Il22ra2 cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Il22ra2 |
| Entrez Gene ID | 237310 |
| Full Name | interleukin 22 receptor, alpha 2 |
| Synonyms | CRF2-10,CRF2-s1,CRF2X,Il-22bp |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_178258.5 | NP_839989.2 | interleukin-22 receptor subunit alpha-2 precursor |
| Canis lupus familiaris (dog) | IL22RA2 | XP_003638820.1 |
| LOC711059 | XP_001099782.2 | |
| Rattus norvegicus (Norway rat) | Il22ra2 | NP_001003404.1 |
| Pan troglodytes (chimpanzee) | IL22RA2 | XP_001171428.1 |
| Mus musculus (house mouse) | Il22ra2 | NP_839989.2 |
| Gallus gallus (chicken) | IL22RA2 | XP_004935760.1 |
| Danio rerio (zebrafish) | crfb9 | NP_001038744.1 |
| Homo sapiens (human) | IL22RA2 | NP_443194.1 |
| Bos taurus (cattle) | IL22RA2 | XP_002690307.2 |
Related articles in PubMed
A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury.
Kleinschmidt D, Giannou AD, McGee HM, Kempski J, Steglich B, Huber FJ, Ernst TM, Shiri AM, Wegscheid C, Tasika E, H?bener P, Huber P, Bedke T, Steffens N, Agalioti T, Fuchs T, Noll J, Lotter H, Tiegs G, Lohse AW, Axelrod JH, Galun E, Flavell RA, Gagliani N, Huber S
Journal of immunology (Baltimore, Md. : 1950)199(12)4078-4090(2017 Dec)
Interleukin-22 level is negatively correlated with neutrophil recruitment in the lungs in a Pseudomonas aeruginosa pneumonia model.
Broquet A, Jacqueline C, Davieau M, Besbes A, Roquilly A, Martin J, Caillon J, Dumoutier L, Renauld JC, Heslan M, Josien R, Asehnoune K
Scientific reports7(1)11010(2017 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Il22bp-deficient mice were more susceptible to acute liver damage in models of acute liver damage induced by ischemia reperfusion and acetaminophen administration. IL-22BP plays a protective role in acute liver damage, via controlling IL-22-induced Cxcl10 expression.
Title: A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury.
IL-22BP promotes bacterial uptake into Peyer's patches by influencing follicle-associated epithelium gene expression and function.
Title: IL-22BP dictates characteristics of Peyer's patch follicle-associated epithelium for antigen uptake.
IL22RA2 KO displayed a less severe EAE course, less demyelination and less infiltration of immune cells in the CNS.
Title: The multiple sclerosis risk gene IL22RA2 contributes to a more severe murine autoimmune neuroinflammation.
the IL-22-IL-22BP axis critically regulates intestinal tissue repair and tumorigenesis in the colon
Title: IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine.
cloning and characterization; gene encodes a protein of 230 amino acids that share 67.1% amino-acid sequence identity with human IL-22 binding protein; upregulated by LPS stimulation in monocytes
Title: Cloning and characterization of mouse IL-22 binding protein.
The following Il22ra2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Il22ra2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu07196 | |
| Clone ID Related Accession (Same CDS sequence) | NM_178258.5 | |
| Accession Version | NM_178258.5 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Mus musculus(house mouse) | |
| Product | interleukin-22 receptor subunit alpha-2 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK138913.1. On Apr 6, 2007 this sequence version replaced NM_178258.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK138913.1, AJ555484.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGATGCCTA AGCATTGCCT TCTAGGTCTC CTCATCATAC TCTTGAGCAG TGCAACAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_839989.2 |
| CDS | 13..705 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_178258.5 |
ORF Insert Sequence:
1 | ATGATGCCTA AGCATTGCCT TCTAGGTCTC CTCATCATAC TCTTGAGCAG TGCAACAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury. |
|
Interleukin-22 level is negatively correlated with neutrophil recruitment in the lungs in a Pseudomonas aeruginosa pneumonia model. |