Gene Symbol | Ss18 |
Entrez Gene ID | 268996 |
Full Name | SS18, nBAF chromatin remodeling complex subunit |
Synonyms | D130059H17,Ssxt,Syt |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Ss18 cDNA ORF clone
gRNAs
Gene Symbol | Ss18 |
Entrez Gene ID | 268996 |
Full Name | SS18, nBAF chromatin remodeling complex subunit |
Synonyms | D130059H17,Ssxt,Syt |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001161371.1 | NP_001154843.1 | protein SSXT isoform 4 |
NM_001161370.1 | NP_001154842.1 | protein SSXT isoform 3 |
NM_009280.2 | NP_033306.2 | protein SSXT isoform 1 |
XM_006525948.2 | XP_006526011.1 | protein SSXT isoform X1 |
XM_006525948.3 | XP_006526011.1 | protein SSXT isoform X1 |
XM_030250469.1 | XP_030106329.1 | protein SSXT isoform X2 |
NM_001161369.1 | NP_001154841.1 | protein SSXT isoform 2 |
Homo sapiens (human) | SS18 | NP_001007560.1 |
Mus musculus (house mouse) | Ss18 | NP_033306.2 |
Gallus gallus (chicken) | SS18 | NP_001265079.1 |
Danio rerio (zebrafish) | ss18 | NP_956038.1 |
Canis lupus familiaris (dog) | SS18 | XP_537295.3 |
Rattus norvegicus (Norway rat) | Ss18 | NP_001094370.1 |
Xenopus tropicalis (tropical clawed frog) | ss18 | NP_001072937.1 |
Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.
Staahl BT, Tang J, Wu W, Sun A, Gitler AD, Yoo AS, Crabtree GR
The Journal of neuroscience : the official journal of the Society for Neuroscience33(25)10348-61(2013 Jun)
Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma.
Kadoch C, Crabtree GR
Cell153(1)71-85(2013 Mar)
Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics.
Su L, Sampaio AV, Jones KB, Pacheco M, Goytain A, Lin S, Poulin N, Yi L, Rossi FM, Kast J, Capecchi MR, Underhill TM, Nielsen TO
Cancer cell21(3)333-47(2012 Mar)
The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.
Krentz AD, Murphy MW, Kim S, Cook MS, Capel B, Zhu R, Matin A, Sarver AL, Parker KL, Griswold MD, Looijenga LH, Bardwell VJ, Zarkower D
Proceedings of the National Academy of Sciences of the United States of America106(52)22323-8(2009 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Syt may contribute to the signaling pathway important for various cellular functions in vivo and in vitro, and we propose that Syt-deficient MEFs would be a powerful means to understand the biological roles of SYT in vitro.
Title: Human synovial sarcoma proto-oncogene Syt is essential for early embryonic development through the regulation of cell migration.
disruption of the Ss18 gene results in a recessive embryonic lethal phenotype, due to placental failure caused by impairment of placental vascularization and/or chorio-allantoic fusion
Title: Targeted disruption of the synovial sarcoma-associated SS18 gene causes early embryonic lethality and affects PPARBP expression.
The following Ss18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ss18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu03859 | |
Clone ID Related Accession (Same CDS sequence) | NM_009280.2 | |
Accession Version | NM_009280.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-22 | |
Organism | Mus musculus(house mouse) | |
Product | protein SSXT isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY021731.1, CF104258.1, AK166053.1 and BC065062.1. On May 29, 2009 this sequence version replaced NM_009280.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X93357.1, AK083887.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02146467 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_033306.2 |
CDS | 180..1436 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu08130 | |
Clone ID Related Accession (Same CDS sequence) | NM_001161369.1 | |
Accession Version | NM_001161369.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1164bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-23 | |
Organism | Mus musculus(house mouse) | |
Product | protein SSXT isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY021731.1, CF104258.1 and BC065062.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065062.1, AK083622.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02146467 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001154841.1 |
CDS | 180..1343 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu08131 | |
Clone ID Related Accession (Same CDS sequence) | NM_001161370.1 | |
Accession Version | NM_001161370.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-23 | |
Organism | Mus musculus(house mouse) | |
Product | protein SSXT isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY021731.1, CF104258.1, AK051601.1 and BC065062.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK051601.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02146467 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001154842.1 |
CDS | 180..1214 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu08133 | |
Clone ID Related Accession (Same CDS sequence) | NM_001161371.1 | |
Accession Version | NM_001161371.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 942bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-24 | |
Organism | Mus musculus(house mouse) | |
Product | protein SSXT isoform 4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY021731.1, CF104258.1, AK052476.1 and BC065062.1. Transcript Variant: This variant (4) lacks two alternate in-frame exons compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.69694.1, AK052476.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02146467 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001154843.1 |
CDS | 180..1121 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu54596 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525948.2 , XM_006525948.3 | |
Accession Version | XM_006525948.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1059bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | protein SSXT isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006525948.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006526011.1 |
CDS | 268..1326 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu54596 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525948.2 , XM_006525948.3 | |
Accession Version | XM_006525948.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1059bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | protein SSXT isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006525948.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006526011.1 |
CDS | 1685..2743 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu87400 | |
Clone ID Related Accession (Same CDS sequence) | XM_030250469.1 | |
Accession Version | XM_030250469.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 837bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | protein SSXT isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030106329.1 |
CDS | 1685..2521 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTCTGTGG CGTTCGCAGC CCCGAGGCAG CGGGGCAAGG GCGAAATCAC GCCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways. |
Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma. |
Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics. |
The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency. |