Pdk3 cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Pdk3 |
| Entrez Gene ID | 236900 |
| Full Name | pyruvate dehydrogenase kinase, isoenzyme 3 |
| Synonyms | 2610001M10Rik,AI035637 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_145630.2 | NP_663605.1 | pyruvate dehydrogenase kinase, isozyme 3 |
| NM_145630.3 | NP_663605.1 | pyruvate dehydrogenase kinase, isozyme 3 |
| Bos taurus (cattle) | PDK3 | NP_001095404.1 |
| Mus musculus (house mouse) | Pdk3 | NP_663605.1 |
| Danio rerio (zebrafish) | pdk3a | XP_005162814.1 |
| Drosophila melanogaster (fruit fly) | Pdk | NP_001097240.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010276 | XP_319468.3 |
| Neurospora crassa | NCU06760 | XP_963532.2 |
| Pan troglodytes (chimpanzee) | PDK3 | XP_003317444.2 |
| PDK3 | XP_002808569.1 | |
| Rattus norvegicus (Norway rat) | Pdk3 | NP_001100051.1 |
| Caenorhabditis elegans (roundworm) | pdhk-2 | NP_498928.1 |
| Schizosaccharomyces pombe (fission yeast) | pkp1 | NP_593879.1 |
| Gallus gallus (chicken) | PDK3 | NP_001006259.1 |
| Eremothecium gossypii | AGOS_AER270W | NP_985127.2 |
| Magnaporthe oryzae (rice blast fungus) | MGG_07161 | XP_003715359.1 |
| Oryza sativa (rice) | Os07g0637300 | NP_001060401.1 |
| Canis lupus familiaris (dog) | PDK3 | XP_005641265.1 |
| Oryza sativa (rice) | Os03g0370000 | NP_001050196.1 |
| Homo sapiens (human) | PDK3 | NP_001135858.1 |
| Kluyveromyces lactis | KLLA0F27423g | XP_456300.1 |
| Arabidopsis thaliana (thale cress) | PDK | NP_187300.3 |
| Xenopus tropicalis (tropical clawed frog) | pdk3 | NP_001107154.1 |
Related articles in PubMed
Pathogenic mechanisms underlying X-linked Charcot-Marie-Tooth neuropathy (CMTX6) in patients with a pyruvate dehydrogenase kinase 3 mutation.
Perez-Siles G, Ly C, Grant A, Drew AP, Yiu EM, Ryan MM, Chuang DT, Tso SC, Nicholson GA, Kennerson ML
Neurobiology of disease94237-44(2016 Oct)
Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.
Duteil D, Tosic M, Lausecker F, Nenseth HZ, M?ller JM, Urban S, Willmann D, Petroll K, Messaddeq N, Arrigoni L, Manke T, Kornfeld JW, Br?ning JC, Zagoriy V, Meret M, Dengjel J, Kanouni T, Sch?le R
Cell reports17(4)1008-1021(2016 10)
Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Bowman CE, Zhao L, Hartung T, Wolfgang MJ
Molecular and cellular biology36(15)2089-104(2016 Aug)
Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.
Sakakibara I, Wurmser M, Dos Santos M, Santolini M, Ducommun S, Davaze R, Guernec A, Sakamoto K, Maire P
Skeletal muscle6(1)30(2016)
Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation.
Hou X, Zhang L, Han L, Ge J, Ma R, Zhang X, Moley K, Schedl T, Wang Q
Journal of cell science128(13)2319-29(2015 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These findings reveal that there are divergent roles of PDKs during oocyte maturation and indicate a new mechanism controlling meiotic structure.
Title: Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation.
The following Pdk3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pdk3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu16171 | |
| Clone ID Related Accession (Same CDS sequence) | NM_145630.2 , NM_145630.3 | |
| Accession Version | NM_145630.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1248bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-12-27 | |
| Organism | Mus musculus(house mouse) | |
| Product | pyruvate dehydrogenase kinase, isozyme 3 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL589652.13. On Nov 17, 2006 this sequence version replaced NM_145630.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC008126.1, AK088478.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164143 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## | |
1 | ATGCGGCTCT TCTACCGGCT GCTCAAGCAG CCGGTCCCCA AGCAGATCGA GCGCTACTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_663605.1 |
| CDS | 144..1391 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_145630.2 |
ORF Insert Sequence:
1 | ATGCGGCTCT TCTACCGGCT GCTCAAGCAG CCGGTCCCCA AGCAGATCGA GCGCTACTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu16171 | |
| Clone ID Related Accession (Same CDS sequence) | NM_145630.2 , NM_145630.3 | |
| Accession Version | NM_145630.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1248bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-14 | |
| Organism | Mus musculus(house mouse) | |
| Product | pyruvate dehydrogenase kinase, isozyme 3 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL589652.13. On Jul 27, 2018 this sequence version replaced NM_145630.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.3204835.1, BC008126.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164143 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGCGGCTCT TCTACCGGCT GCTCAAGCAG CCGGTCCCCA AGCAGATCGA GCGCTACTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_663605.1 |
| CDS | 199..1446 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_145630.3 |
ORF Insert Sequence:
1 | ATGCGGCTCT TCTACCGGCT GCTCAAGCAG CCGGTCCCCA AGCAGATCGA GCGCTACTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Pathogenic mechanisms underlying X-linked Charcot-Marie-Tooth neuropathy (CMTX6) in patients with a pyruvate dehydrogenase kinase 3 mutation. |
|
Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue. |
|
Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series. |
|
Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle. |
|
Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation. |