| Gene Symbol | Lrit3 |
| Entrez Gene ID | 242235 |
| Full Name | leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 |
| Synonyms | Gm421 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
gRNAs
The following Lrit3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lrit3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu09976 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001287224.1 , NM_001287224.2 | |
| Accession Version | NM_001287224.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2046bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-23 | |
| Organism | Mus musculus(house mouse) | |
| Product | leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC111097.10 and BB628321.1. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## | |
1 | ATGTGGCTCT CGGCCTGCCT GTGCCTTGTG CTTAGCTTCC TGGGAGGAGT GAACGGTACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001274153.1 |
| CDS | 1..2046 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001287224.1 |
1 | ATGTGGCTCT CGGCCTGCCT GTGCCTTGTG CTTAGCTTCC TGGGAGGAGT GAACGGTACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu09976 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001287224.1 , NM_001287224.2 | |
| Accession Version | NM_001287224.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2046bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-26 | |
| Organism | Mus musculus(house mouse) | |
| Product | leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC111097.10. On Jun 19, 2019 this sequence version replaced NM_001287224.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: KF954709.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length. | |
1 | ATGTGGCTCT CGGCCTGCCT GTGCCTTGTG CTTAGCTTCC TGGGAGGAGT GAACGGTACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001274153.1 |
| CDS | 107..2152 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001287224.2 |
1 | ATGTGGCTCT CGGCCTGCCT GTGCCTTGTG CTTAGCTTCC TGGGAGGAGT GAACGGTACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
LRIT3 Differentially Affects Connectivity and Synaptic Transmission of Cones to ON- and OFF-Bipolar Cells. |
A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects. |
LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation. |
Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. |
Lrit3 deficient mouse (nob6): a novel model of complete congenital stationary night blindness (cCSNB). |
