Gene Symbol | Ffar3 |
Entrez Gene ID | 233080 |
Full Name | free fatty acid receptor 3 |
Synonyms | Gm478,Gpr41 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Ffar3 cDNA ORF clone
Gene Symbol | Ffar3 |
Entrez Gene ID | 233080 |
Full Name | free fatty acid receptor 3 |
Synonyms | Gm478,Gpr41 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001033316.2 | NP_001028488.1 | free fatty acid receptor 3 |
Canis lupus familiaris (dog) | FFAR3 | XP_005616768.1 |
Pan troglodytes (chimpanzee) | FFAR3 | XP_001159667.1 |
Bos taurus (cattle) | FFAR3 | NP_001138705.1 |
Homo sapiens (human) | FFAR3 | NP_005295.1 |
FFAR3 | XP_001094758.1 | |
Mus musculus (house mouse) | Ffar3 | NP_001028488.1 |
Rattus norvegicus (Norway rat) | Ffar3 | NP_001102382.1 |
Danio rerio (zebrafish) | LOC100333904 | XP_002665089.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100489919 | XP_002938262.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100489751 | XP_002938261.2 |
Xenopus tropicalis (tropical clawed frog) | LOC101735161 | XP_004920890.1 |
Maternal High Fiber Diet during Pregnancy and Lactation Influences Regulatory T Cell Differentiation in Offspring in Mice.
Nakajima A, Kaga N, Nakanishi Y, Ohno H, Miyamoto J, Kimura I, Hori S, Sasaki T, Hiramatsu K, Okumura K, Miyake S, Habu S, Watanabe S
Journal of immunology (Baltimore, Md. : 1950)199(10)3516-3524(2017 Nov)
Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41.
Natarajan N, Hori D, Flavahan S, Steppan J, Flavahan NA, Berkowitz DE, Pluznick JL
Physiological genomics48(11)826-834(2016 Nov)
GPR41 modulates insulin secretion and gene expression in pancreatic ?-cells and modifies metabolic homeostasis in fed and fasting states.
Veprik A, Laufer D, Weiss S, Rubins N, Walker MD
FASEB journal : official publication of the Federation of American Societies for Experimental Biology30(11)3860-3869(2016 11)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
the maternal microbiome influences Treg differentiation in the thymus of offspring through GPR41-mediated Aire expression
Title: Maternal High Fiber Diet during Pregnancy and Lactation Influences Regulatory T Cell Differentiation in Offspring in Mice.
that GPR41 and its ligands, short-chain fatty acids, may play an important role in the fine-tuning of insulin secretion in fed and fasting states
Title: GPR41 modulates insulin secretion and gene expression in pancreatic ?-cells and modifies metabolic homeostasis in fed and fasting states.
Results indicate that FFAR3 is expressed on postganglionic sympathetic and sensory neurons in both the autonomic and somatic peripheral nervous system
Title: Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia.
FFAR3 is expressed in pancreatic beta cells and mediates an inhibition of insulin secretion by coupling to Gi-type G proteins.
Title: Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes.
mediates beta cell glucose stimulated insulin secretion through Galphai/o sensitive pathway
Title: FFAR3 modulates insulin secretion and global gene expression in mouse islets.
The following Ffar3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ffar3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu12587 | |
Clone ID Related Accession (Same CDS sequence) | NM_001033316.2 | |
Accession Version | NM_001033316.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-23 | |
Organism | Mus musculus(house mouse) | |
Product | free fatty acid receptor 3 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK148616.1. On Apr 6, 2007 this sequence version replaced NM_001033316.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK148616.1, BY741744.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGGACAA GCTTCTTTCT TGGCAATTAC TGGCTTTTCT TTTCCGTCTA CCTGTTGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001028488.1 |
CDS | 62..1021 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001033316.2 |
1 | ATGGGGACAA GCTTCTTTCT TGGCAATTAC TGGCTTTTCT TTTCCGTCTA CCTGTTGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Maternal High Fiber Diet during Pregnancy and Lactation Influences Regulatory T Cell Differentiation in Offspring in Mice. |
Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41. |
GPR41 modulates insulin secretion and gene expression in pancreatic ?-cells and modifies metabolic homeostasis in fed and fasting states. |