-like protease.

The following Tmprss11d gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmprss11d cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu20166	NM_145561.2 Latest version!	Mus musculus transmembrane protease, serine 11d (Tmprss11d), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tmprss11d ( NM_145561.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_663536.1 Mus musculus transmembrane protease, serine 11d (Tmprss11d), mRNA.

Price & Availability↑

CloneID	OMu20166
Clone ID Related Accession (Same CDS sequence)	NM_145561.2
Accession Version	NM_145561.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1254bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-28
Organism	Mus musculus(house mouse)
Product	transmembrane protease serine 11D
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC098885.3 and AC100746.4. On Nov 17, 2006 this sequence version replaced NM_145561.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC020151.1, AB053953.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849376 [ECO:0000350] ##Evidence-Data-END##

ATGTATAGGC CAAGACCAAT GCTATCACCG TCAAGATTCT TCACTCCCTT TGCAGTAGCT 
TTCGTTGTCA TAATAACGGT AGGGCTCCTG GCCATGATGG CAGGTCTACT TATTCACTTT 
TTAGCTTTTG ACAAGAAAGC TTACTTTTAT CATAGCAGCT TTCAAATCCT AAACGTTGAA 
TACACTGAGG CTTTAAACTC ACCAGCTACA CACGAATACA GAACCTTGAG TGAAAGAATT 
GAGGCTATGA TTACTGATGA ATTTCGAGGA TCAAGTCTAA AAAGTGAGTT TATCAGGACA 
CATGTTGTCA AACTAAGAAA AGAAGGGACT GGTGTGGTTG CGGATGTTGT CATGAAATTT 
CGATCTAGTA AACGTAACAA CAGAAAGGTA ATGAAAACCA GAATTCAATC TGTGCTACGA 
AGACTCAGCA GCTCTGGAAA CTTGGAAATA GCCCCTTCGA ATGAGATAAC ATCACTCACT 
GACCAGGATA CAGAAAATGT TTTGACTCAA GAATGTGGAG CACGTCCAGA CCTTATAACA 
CTGTCAGAAG AGAGAATCAT TGGAGGCATG CAAGCTGAGC CCGGTGACTG GCCCTGGCAA 
GTCAGTCTAC AGCTCAATAA TGTCCACCAC TGTGGAGGTG CCCTGATCAG TAACATGTGG 
GTCCTGACAG CAGCTCATTG CTTCAAAAGC TATCCTAATC CTCAATATTG GACAGCCACC 
TTTGGGGTTT CTACAATGAG CCCTAGGCTG AGAGTGAGAG TAAGGGCTAT TTTAGCCCAC 
GACGGGTACA GCTCCGTAAC TCGTGACAAT GACATCGCAG TTGTACAACT TGACAGATCT 
GTCGCCTTTT CCAGAAATAT CCATAGGGTA TGTCTCCCAG CAGCAACCCA AAATATCATC 
CCTGGTTCTG TCGCATATGT TACAGGATGG GGATCTCTCA CATATGGAGG CAACGCAGTC 
ACAAATCTAC GGCAAGGAGA GGTCAGAATA ATAAGTTCAG AGGAATGCAA TACGCCAGCT 
GGTTACAGTG GAAGTGTCTT GCCAGGAATG CTGTGTGCTG GAATGCGTTC AGGGGCCGTG 
GATGCATGCC AGGGTGATTC AGGTGGCCCG CTAGTACAAG AAGACTCAAG GCGGCTTTGG 
TTTGTTGTGG GCATTGTGAG CTGGGGATAT CAGTGTGGCC TCCCAAATAA GCCAGGCGTG 
TATACTCGAG TGACAGCCTA CCGCAACTGG ATCAGACAGC AGACGGGAAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_663536.1
CDS	36..1289
Translation	MYRPRPMLSPSRFFTPFAVAFVVIITVGLLAMMAGLLIHFLAFDKKAYFYHSSFQILNVEYTEALNSPATHEYRTLSERIEAMITDEFRGSSLKSEFIRTHVVKLRKEGTGVVADVVMKFRSSKRNNRKVMKTRIQSVLRRLSSSGNLEIAPSNEITSLTDQDTENVLTQECGARPDLITLSEERIIGGMQAEPGDWPWQVSLQLNNVHHCGGALISNMWVLTAAHCFKSYPNPQYWTATFGVSTMSPRLRVRVRAILAHDGYSSVTRDNDIAVVQLDRSVAFSRNIHRVCLPAATQNIIPGSVAYVTGWGSLTYGGNAVTNLRQGEVRIISSEECNTPAGYSGSVLPGMLCAGMRSGAVDACQGDSGGPLVQEDSRRLWFVVGIVSWGYQCGLPNKPGVYTRVTAYRNWIRQQTGI

