Gene Symbol | Wdfy2 |
Entrez Gene ID | 268752 |
Full Name | WD repeat and FYVE domain containing 2 |
Synonyms | 5830485M08,B130024L21Rik,ProF,ZFYVE22 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Wdfy2 cDNA ORF clone
gRNAs
Gene Symbol | Wdfy2 |
Entrez Gene ID | 268752 |
Full Name | WD repeat and FYVE domain containing 2 |
Synonyms | 5830485M08,B130024L21Rik,ProF,ZFYVE22 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_175546.4 | NP_780755.2 | WD repeat and FYVE domain-containing protein 2 |
XM_006519065.3 | XP_006519128.1 | WD repeat and FYVE domain-containing protein 2 isoform X3 |
XM_006519063.3 | XP_006519126.1 | WD repeat and FYVE domain-containing protein 2 isoform X1 |
XM_006519064.1 | XP_006519127.1 | WD repeat and FYVE domain-containing protein 2 isoform X2 |
XM_006519064.2 | XP_006519127.1 | WD repeat and FYVE domain-containing protein 2 isoform X1 |
XM_006519065.4 | XP_006519128.1 | WD repeat and FYVE domain-containing protein 2 isoform X2 |
Homo sapiens (human) | WDFY2 | NP_443182.1 |
Canis lupus familiaris (dog) | WDFY2 | XP_848495.3 |
Mus musculus (house mouse) | Wdfy2 | NP_780755.2 |
Rattus norvegicus (Norway rat) | Wdfy2 | NP_001100739.1 |
Danio rerio (zebrafish) | wdfy2 | NP_991308.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008932 | XP_319687.1 |
Xenopus tropicalis (tropical clawed frog) | wdfy2 | XP_002936770.1 |
Gallus gallus (chicken) | WDFY2 | NP_001073218.1 |
Pan troglodytes (chimpanzee) | WDFY2 | XP_001158979.1 |
Caenorhabditis elegans (roundworm) | wdfy-2 | NP_495983.1 |
LOC708929 | XP_001106117.2 | |
Drosophila melanogaster (fruit fly) | CG5168 | NP_609400.1 |
Akt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis.
Fritzius T, Moelling K
The EMBO journal27(9)1399-410(2008 May)
WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta.
Fritzius T, Frey AD, Schweneker M, Mayer D, Moelling K
The FEBS journal274(6)1552-66(2007 Mar)
A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda.
Fritzius T, Burkard G, Haas E, Heinrich J, Schweneker M, Bosse M, Zimmermann S, Frey AD, Caelers A, Bachmann AS, Moelling K
The Biochemical journal399(1)9-20(2006 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data show that ProF binds to Foxo1, a negative regulator of insulin action and adipogenesis, and facilitates the phosphorylation and thus inactivation of Foxo1 by Akt.
Title: Akt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis.
The ProF protein partially co-localizes with EEA1 on vesicular structures and binds to the protein kinases Akt and PKCzeta/lambda (protein kinase Czeta/lambda) via its WD-repeat propeller.
Title: A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda.
The following Wdfy2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Wdfy2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu50027 | |
Clone ID Related Accession (Same CDS sequence) | XM_006519063.3 | |
Accession Version | XM_006519063.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | WD repeat and FYVE domain-containing protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006519063.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGCGG AGATCCAGCC CCAGCCACTG ACCCGCAAGC CGATCCTGCT GCAGCGGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006519126.1 |
CDS | 104..1063 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCGGCGG AGATCCAGCC CCAGCCACTG ACCCGCAAGC CGATCCTGCT GCAGCGGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu50028 | |
Clone ID Related Accession (Same CDS sequence) | XM_006519064.1 , XM_006519064.2 | |
Accession Version | XM_006519064.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | WD repeat and FYVE domain-containing protein 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAATGCC TTGAGTTTAT TTTGTCTGAA GATTATAACA AGATGACACC TGTGAAAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006519127.1 |
CDS | 230..1165 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCAATGCC TTGAGTTTAT TTTGTCTGAA GATTATAACA AGATGACACC TGTGAAAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu50029 | |
Clone ID Related Accession (Same CDS sequence) | XM_006519065.3 , XM_006519065.4 | |
Accession Version | XM_006519065.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 801bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | WD repeat and FYVE domain-containing protein 2 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006519065.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGCGG AGATCCAGCC CCAGCCACTG ACCCGCAAGC CGATCCTGCT GCAGCGGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006519128.1 |
CDS | 104..904 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCGGCGG AGATCCAGCC CCAGCCACTG ACCCGCAAGC CGATCCTGCT GCAGCGGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu05551 | |
Clone ID Related Accession (Same CDS sequence) | NM_175546.4 | |
Accession Version | NM_175546.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1203bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-22 | |
Organism | Mus musculus(house mouse) | |
Product | WD repeat and FYVE domain-containing protein 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK086275.1, AK151817.1 and CB520148.1. On Jul 21, 2009 this sequence version replaced NM_175546.3. ##Evidence-Data-START## Transcript exon combination :: AK131958.1, AK151817.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGGCGG AGATCCAGCC CCAGCCACTG ACCCGCAAGC CGATCCTGCT GCAGCGGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_780755.2 |
CDS | 232..1434 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCGGCGG AGATCCAGCC CCAGCCACTG ACCCGCAAGC CGATCCTGCT GCAGCGGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu50028 | |
Clone ID Related Accession (Same CDS sequence) | XM_006519064.1 , XM_006519064.2 | |
Accession Version | XM_006519064.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | WD repeat and FYVE domain-containing protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006519064.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAATGCC TTGAGTTTAT TTTGTCTGAA GATTATAACA AGATGACACC TGTGAAAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006519127.1 |
CDS | 454..1389 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCAATGCC TTGAGTTTAT TTTGTCTGAA GATTATAACA AGATGACACC TGTGAAAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu50029 | |
Clone ID Related Accession (Same CDS sequence) | XM_006519065.3 , XM_006519065.4 | |
Accession Version | XM_006519065.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 801bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | WD repeat and FYVE domain-containing protein 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006519065.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGCGG AGATCCAGCC CCAGCCACTG ACCCGCAAGC CGATCCTGCT GCAGCGGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006519128.1 |
CDS | 184..984 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCGGCGG AGATCCAGCC CCAGCCACTG ACCCGCAAGC CGATCCTGCT GCAGCGGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Akt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis. |
WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta. |
A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda. |