Target ORF information:

RefSeq Version	NM_145561.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane protease, serine 11d (Tmprss11d), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145561.2

ORF Insert Sequence:

ATGTATAGGC CAAGACCAAT GCTATCACCG TCAAGATTCT TCACTCCCTT TGCAGTAGCT 
TTCGTTGTCA TAATAACGGT AGGGCTCCTG GCCATGATGG CAGGTCTACT TATTCACTTT 
TTAGCTTTTG ACAAGAAAGC TTACTTTTAT CATAGCAGCT TTCAAATCCT AAACGTTGAA 
TACACTGAGG CTTTAAACTC ACCAGCTACA CACGAATACA GAACCTTGAG TGAAAGAATT 
GAGGCTATGA TTACTGATGA ATTTCGAGGA TCAAGTCTAA AAAGTGAGTT TATCAGGACA 
CATGTTGTCA AACTAAGAAA AGAAGGGACT GGTGTGGTTG CGGATGTTGT CATGAAATTT 
CGATCTAGTA AACGTAACAA CAGAAAGGTA ATGAAAACCA GAATTCAATC TGTGCTACGA 
AGACTCAGCA GCTCTGGAAA CTTGGAAATA GCCCCTTCGA ATGAGATAAC ATCACTCACT 
GACCAGGATA CAGAAAATGT TTTGACTCAA GAATGTGGAG CACGTCCAGA CCTTATAACA 
CTGTCAGAAG AGAGAATCAT TGGAGGCATG CAAGCTGAGC CCGGTGACTG GCCCTGGCAA 
GTCAGTCTAC AGCTCAATAA TGTCCACCAC TGTGGAGGTG CCCTGATCAG TAACATGTGG 
GTCCTGACAG CAGCTCATTG CTTCAAAAGC TATCCTAATC CTCAATATTG GACAGCCACC 
TTTGGGGTTT CTACAATGAG CCCTAGGCTG AGAGTGAGAG TAAGGGCTAT TTTAGCCCAC 
GACGGGTACA GCTCCGTAAC TCGTGACAAT GACATCGCAG TTGTACAACT TGACAGATCT 
GTCGCCTTTT CCAGAAATAT CCATAGGGTA TGTCTCCCAG CAGCAACCCA AAATATCATC 
CCTGGTTCTG TCGCATATGT TACAGGATGG GGATCTCTCA CATATGGAGG CAACGCAGTC 
ACAAATCTAC GGCAAGGAGA GGTCAGAATA ATAAGTTCAG AGGAATGCAA TACGCCAGCT 
GGTTACAGTG GAAGTGTCTT GCCAGGAATG CTGTGTGCTG GAATGCGTTC AGGGGCCGTG 
GATGCATGCC AGGGTGATTC AGGTGGCCCG CTAGTACAAG AAGACTCAAG GCGGCTTTGG 
TTTGTTGTGG GCATTGTGAG CTGGGGATAT CAGTGTGGCC TCCCAAATAA GCCAGGCGTG 
TATACTCGAG TGACAGCCTA CCGCAACTGG ATCAGACAGC AGACGGGAAT CTAG